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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SUPT3H
Full Name:
Transcription initiation protein SPT3 homolog
Alias:
SPT3; SPT3L; SPT3-like protein; Suppressor of Ty 3; SUPT3; Transcription initiation protein SPT3
Type:
Mass (Da):
35793
Number AA:
317
UniProt ID:
O75486
International Prot ID:
IPI00303875
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030914
GO:0033276
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003702
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0043966
GO:0016578
GO:0006357
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
Y
S
P
R
G
S
Q
G
R
G
T
A
E
Site 2
T12
R
G
S
Q
G
R
G
T
A
E
A
T
A
N
S
Site 3
S19
T
A
E
A
T
A
N
S
P
S
P
P
I
A
P
Site 4
S21
E
A
T
A
N
S
P
S
P
P
I
A
P
S
H
Site 5
S27
P
S
P
P
I
A
P
S
H
S
R
V
T
F
S
Site 6
S29
P
P
I
A
P
S
H
S
R
V
T
F
S
L
S
Site 7
T32
A
P
S
H
S
R
V
T
F
S
L
S
T
L
H
Site 8
S34
S
H
S
R
V
T
F
S
L
S
T
L
H
T
L
Site 9
T40
F
S
L
S
T
L
H
T
L
S
P
P
P
R
P
Site 10
S42
L
S
T
L
H
T
L
S
P
P
P
R
P
F
P
Site 11
S50
P
P
P
R
P
F
P
S
V
S
R
A
A
A
Q
Site 12
S52
P
R
P
F
P
S
V
S
R
A
A
A
Q
K
P
Site 13
T86
L
K
A
E
M
N
N
T
A
A
S
P
M
S
T
Site 14
S89
E
M
N
N
T
A
A
S
P
M
S
T
A
T
S
Site 15
S92
N
T
A
A
S
P
M
S
T
A
T
S
S
S
G
Site 16
T93
T
A
A
S
P
M
S
T
A
T
S
S
S
G
R
Site 17
T95
A
S
P
M
S
T
A
T
S
S
S
G
R
S
T
Site 18
S96
S
P
M
S
T
A
T
S
S
S
G
R
S
T
G
Site 19
S97
P
M
S
T
A
T
S
S
S
G
R
S
T
G
K
Site 20
S98
M
S
T
A
T
S
S
S
G
R
S
T
G
K
S
Site 21
S101
A
T
S
S
S
G
R
S
T
G
K
S
I
S
F
Site 22
T102
T
S
S
S
G
R
S
T
G
K
S
I
S
F
A
Site 23
S105
S
G
R
S
T
G
K
S
I
S
F
A
T
E
L
Site 24
S107
R
S
T
G
K
S
I
S
F
A
T
E
L
Q
S
Site 25
T110
G
K
S
I
S
F
A
T
E
L
Q
S
M
M
Y
Site 26
S114
S
F
A
T
E
L
Q
S
M
M
Y
S
L
G
D
Site 27
S118
E
L
Q
S
M
M
Y
S
L
G
D
A
R
R
P
Site 28
T129
A
R
R
P
L
H
E
T
A
V
L
V
E
D
V
Site 29
S152
L
Q
Q
A
A
E
V
S
Q
L
R
G
A
R
V
Site 30
Y182
K
L
R
R
L
L
K
Y
M
F
I
R
D
Y
K
Site 31
Y188
K
Y
M
F
I
R
D
Y
K
S
K
I
V
K
G
Site 32
S207
D
L
L
E
D
K
L
S
G
S
N
N
A
N
K
Site 33
T256
M
E
R
A
E
R
Q
T
R
I
M
D
S
A
Q
Site 34
S261
R
Q
T
R
I
M
D
S
A
Q
Y
A
E
F
C
Site 35
Y264
R
I
M
D
S
A
Q
Y
A
E
F
C
E
S
R
Site 36
S270
Q
Y
A
E
F
C
E
S
R
Q
L
S
F
S
K
Site 37
S274
F
C
E
S
R
Q
L
S
F
S
K
K
A
S
K
Site 38
S276
E
S
R
Q
L
S
F
S
K
K
A
S
K
F
R
Site 39
S280
L
S
F
S
K
K
A
S
K
F
R
D
W
L
D
Site 40
T327
L
V
R
Q
D
M
V
T
K
A
G
D
P
F
S
Site 41
S334
T
K
A
G
D
P
F
S
H
A
I
S
A
T
F
Site 42
T340
F
S
H
A
I
S
A
T
F
I
Q
Y
H
N
S
Site 43
S350
Q
Y
H
N
S
A
E
S
T
A
A
C
G
V
E
Site 44
Y375
I
R
E
A
I
R
R
Y
S
H
R
I
G
P
L
Site 45
S376
R
E
A
I
R
R
Y
S
H
R
I
G
P
L
S
Site 46
S383
S
H
R
I
G
P
L
S
P
F
T
N
A
Y
R
Site 47
T386
I
G
P
L
S
P
F
T
N
A
Y
R
R
N
G
Site 48
Y389
L
S
P
F
T
N
A
Y
R
R
N
G
M
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation