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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HUG1
Full Name:
Protein HUG-1
Alias:
HOX11 upstream gene 1 protein
Type:
Mass (Da):
39387
Number AA:
362
UniProt ID:
O75698
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y39
A
D
A
R
Q
R
L
Y
V
G
P
R
A
V
P
Site 2
S67
P
L
G
M
G
A
W
S
P
Y
K
S
H
P
C
Site 3
T76
Y
K
S
H
P
C
V
T
T
N
S
S
N
N
S
Site 4
T77
K
S
H
P
C
V
T
T
N
S
S
N
N
S
C
Site 5
S79
H
P
C
V
T
T
N
S
S
N
N
S
C
P
A
Site 6
S80
P
C
V
T
T
N
S
S
N
N
S
C
P
A
V
Site 7
S83
T
T
N
S
S
N
N
S
C
P
A
V
P
V
H
Site 8
T95
P
V
H
F
T
I
S
T
P
P
S
I
P
P
H
Site 9
S98
F
T
I
S
T
P
P
S
I
P
P
H
W
Q
G
Site 10
T120
H
S
R
A
H
G
R
T
P
R
P
T
R
S
S
Site 11
T124
H
G
R
T
P
R
P
T
R
S
S
Q
T
H
T
Site 12
S127
T
P
R
P
T
R
S
S
Q
T
H
T
T
L
R
Site 13
T131
T
R
S
S
Q
T
H
T
T
L
R
K
A
P
N
Site 14
T132
R
S
S
Q
T
H
T
T
L
R
K
A
P
N
W
Site 15
S140
L
R
K
A
P
N
W
S
N
S
Q
Q
W
P
S
Site 16
S147
S
N
S
Q
Q
W
P
S
P
H
P
P
L
A
P
Site 17
S157
P
P
L
A
P
P
R
S
S
F
P
T
F
V
G
Site 18
S158
P
L
A
P
P
R
S
S
F
P
T
F
V
G
K
Site 19
T161
P
P
R
S
S
F
P
T
F
V
G
K
G
H
R
Site 20
T176
N
A
G
Q
L
R
R
T
G
Q
R
R
A
T
G
Site 21
T182
R
T
G
Q
R
R
A
T
G
P
P
G
V
S
F
Site 22
S201
P
L
I
T
V
P
Q
S
S
W
G
S
R
A
P
Site 23
S205
V
P
Q
S
S
W
G
S
R
A
P
R
A
A
R
Site 24
S213
R
A
P
R
A
A
R
S
P
R
D
N
G
I
I
Site 25
S221
P
R
D
N
G
I
I
S
G
E
R
G
R
L
G
Site 26
S239
R
R
R
R
L
L
P
S
I
R
P
S
A
P
K
Site 27
S243
L
L
P
S
I
R
P
S
A
P
K
E
R
L
R
Site 28
T254
E
R
L
R
R
P
E
T
S
G
I
S
D
A
G
Site 29
S255
R
L
R
R
P
E
T
S
G
I
S
D
A
G
G
Site 30
S273
A
G
P
G
R
P
N
S
I
S
W
A
A
A
A
Site 31
S275
P
G
R
P
N
S
I
S
W
A
A
A
A
S
V
Site 32
S290
R
L
W
A
R
R
D
S
S
S
G
Q
L
L
F
Site 33
S291
L
W
A
R
R
D
S
S
S
G
Q
L
L
F
V
Site 34
S292
W
A
R
R
D
S
S
S
G
Q
L
L
F
V
H
Site 35
Y304
F
V
H
E
D
H
A
Y
G
C
G
S
S
P
F
Site 36
S308
D
H
A
Y
G
C
G
S
S
P
F
G
A
H
P
Site 37
S309
H
A
Y
G
C
G
S
S
P
F
G
A
H
P
T
Site 38
S329
H
L
R
V
A
P
P
S
H
S
F
P
A
R
E
Site 39
S331
R
V
A
P
P
S
H
S
F
P
A
R
E
G
D
Site 40
S354
K
L
W
L
L
L
S
S
L
W
P
S
S
E
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation