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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF217
Full Name:
Zinc finger protein 217
Alias:
Z217; ZABC1; ZN217
Type:
Mass (Da):
115272
Number AA:
1048
UniProt ID:
O75362
International Prot ID:
IPI00025310
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000118
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0010843
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006351
GO:0006351
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
D
G
P
E
V
I
G
S
S
L
G
S
P
M
E
Site 2
S27
G
P
E
V
I
G
S
S
L
G
S
P
M
E
M
Site 3
S30
V
I
G
S
S
L
G
S
P
M
E
M
E
D
A
Site 4
T51
A
V
V
P
F
R
A
T
Q
E
K
N
V
I
Q
Site 5
T75
M
F
C
S
Q
T
F
T
H
S
E
D
L
N
K
Site 6
Y104
V
L
R
V
E
A
E
Y
L
S
P
L
D
K
S
Site 7
S106
R
V
E
A
E
Y
L
S
P
L
D
K
S
Q
V
Site 8
S111
Y
L
S
P
L
D
K
S
Q
V
R
T
E
P
P
Site 9
T115
L
D
K
S
Q
V
R
T
E
P
P
K
E
K
N
Site 10
T149
D
V
E
I
H
M
R
T
H
K
D
S
F
T
Y
Site 11
Y156
T
H
K
D
S
F
T
Y
G
C
N
M
C
G
R
Site 12
S182
M
R
T
H
N
G
K
S
G
A
R
S
K
L
Q
Site 13
S186
N
G
K
S
G
A
R
S
K
L
Q
Q
G
L
E
Site 14
S195
L
Q
Q
G
L
E
S
S
P
A
T
I
N
E
V
Site 15
S210
V
Q
V
H
A
A
E
S
I
S
S
P
Y
K
I
Site 16
T242
R
K
V
H
T
K
K
T
A
F
G
T
S
S
A
Site 17
S248
K
T
A
F
G
T
S
S
A
Q
T
D
S
P
Q
Site 18
T251
F
G
T
S
S
A
Q
T
D
S
P
Q
G
G
M
Site 19
S253
T
S
S
A
Q
T
D
S
P
Q
G
G
M
P
S
Site 20
S260
S
P
Q
G
G
M
P
S
S
R
E
D
F
L
Q
Site 21
S261
P
Q
G
G
M
P
S
S
R
E
D
F
L
Q
L
Site 22
S275
L
F
N
L
R
P
K
S
H
P
E
T
G
K
K
Site 23
T279
R
P
K
S
H
P
E
T
G
K
K
P
V
R
C
Site 24
T295
P
Q
L
D
P
F
T
T
F
Q
A
W
Q
L
A
Site 25
S316
I
C
Q
E
V
K
E
S
G
Q
E
G
S
T
D
Site 26
S321
K
E
S
G
Q
E
G
S
T
D
N
D
D
S
S
Site 27
T322
E
S
G
Q
E
G
S
T
D
N
D
D
S
S
S
Site 28
S327
G
S
T
D
N
D
D
S
S
S
E
K
E
L
G
Site 29
S328
S
T
D
N
D
D
S
S
S
E
K
E
L
G
E
Site 30
S329
T
D
N
D
D
S
S
S
E
K
E
L
G
E
T
Site 31
T336
S
E
K
E
L
G
E
T
N
K
G
S
C
A
G
Site 32
S340
L
G
E
T
N
K
G
S
C
A
G
L
S
Q
E
Site 33
S345
K
G
S
C
A
G
L
S
Q
E
K
E
K
C
K
Site 34
S354
E
K
E
K
C
K
H
S
H
G
E
A
P
S
V
Site 35
S369
D
A
D
P
K
L
P
S
S
K
E
K
P
T
H
Site 36
S370
A
D
P
K
L
P
S
S
K
E
K
P
T
H
C
Site 37
S378
K
E
K
P
T
H
C
S
E
C
G
K
A
F
R
Site 38
Y387
C
G
K
A
F
R
T
Y
H
Q
L
V
L
H
S
Site 39
S407
D
R
R
A
G
A
E
S
P
T
M
S
V
D
G
Site 40
S411
G
A
E
S
P
T
M
S
V
D
G
R
Q
P
G
Site 41
T419
V
D
G
R
Q
P
G
T
C
S
P
D
L
A
A
Site 42
S421
G
R
Q
P
G
T
C
S
P
D
L
A
A
P
L
Site 43
S441
V
D
R
G
E
G
G
S
E
D
G
S
E
D
G
Site 44
S445
E
G
G
S
E
D
G
S
E
D
G
L
P
E
G
Site 45
T468
G
G
K
I
K
H
L
T
S
S
R
E
C
S
Y
Site 46
S469
G
K
I
K
H
L
T
S
S
R
E
C
S
Y
C
Site 47
S470
K
I
K
H
L
T
S
S
R
E
C
S
Y
C
G
Site 48
S474
L
T
S
S
R
E
C
S
Y
C
G
K
F
F
R
Site 49
Y484
G
K
F
F
R
S
N
Y
Y
L
N
I
H
L
R
Site 50
Y485
K
F
F
R
S
N
Y
Y
L
N
I
H
L
R
T
Site 51
T492
Y
L
N
I
H
L
R
T
H
T
G
E
K
P
Y
Site 52
T494
N
I
H
L
R
T
H
T
G
E
K
P
Y
K
C
Site 53
Y506
Y
K
C
E
F
C
E
Y
A
A
A
Q
K
T
S
Site 54
S513
Y
A
A
A
Q
K
T
S
L
R
Y
H
L
E
R
Site 55
T542
N
D
G
K
N
Q
D
T
E
D
A
L
L
T
A
Site 56
S551
D
A
L
L
T
A
D
S
A
Q
T
K
N
L
K
Site 57
T568
F
D
G
A
K
D
V
T
G
S
P
P
A
K
Q
Site 58
S570
G
A
K
D
V
T
G
S
P
P
A
K
Q
L
K
Site 59
S581
K
Q
L
K
E
M
P
S
V
F
Q
N
V
L
G
Site 60
S593
V
L
G
S
A
V
L
S
P
A
H
K
D
T
Q
Site 61
T599
L
S
P
A
H
K
D
T
Q
D
F
H
K
N
A
Site 62
T619
D
K
V
N
K
N
P
T
P
A
Y
L
D
L
L
Site 63
Y622
N
K
N
P
T
P
A
Y
L
D
L
L
K
K
R
Site 64
S630
L
D
L
L
K
K
R
S
A
V
E
T
Q
A
N
Site 65
T634
K
K
R
S
A
V
E
T
Q
A
N
N
L
I
C
Site 66
T648
C
R
T
K
A
D
V
T
P
P
P
D
G
S
T
Site 67
S654
V
T
P
P
P
D
G
S
T
T
H
N
L
E
V
Site 68
S662
T
T
H
N
L
E
V
S
P
K
E
K
Q
T
E
Site 69
Y676
E
T
A
A
D
C
R
Y
R
P
S
V
D
C
H
Site 70
S679
A
D
C
R
Y
R
P
S
V
D
C
H
E
K
P
Site 71
S690
H
E
K
P
L
N
L
S
V
G
A
L
H
N
C
Site 72
Y735
H
Q
R
L
E
H
K
Y
N
P
D
V
H
K
N
Site 73
S747
H
K
N
C
R
N
K
S
L
L
R
S
R
R
T
Site 74
S751
R
N
K
S
L
L
R
S
R
R
T
G
C
P
P
Site 75
T754
S
L
L
R
S
R
R
T
G
C
P
P
A
L
L
Site 76
S769
G
K
D
V
P
P
L
S
S
F
C
K
P
K
P
Site 77
S770
K
D
V
P
P
L
S
S
F
C
K
P
K
P
K
Site 78
S778
F
C
K
P
K
P
K
S
A
F
P
A
Q
S
K
Site 79
S784
K
S
A
F
P
A
Q
S
K
S
L
P
S
A
K
Site 80
S786
A
F
P
A
Q
S
K
S
L
P
S
A
K
G
K
Site 81
S789
A
Q
S
K
S
L
P
S
A
K
G
K
Q
S
P
Site 82
S795
P
S
A
K
G
K
Q
S
P
P
G
P
G
K
A
Site 83
T805
G
P
G
K
A
P
L
T
S
G
I
D
S
S
T
Site 84
S806
P
G
K
A
P
L
T
S
G
I
D
S
S
T
L
Site 85
S810
P
L
T
S
G
I
D
S
S
T
L
A
P
S
N
Site 86
T812
T
S
G
I
D
S
S
T
L
A
P
S
N
L
K
Site 87
S816
D
S
S
T
L
A
P
S
N
L
K
S
H
R
P
Site 88
S820
L
A
P
S
N
L
K
S
H
R
P
Q
Q
N
V
Site 89
S839
A
A
T
R
Q
Q
Q
S
E
M
F
P
K
T
S
Site 90
T845
Q
S
E
M
F
P
K
T
S
V
S
P
A
P
D
Site 91
S846
S
E
M
F
P
K
T
S
V
S
P
A
P
D
K
Site 92
S848
M
F
P
K
T
S
V
S
P
A
P
D
K
T
K
Site 93
T854
V
S
P
A
P
D
K
T
K
R
P
E
T
K
L
Site 94
T859
D
K
T
K
R
P
E
T
K
L
K
P
L
P
V
Site 95
S869
K
P
L
P
V
A
P
S
Q
P
T
L
G
S
S
Site 96
T872
P
V
A
P
S
Q
P
T
L
G
S
S
N
I
N
Site 97
S875
P
S
Q
P
T
L
G
S
S
N
I
N
G
S
I
Site 98
S876
S
Q
P
T
L
G
S
S
N
I
N
G
S
I
D
Site 99
S881
G
S
S
N
I
N
G
S
I
D
Y
P
A
K
N
Site 100
Y884
N
I
N
G
S
I
D
Y
P
A
K
N
D
S
P
Site 101
S890
D
Y
P
A
K
N
D
S
P
W
A
P
P
G
R
Site 102
Y899
W
A
P
P
G
R
D
Y
F
C
N
R
S
A
S
Site 103
S906
Y
F
C
N
R
S
A
S
N
T
A
A
E
F
G
Site 104
T908
C
N
R
S
A
S
N
T
A
A
E
F
G
E
P
Site 105
Y940
G
A
N
Y
R
R
G
Y
D
L
P
K
Y
H
M
Site 106
Y945
R
G
Y
D
L
P
K
Y
H
M
V
R
G
I
T
Site 107
T952
Y
H
M
V
R
G
I
T
S
L
L
P
Q
D
C
Site 108
Y961
L
L
P
Q
D
C
V
Y
P
S
Q
A
L
P
P
Site 109
S963
P
Q
D
C
V
Y
P
S
Q
A
L
P
P
K
P
Site 110
S974
P
P
K
P
R
F
L
S
S
S
E
V
D
S
P
Site 111
S975
P
K
P
R
F
L
S
S
S
E
V
D
S
P
N
Site 112
S976
K
P
R
F
L
S
S
S
E
V
D
S
P
N
V
Site 113
S980
L
S
S
S
E
V
D
S
P
N
V
L
T
V
Q
Site 114
T985
V
D
S
P
N
V
L
T
V
Q
K
P
Y
G
G
Site 115
S1007
V
P
A
G
S
P
A
S
S
S
T
L
E
G
K
Site 116
S1008
P
A
G
S
P
A
S
S
S
T
L
E
G
K
R
Site 117
S1009
A
G
S
P
A
S
S
S
T
L
E
G
K
R
P
Site 118
T1010
G
S
P
A
S
S
S
T
L
E
G
K
R
P
V
Site 119
S1018
L
E
G
K
R
P
V
S
Y
Q
H
L
S
N
S
Site 120
Y1019
E
G
K
R
P
V
S
Y
Q
H
L
S
N
S
M
Site 121
S1023
P
V
S
Y
Q
H
L
S
N
S
M
A
Q
K
R
Site 122
S1025
S
Y
Q
H
L
S
N
S
M
A
Q
K
R
N
Y
Site 123
Y1032
S
M
A
Q
K
R
N
Y
E
N
F
I
G
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation