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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CENTA1
Full Name:
Arf-GAP with dual PH domain-containing protein 1
Alias:
CENA1; Centaurin-alpha 1; MAPK-activating protein PM25
Type:
Uncharacterized protein
Mass (Da):
43395
Number AA:
374
UniProt ID:
O75689
International Prot ID:
IPI00009992
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0008060
GO:0043533
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007166
GO:0032312
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S55
H
R
N
I
P
Q
V
S
K
V
K
S
V
R
L
Site 2
S59
P
Q
V
S
K
V
K
S
V
R
L
D
A
W
E
Site 3
S87
A
A
R
A
R
F
E
S
K
V
P
S
F
Y
Y
Site 4
S91
R
F
E
S
K
V
P
S
F
Y
Y
R
P
T
P
Site 5
Y93
E
S
K
V
P
S
F
Y
Y
R
P
T
P
S
D
Site 6
Y94
S
K
V
P
S
F
Y
Y
R
P
T
P
S
D
C
Site 7
T97
P
S
F
Y
Y
R
P
T
P
S
D
C
Q
L
L
Site 8
S99
F
Y
Y
R
P
T
P
S
D
C
Q
L
L
R
E
Site 9
Y113
E
Q
W
I
R
A
K
Y
E
R
Q
E
F
I
Y
Site 10
Y120
Y
E
R
Q
E
F
I
Y
P
E
K
Q
E
P
Y
Site 11
S128
P
E
K
Q
E
P
Y
S
A
G
Y
R
E
G
F
Site 12
Y131
Q
E
P
Y
S
A
G
Y
R
E
G
F
L
W
K
Site 13
S148
R
D
N
G
Q
F
L
S
R
K
F
V
L
T
E
Site 14
T154
L
S
R
K
F
V
L
T
E
R
E
G
A
L
K
Site 15
Y162
E
R
E
G
A
L
K
Y
F
N
R
N
D
A
K
Site 16
T183
K
I
E
H
L
N
A
T
F
Q
P
A
K
I
G
Site 17
Y199
P
H
G
L
Q
V
T
Y
L
K
D
N
S
T
R
Site 18
Y211
S
T
R
N
I
F
I
Y
H
E
D
G
K
E
I
Site 19
Y232
L
R
A
A
R
F
H
Y
L
Q
V
A
F
P
G
Site 20
S250
A
D
L
V
P
K
L
S
R
N
Y
L
K
E
G
Site 21
Y253
V
P
K
L
S
R
N
Y
L
K
E
G
Y
M
E
Site 22
Y258
R
N
Y
L
K
E
G
Y
M
E
K
T
G
P
K
Site 23
T262
K
E
G
Y
M
E
K
T
G
P
K
Q
T
E
G
Site 24
T276
G
F
R
K
R
W
F
T
M
D
D
R
R
L
M
Site 25
Y284
M
D
D
R
R
L
M
Y
F
K
D
P
L
D
A
Site 26
S301
R
G
E
V
F
I
G
S
K
E
S
G
Y
T
V
Site 27
Y306
I
G
S
K
E
S
G
Y
T
V
L
H
G
F
P
Site 28
T307
G
S
K
E
S
G
Y
T
V
L
H
G
F
P
P
Site 29
T340
K
F
L
F
A
C
E
T
E
S
D
Q
R
E
W
Site 30
S342
L
F
A
C
E
T
E
S
D
Q
R
E
W
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation