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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC25A12
Full Name:
Calcium-binding mitochondrial carrier protein Aralar1
Alias:
ARALAR; ARALAR1; calcium-binding mitochondrial carrier Aralar1; CMC1; mitochondrial aspartate glutamate carrier 1; solute carrier family 25 (mitochondrial carrier, Aralar) member 12; solute carrier family 25 member 12
Type:
Transporter
Mass (Da):
74762
Number AA:
678
UniProt ID:
O75746
International Prot ID:
IPI00386271
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005743
Uniprot
OncoNet
Molecular Function:
GO:0015183
GO:0005313
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0015813
GO:0015810
GO:0043490
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
V
K
V
Q
T
T
K
R
G
D
P
H
E
Site 2
T26
I
F
L
Q
Y
A
S
T
E
V
D
G
E
R
Y
Site 3
Y33
T
E
V
D
G
E
R
Y
M
T
P
E
D
F
V
Site 4
T35
V
D
G
E
R
Y
M
T
P
E
D
F
V
Q
R
Site 5
Y43
P
E
D
F
V
Q
R
Y
L
G
L
Y
N
D
P
Site 6
Y47
V
Q
R
Y
L
G
L
Y
N
D
P
N
S
N
P
Site 7
S52
G
L
Y
N
D
P
N
S
N
P
K
I
V
Q
L
Site 8
S73
Q
T
K
D
G
L
I
S
Y
Q
E
F
L
A
F
Site 9
Y74
T
K
D
G
L
I
S
Y
Q
E
F
L
A
F
E
Site 10
S101
A
F
Q
L
F
D
K
S
G
N
G
E
V
T
F
Site 11
T107
K
S
G
N
G
E
V
T
F
E
N
V
K
E
I
Site 12
S172
A
F
A
L
K
D
K
S
K
S
G
M
I
S
G
Site 13
S174
A
L
K
D
K
S
K
S
G
M
I
S
G
L
D
Site 14
S178
K
S
K
S
G
M
I
S
G
L
D
F
S
D
I
Site 15
T195
T
I
R
S
H
M
L
T
P
F
V
E
E
N
L
Site 16
S211
S
A
A
G
G
S
I
S
H
Q
V
S
F
S
Y
Site 17
Y218
S
H
Q
V
S
F
S
Y
F
N
A
F
N
S
L
Site 18
S224
S
Y
F
N
A
F
N
S
L
L
N
N
M
E
L
Site 19
Y236
M
E
L
V
R
K
I
Y
S
T
L
A
G
T
R
Site 20
S237
E
L
V
R
K
I
Y
S
T
L
A
G
T
R
K
Site 21
T238
L
V
R
K
I
Y
S
T
L
A
G
T
R
K
D
Site 22
T249
T
R
K
D
V
E
V
T
K
E
E
F
A
Q
S
Site 23
S256
T
K
E
E
F
A
Q
S
A
I
R
Y
G
Q
V
Site 24
Y260
F
A
Q
S
A
I
R
Y
G
Q
V
T
P
L
E
Site 25
Y278
L
Y
Q
L
A
D
L
Y
N
A
S
G
R
L
T
Site 26
T285
Y
N
A
S
G
R
L
T
L
A
D
I
E
R
I
Site 27
S312
A
E
L
Q
R
Q
Q
S
P
G
L
G
R
P
I
Site 28
S360
R
M
Q
N
Q
R
G
S
G
S
V
V
G
E
L
Site 29
S362
Q
N
Q
R
G
S
G
S
V
V
G
E
L
M
Y
Site 30
Y369
S
V
V
G
E
L
M
Y
K
N
S
F
D
C
F
Site 31
T408
P
E
K
A
I
K
L
T
V
N
D
F
V
R
D
Site 32
T418
D
F
V
R
D
K
F
T
R
R
D
G
S
V
P
Site 33
S423
K
F
T
R
R
D
G
S
V
P
L
P
A
E
V
Site 34
T556
A
A
R
A
G
Q
T
T
Y
S
G
V
I
D
C
Site 35
S558
R
A
G
Q
T
T
Y
S
G
V
I
D
C
F
R
Site 36
S574
I
L
R
E
E
G
P
S
A
F
W
K
G
T
A
Site 37
Y606
E
L
L
Q
R
W
F
Y
I
D
F
G
G
L
K
Site 38
S617
G
G
L
K
P
A
G
S
E
P
T
P
K
S
R
Site 39
T620
K
P
A
G
S
E
P
T
P
K
S
R
I
A
D
Site 40
S623
G
S
E
P
T
P
K
S
R
I
A
D
L
P
P
Site 41
T645
G
Y
R
L
A
T
A
T
F
A
G
I
E
N
K
Site 42
Y656
I
E
N
K
F
G
L
Y
L
P
K
F
K
S
P
Site 43
S664
L
P
K
F
K
S
P
S
V
A
V
V
Q
P
K
Site 44
T677
P
K
A
A
V
A
A
T
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation