KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FBXO24
Full Name:
F-box only protein 24
Alias:
Type:
Mass (Da):
64889
Number AA:
580
UniProt ID:
O75426
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
R
R
R
R
V
K
R
S
C
P
S
C
G
S
E
Site 2
S20
R
V
K
R
S
C
P
S
C
G
S
E
L
G
V
Site 3
S38
R
G
K
G
N
P
I
S
I
Q
L
F
P
P
E
Site 4
Y68
A
L
G
Q
T
C
R
Y
F
H
E
V
C
D
G
Site 5
S87
R
R
I
C
R
R
L
S
P
R
L
Q
D
Q
G
Site 6
S95
P
R
L
Q
D
Q
G
S
G
V
R
P
W
K
R
Site 7
Y108
K
R
A
A
I
L
N
Y
T
K
G
L
Y
F
Q
Site 8
Y113
L
N
Y
T
K
G
L
Y
F
Q
A
F
G
G
R
Site 9
S125
G
G
R
R
R
C
L
S
K
S
V
A
P
L
L
Site 10
S127
R
R
R
C
L
S
K
S
V
A
P
L
L
A
H
Site 11
Y136
A
P
L
L
A
H
G
Y
R
R
F
L
P
T
K
Site 12
T142
G
Y
R
R
F
L
P
T
K
D
H
V
F
I
L
Site 13
Y177
Q
W
K
R
A
C
R
Y
V
V
L
C
R
G
A
Site 14
S189
R
G
A
K
D
F
A
S
D
P
R
C
D
T
V
Site 15
T195
A
S
D
P
R
C
D
T
V
Y
R
K
Y
L
Y
Site 16
Y197
D
P
R
C
D
T
V
Y
R
K
Y
L
Y
V
L
Site 17
Y200
C
D
T
V
Y
R
K
Y
L
Y
V
L
A
T
R
Site 18
Y202
T
V
Y
R
K
Y
L
Y
V
L
A
T
R
E
P
Site 19
T215
E
P
Q
E
V
V
G
T
T
S
S
R
A
C
D
Site 20
S217
Q
E
V
V
G
T
T
S
S
R
A
C
D
C
V
Site 21
Y227
A
C
D
C
V
E
V
Y
L
Q
S
S
G
Q
R
Site 22
T245
M
T
F
H
H
S
M
T
F
K
Q
I
V
L
V
Site 23
T264
Q
R
A
L
L
L
L
T
E
E
G
K
I
Y
S
Site 24
Y270
L
T
E
E
G
K
I
Y
S
L
V
V
N
E
T
Site 25
S271
T
E
E
G
K
I
Y
S
L
V
V
N
E
T
Q
Site 26
S284
T
Q
L
D
Q
P
R
S
Y
T
V
Q
L
A
L
Site 27
Y285
Q
L
D
Q
P
R
S
Y
T
V
Q
L
A
L
R
Site 28
T286
L
D
Q
P
R
S
Y
T
V
Q
L
A
L
R
K
Site 29
S295
Q
L
A
L
R
K
V
S
H
Y
L
P
H
L
R
Site 30
Y297
A
L
R
K
V
S
H
Y
L
P
H
L
R
V
A
Site 31
T307
H
L
R
V
A
C
M
T
S
N
Q
S
S
T
L
Site 32
S308
L
R
V
A
C
M
T
S
N
Q
S
S
T
L
Y
Site 33
S312
C
M
T
S
N
Q
S
S
T
L
Y
V
T
D
Q
Site 34
Y315
S
N
Q
S
S
T
L
Y
V
T
D
Q
G
G
V
Site 35
Y323
V
T
D
Q
G
G
V
Y
F
E
V
H
T
P
G
Site 36
T328
G
V
Y
F
E
V
H
T
P
G
V
Y
R
D
L
Site 37
Y332
E
V
H
T
P
G
V
Y
R
D
L
F
G
T
L
Site 38
Y386
F
M
Q
G
N
N
R
Y
G
Q
L
G
T
G
D
Site 39
T401
K
M
D
R
G
E
P
T
Q
V
C
Y
L
Q
R
Site 40
Y405
G
E
P
T
Q
V
C
Y
L
Q
R
P
I
T
L
Site 41
S423
L
N
H
S
L
V
L
S
Q
S
S
E
F
S
K
Site 42
S425
H
S
L
V
L
S
Q
S
S
E
F
S
K
E
L
Site 43
S429
L
S
Q
S
S
E
F
S
K
E
L
L
G
C
G
Site 44
S452
G
W
P
K
G
S
A
S
F
V
K
L
Q
V
K
Site 45
S478
R
E
C
L
Y
I
L
S
S
H
D
I
E
Q
H
Site 46
S494
P
Y
R
H
L
P
A
S
R
V
V
G
T
P
E
Site 47
T499
P
A
S
R
V
V
G
T
P
E
P
S
L
G
A
Site 48
Y522
M
A
Q
A
C
E
E
Y
L
S
Q
I
H
S
C
Site 49
S528
E
Y
L
S
Q
I
H
S
C
Q
T
L
Q
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation