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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBX10
Full Name:
T-box transcription factor TBX10
Alias:
T-box 10; T-box 7; TBX13; TBX7
Type:
Nucleus protein
Mass (Da):
42341
Number AA:
385
UniProt ID:
O75333
International Prot ID:
IPI00385367
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0009653
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
I
L
A
P
S
E
T
Y
P
L
P
T
T
S
S
Site 2
T23
E
T
Y
P
L
P
T
T
S
S
G
W
E
P
R
Site 3
S25
Y
P
L
P
T
T
S
S
G
W
E
P
R
L
G
Site 4
S33
G
W
E
P
R
L
G
S
P
F
P
S
G
P
C
Site 5
S37
R
L
G
S
P
F
P
S
G
P
C
T
S
S
T
Site 6
T41
P
F
P
S
G
P
C
T
S
S
T
G
A
Q
A
Site 7
S63
G
P
K
N
P
R
V
S
R
V
T
V
Q
L
E
Site 8
T66
N
P
R
V
S
R
V
T
V
Q
L
E
M
K
P
Site 9
Y111
G
M
D
S
L
A
D
Y
A
L
L
M
D
F
I
Site 10
Y125
I
P
L
D
D
K
R
Y
R
Y
A
F
H
S
S
Site 11
Y127
L
D
D
K
R
Y
R
Y
A
F
H
S
S
A
W
Site 12
S131
R
Y
R
Y
A
F
H
S
S
A
W
L
V
A
G
Site 13
T144
A
G
K
A
D
P
A
T
P
G
R
V
H
F
H
Site 14
S154
R
V
H
F
H
P
D
S
P
A
K
G
A
Q
W
Site 15
Y192
I
L
N
S
M
H
R
Y
Q
P
R
F
H
V
V
Site 16
S207
F
V
D
P
R
K
D
S
E
R
Y
A
Q
E
N
Site 17
Y210
P
R
K
D
S
E
R
Y
A
Q
E
N
F
K
S
Site 18
T226
I
F
T
E
T
Q
F
T
A
V
T
A
Y
Q
N
Site 19
Y231
Q
F
T
A
V
T
A
Y
Q
N
H
R
I
T
Q
Site 20
T237
A
Y
Q
N
H
R
I
T
Q
L
K
I
A
S
N
Site 21
S253
F
A
K
G
F
R
E
S
D
L
D
S
W
P
V
Site 22
S257
F
R
E
S
D
L
D
S
W
P
V
A
P
R
P
Site 23
S267
V
A
P
R
P
L
L
S
V
P
A
R
S
H
S
Site 24
S275
V
P
A
R
S
H
S
S
L
S
P
C
V
L
K
Site 25
S277
A
R
S
H
S
S
L
S
P
C
V
L
K
G
A
Site 26
S295
E
K
D
P
N
K
A
S
A
S
T
S
K
T
P
Site 27
S297
D
P
N
K
A
S
A
S
T
S
K
T
P
A
W
Site 28
S299
N
K
A
S
A
S
T
S
K
T
P
A
W
L
H
Site 29
T301
A
S
A
S
T
S
K
T
P
A
W
L
H
H
Q
Site 30
T326
P
A
T
Y
R
P
V
T
Y
Q
S
L
Y
S
G
Site 31
Y327
A
T
Y
R
P
V
T
Y
Q
S
L
Y
S
G
A
Site 32
S329
Y
R
P
V
T
Y
Q
S
L
Y
S
G
A
P
S
Site 33
Y331
P
V
T
Y
Q
S
L
Y
S
G
A
P
S
H
L
Site 34
S332
V
T
Y
Q
S
L
Y
S
G
A
P
S
H
L
G
Site 35
S336
S
L
Y
S
G
A
P
S
H
L
G
I
P
R
T
Site 36
T343
S
H
L
G
I
P
R
T
R
P
A
P
Y
P
L
Site 37
Y348
P
R
T
R
P
A
P
Y
P
L
P
N
I
R
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation