KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PSIP1
Full Name:
PC4 and SFRS1-interacting protein
Alias:
CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS70; LEDGF; Lens epithelium-derived growth factor; P52; P75; PAIP; PSIP2; Transcriptional coactivator p52/p75
Type:
Nucleus protein; Transcription protein, coactivator/corepressor
Mass (Da):
60103
Number AA:
530
UniProt ID:
O75475
International Prot ID:
IPI00028122
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003677
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0019059
GO:0044419
GO:0019047
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
D
G
A
V
K
P
P
T
N
K
L
P
I
F
F
Site 2
S62
P
K
D
I
F
P
Y
S
E
N
K
E
K
Y
G
Site 3
Y68
Y
S
E
N
K
E
K
Y
G
K
P
N
K
R
K
Site 4
S94
N
P
K
V
K
F
S
S
Q
Q
A
A
T
K
Q
Site 5
T99
F
S
S
Q
Q
A
A
T
K
Q
S
N
A
S
S
Site 6
S102
Q
Q
A
A
T
K
Q
S
N
A
S
S
D
V
E
Site 7
S105
A
T
K
Q
S
N
A
S
S
D
V
E
V
E
E
Site 8
S106
T
K
Q
S
N
A
S
S
D
V
E
V
E
E
K
Site 9
T115
V
E
V
E
E
K
E
T
S
V
S
K
E
D
T
Site 10
S116
E
V
E
E
K
E
T
S
V
S
K
E
D
T
D
Site 11
S118
E
E
K
E
T
S
V
S
K
E
D
T
D
H
E
Site 12
T122
T
S
V
S
K
E
D
T
D
H
E
E
K
A
S
Site 13
S129
T
D
H
E
E
K
A
S
N
E
D
V
T
K
A
Site 14
T134
K
A
S
N
E
D
V
T
K
A
V
D
I
T
T
Site 15
T140
V
T
K
A
V
D
I
T
T
P
K
A
A
R
R
Site 16
T141
T
K
A
V
D
I
T
T
P
K
A
A
R
R
G
Site 17
T166
T
E
E
A
G
V
V
T
T
A
T
A
S
V
N
Site 18
T167
E
E
A
G
V
V
T
T
A
T
A
S
V
N
L
Site 19
T169
A
G
V
V
T
T
A
T
A
S
V
N
L
K
V
Site 20
S171
V
V
T
T
A
T
A
S
V
N
L
K
V
S
P
Site 21
S177
A
S
V
N
L
K
V
S
P
K
R
G
R
P
A
Site 22
T186
K
R
G
R
P
A
A
T
E
V
K
I
P
K
P
Site 23
S206
M
V
K
Q
P
C
P
S
E
S
D
I
I
T
E
Site 24
S208
K
Q
P
C
P
S
E
S
D
I
I
T
E
E
D
Site 25
T212
P
S
E
S
D
I
I
T
E
E
D
K
S
K
K
Site 26
S217
I
I
T
E
E
D
K
S
K
K
K
G
Q
E
E
Site 27
S259
E
G
K
K
E
V
E
S
K
R
K
N
L
A
K
Site 28
T267
K
R
K
N
L
A
K
T
G
V
T
S
T
S
D
Site 29
T270
N
L
A
K
T
G
V
T
S
T
S
D
S
E
E
Site 30
S271
L
A
K
T
G
V
T
S
T
S
D
S
E
E
E
Site 31
T272
A
K
T
G
V
T
S
T
S
D
S
E
E
E
G
Site 32
S273
K
T
G
V
T
S
T
S
D
S
E
E
E
G
D
Site 33
S275
G
V
T
S
T
S
D
S
E
E
E
G
D
D
Q
Site 34
T296
K
G
G
R
N
F
Q
T
A
H
R
R
N
M
L
Site 35
T346
K
V
E
K
K
R
E
T
S
M
D
S
R
L
Q
Site 36
S347
V
E
K
K
R
E
T
S
M
D
S
R
L
Q
R
Site 37
S382
E
A
L
D
E
L
A
S
L
Q
V
T
M
Q
Q
Site 38
T399
K
H
T
E
M
I
T
T
L
K
K
I
R
R
F
Site 39
S409
K
I
R
R
F
K
V
S
Q
V
I
M
E
K
S
Site 40
Y420
M
E
K
S
T
M
L
Y
N
K
F
K
N
M
F
Site 41
S434
F
L
V
G
E
G
D
S
V
I
T
Q
V
L
N
Site 42
T437
G
E
G
D
S
V
I
T
Q
V
L
N
K
S
L
Site 43
S443
I
T
Q
V
L
N
K
S
L
A
E
Q
R
Q
H
Site 44
T456
Q
H
E
E
A
N
K
T
K
D
Q
G
K
K
G
Site 45
T473
K
K
L
E
K
E
Q
T
G
S
K
T
L
N
G
Site 46
S475
L
E
K
E
Q
T
G
S
K
T
L
N
G
G
S
Site 47
T477
K
E
Q
T
G
S
K
T
L
N
G
G
S
D
A
Site 48
S482
S
K
T
L
N
G
G
S
D
A
Q
D
G
N
Q
Site 49
S496
Q
P
Q
H
N
G
E
S
N
E
D
S
K
D
N
Site 50
S500
N
G
E
S
N
E
D
S
K
D
N
H
E
A
S
Site 51
S507
S
K
D
N
H
E
A
S
T
K
K
K
P
S
S
Site 52
T508
K
D
N
H
E
A
S
T
K
K
K
P
S
S
E
Site 53
S513
A
S
T
K
K
K
P
S
S
E
E
R
E
T
E
Site 54
S514
S
T
K
K
K
P
S
S
E
E
R
E
T
E
I
Site 55
T519
P
S
S
E
E
R
E
T
E
I
S
L
K
D
S
Site 56
S522
E
E
R
E
T
E
I
S
L
K
D
S
T
L
D
Site 57
S526
T
E
I
S
L
K
D
S
T
L
D
N
_
_
_
Site 58
T527
E
I
S
L
K
D
S
T
L
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation