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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WBP4
Full Name:
WW domain-binding protein 4
Alias:
Domain-containing binding protein 4; FBP21; FNBP21; Formin binding protein 21; Formin-binding 21; Formin-binding protein 21; MGC117310; WBP-4; WW; WW domain binding 4; WW domain binding protein 4; WW domain-containing-binding protein 4
Type:
RNA processing
Mass (Da):
42507
Number AA:
376
UniProt ID:
O75554
International Prot ID:
IPI00026957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0070064
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045292
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
D
Y
W
K
S
Q
P
K
K
F
C
D
Site 2
Y15
Q
P
K
K
F
C
D
Y
C
K
C
W
I
A
D
Site 3
S26
W
I
A
D
N
R
P
S
V
E
F
H
E
R
G
Site 4
S45
E
N
V
A
K
R
I
S
E
I
K
Q
K
S
L
Site 5
S51
I
S
E
I
K
Q
K
S
L
D
K
A
K
E
E
Site 6
S87
L
K
R
L
G
L
E
S
E
I
L
E
P
S
I
Site 7
S93
E
S
E
I
L
E
P
S
I
T
P
V
T
S
T
Site 8
T98
E
P
S
I
T
P
V
T
S
T
I
P
P
T
S
Site 9
S99
P
S
I
T
P
V
T
S
T
I
P
P
T
S
T
Site 10
T100
S
I
T
P
V
T
S
T
I
P
P
T
S
T
S
Site 11
T104
V
T
S
T
I
P
P
T
S
T
S
N
Q
Q
K
Site 12
S105
T
S
T
I
P
P
T
S
T
S
N
Q
Q
K
E
Site 13
T106
S
T
I
P
P
T
S
T
S
N
Q
Q
K
E
K
Site 14
S124
K
K
R
K
K
D
P
S
K
G
R
W
V
E
G
Site 15
Y137
E
G
I
T
S
E
G
Y
H
Y
Y
Y
D
L
I
Site 16
Y139
I
T
S
E
G
Y
H
Y
Y
Y
D
L
I
S
G
Site 17
Y140
T
S
E
G
Y
H
Y
Y
Y
D
L
I
S
G
A
Site 18
Y141
S
E
G
Y
H
Y
Y
Y
D
L
I
S
G
A
S
Site 19
S148
Y
D
L
I
S
G
A
S
Q
W
E
K
P
E
G
Site 20
T179
G
L
S
E
D
G
F
T
Y
Y
Y
N
T
E
T
Site 21
Y180
L
S
E
D
G
F
T
Y
Y
Y
N
T
E
T
G
Site 22
Y181
S
E
D
G
F
T
Y
Y
Y
N
T
E
T
G
E
Site 23
Y182
E
D
G
F
T
Y
Y
Y
N
T
E
T
G
E
S
Site 24
T184
G
F
T
Y
Y
Y
N
T
E
T
G
E
S
R
W
Site 25
S189
Y
N
T
E
T
G
E
S
R
W
E
K
P
D
D
Site 26
T201
P
D
D
F
I
P
H
T
S
D
L
P
S
S
K
Site 27
S202
D
D
F
I
P
H
T
S
D
L
P
S
S
K
V
Site 28
S206
P
H
T
S
D
L
P
S
S
K
V
N
E
N
S
Site 29
S207
H
T
S
D
L
P
S
S
K
V
N
E
N
S
L
Site 30
S213
S
S
K
V
N
E
N
S
L
G
T
L
D
E
S
Site 31
T216
V
N
E
N
S
L
G
T
L
D
E
S
K
S
S
Site 32
S220
S
L
G
T
L
D
E
S
K
S
S
D
S
H
S
Site 33
S222
G
T
L
D
E
S
K
S
S
D
S
H
S
D
S
Site 34
S223
T
L
D
E
S
K
S
S
D
S
H
S
D
S
D
Site 35
S225
D
E
S
K
S
S
D
S
H
S
D
S
D
G
E
Site 36
S227
S
K
S
S
D
S
H
S
D
S
D
G
E
Q
E
Site 37
S229
S
S
D
S
H
S
D
S
D
G
E
Q
E
A
E
Site 38
S241
E
A
E
E
G
G
V
S
T
E
T
E
K
P
K
Site 39
T244
E
G
G
V
S
T
E
T
E
K
P
K
I
K
F
Site 40
S258
F
K
E
K
N
K
N
S
D
G
G
S
D
P
E
Site 41
S262
N
K
N
S
D
G
G
S
D
P
E
T
Q
K
E
Site 42
T266
D
G
G
S
D
P
E
T
Q
K
E
K
S
I
Q
Site 43
S271
P
E
T
Q
K
E
K
S
I
Q
K
Q
N
S
L
Site 44
S277
K
S
I
Q
K
Q
N
S
L
G
S
N
E
E
K
Site 45
S280
Q
K
Q
N
S
L
G
S
N
E
E
K
S
K
T
Site 46
S285
L
G
S
N
E
E
K
S
K
T
L
K
K
S
N
Site 47
T287
S
N
E
E
K
S
K
T
L
K
K
S
N
P
Y
Site 48
S291
K
S
K
T
L
K
K
S
N
P
Y
G
E
W
Q
Site 49
S316
E
V
D
L
E
L
P
S
T
E
N
E
Y
V
S
Site 50
T317
V
D
L
E
L
P
S
T
E
N
E
Y
V
S
T
Site 51
Y321
L
P
S
T
E
N
E
Y
V
S
T
S
E
A
D
Site 52
S323
S
T
E
N
E
Y
V
S
T
S
E
A
D
G
G
Site 53
T324
T
E
N
E
Y
V
S
T
S
E
A
D
G
G
G
Site 54
S325
E
N
E
Y
V
S
T
S
E
A
D
G
G
G
E
Site 55
T361
P
V
F
K
K
R
R
T
E
N
G
K
S
R
N
Site 56
S366
R
R
T
E
N
G
K
S
R
N
L
R
Q
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation