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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DEAF-1
Full Name:
Deformed epidermal autoregulatory factor 1 homolog
Alias:
Nuclear DEAF-1-related transcriptional regulator;Suppressin;Zinc finger MYND domain-containing protein 5
Type:
Mass (Da):
59327
Number AA:
565
UniProt ID:
O75398
International Prot ID:
IPI00783411
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0009653
GO:0007281
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
D
S
D
S
A
A
K
Q
L
G
L
Site 2
S43
E
A
E
E
P
V
L
S
R
D
E
D
S
E
E
Site 3
S48
V
L
S
R
D
E
D
S
E
E
D
A
D
S
E
Site 4
S54
D
S
E
E
D
A
D
S
E
A
E
R
E
T
P
Site 5
T60
D
S
E
A
E
R
E
T
P
R
V
T
A
V
A
Site 6
S140
T
A
L
Q
I
G
D
S
L
N
T
E
K
A
T
Site 7
T160
T
D
G
S
I
V
E
T
T
G
L
K
G
P
A
Site 8
T171
K
G
P
A
A
P
L
T
P
G
P
Q
S
P
P
Site 9
S176
P
L
T
P
G
P
Q
S
P
P
T
P
L
A
P
Site 10
T179
P
G
P
Q
S
P
P
T
P
L
A
P
G
Q
E
Site 11
T190
P
G
Q
E
K
G
G
T
K
Y
N
W
D
P
S
Site 12
Y192
Q
E
K
G
G
T
K
Y
N
W
D
P
S
V
Y
Site 13
S197
T
K
Y
N
W
D
P
S
V
Y
D
S
E
L
P
Site 14
Y199
Y
N
W
D
P
S
V
Y
D
S
E
L
P
V
R
Site 15
S201
W
D
P
S
V
Y
D
S
E
L
P
V
R
C
R
Site 16
S211
P
V
R
C
R
N
I
S
G
T
L
Y
K
N
R
Site 17
T213
R
C
R
N
I
S
G
T
L
Y
K
N
R
L
G
Site 18
Y215
R
N
I
S
G
T
L
Y
K
N
R
L
G
S
G
Site 19
S221
L
Y
K
N
R
L
G
S
G
G
R
G
R
C
I
Site 20
S236
K
Q
G
E
N
W
Y
S
P
T
E
F
E
A
M
Site 21
S248
E
A
M
A
G
R
A
S
S
K
D
W
K
R
S
Site 22
S249
A
M
A
G
R
A
S
S
K
D
W
K
R
S
I
Site 23
S255
S
S
K
D
W
K
R
S
I
R
Y
A
G
R
P
Site 24
Y300
P
V
R
L
F
V
P
Y
K
R
R
K
K
E
N
Site 25
T312
K
E
N
E
L
P
T
T
P
V
K
K
D
S
P
Site 26
S318
T
T
P
V
K
K
D
S
P
K
N
I
T
L
L
Site 27
T323
K
D
S
P
K
N
I
T
L
L
P
A
T
A
A
Site 28
S344
P
S
G
Q
I
T
T
S
G
A
L
T
F
D
R
Site 29
S380
G
A
T
V
Q
E
A
S
V
Q
P
P
C
R
A
Site 30
S388
V
Q
P
P
C
R
A
S
H
P
E
P
H
Y
P
Site 31
Y394
A
S
H
P
E
P
H
Y
P
G
Y
Q
D
S
C
Site 32
Y397
P
E
P
H
Y
P
G
Y
Q
D
S
C
Q
I
A
Site 33
T421
S
H
P
K
I
V
L
T
S
L
P
A
L
A
V
Site 34
S422
H
P
K
I
V
L
T
S
L
P
A
L
A
V
P
Site 35
T432
A
L
A
V
P
P
P
T
P
T
K
A
A
P
P
Site 36
S448
L
V
N
G
L
E
L
S
E
P
R
S
W
L
Y
Site 37
S452
L
E
L
S
E
P
R
S
W
L
Y
L
E
E
M
Site 38
Y455
S
E
P
R
S
W
L
Y
L
E
E
M
V
N
S
Site 39
S462
Y
L
E
E
M
V
N
S
L
L
N
T
A
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation