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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EED
Full Name:
Polycomb protein EED
Alias:
HEED; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1
Type:
Unknown function
Mass (Da):
57907
Number AA:
517
UniProt ID:
O75530
International Prot ID:
IPI00171248
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0035098
Uniprot
OncoNet
Molecular Function:
GO:0042054
GO:0042802
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0016481
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
S
E
R
E
V
S
T
A
P
A
G
T
D
Site 2
S25
A
K
K
Q
K
L
S
S
D
E
N
S
N
P
D
Site 3
S29
K
L
S
S
D
E
N
S
N
P
D
L
S
G
D
Site 4
S34
E
N
S
N
P
D
L
S
G
D
E
N
D
D
A
Site 5
S43
D
E
N
D
D
A
V
S
I
E
S
G
T
N
T
Site 6
T50
S
I
E
S
G
T
N
T
E
R
P
D
T
P
T
Site 7
T55
T
N
T
E
R
P
D
T
P
T
N
T
P
N
A
Site 8
T57
T
E
R
P
D
T
P
T
N
T
P
N
A
P
G
Site 9
T59
R
P
D
T
P
T
N
T
P
N
A
P
G
R
K
Site 10
S67
P
N
A
P
G
R
K
S
W
G
K
G
K
W
K
Site 11
S81
K
S
K
K
C
K
Y
S
F
K
C
V
N
S
L
Site 12
S105
G
V
Q
F
N
W
H
S
K
E
G
D
P
L
V
Site 13
T122
T
V
G
S
N
R
V
T
L
Y
E
C
H
S
Q
Site 14
Y124
G
S
N
R
V
T
L
Y
E
C
H
S
Q
G
E
Site 15
S128
V
T
L
Y
E
C
H
S
Q
G
E
I
R
L
L
Site 16
Y138
E
I
R
L
L
Q
S
Y
V
D
A
D
A
D
E
Site 17
Y148
A
D
A
D
E
N
F
Y
T
C
A
W
T
Y
D
Site 18
T158
A
W
T
Y
D
S
N
T
S
H
P
L
L
A
V
Site 19
S208
R
D
P
N
L
L
L
S
V
S
K
D
H
A
L
Site 20
S241
G
H
R
D
E
V
L
S
A
D
Y
D
L
L
G
Site 21
Y244
D
E
V
L
S
A
D
Y
D
L
L
G
E
K
I
Site 22
Y280
A
I
K
E
S
Y
D
Y
N
P
N
K
T
N
R
Site 23
S291
K
T
N
R
P
F
I
S
Q
K
I
H
F
P
D
Site 24
Y308
T
R
D
I
H
R
N
Y
V
D
C
V
R
W
L
Site 25
T351
K
P
S
E
S
N
V
T
I
L
G
R
F
D
Y
Site 26
Y358
T
I
L
G
R
F
D
Y
S
Q
C
D
I
W
Y
Site 27
Y387
G
N
Q
V
G
K
L
Y
V
W
D
L
E
V
E
Site 28
T405
K
A
K
C
T
T
L
T
H
H
K
C
G
A
A
Site 29
T416
C
G
A
A
I
R
Q
T
S
F
S
R
D
S
S
Site 30
S417
G
A
A
I
R
Q
T
S
F
S
R
D
S
S
I
Site 31
S419
A
I
R
Q
T
S
F
S
R
D
S
S
I
L
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation