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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEMA7A
Full Name:
Semaphorin-7A
Alias:
CDw108;JMH blood group antigen;John-Milton-Hargen human blood group Ag;Semaphorin-K1;Semaphorin-L
Type:
Mass (Da):
74824
Number AA:
666
UniProt ID:
O75326
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
P
P
G
R
A
A
P
S
A
P
R
A
R
V
P
Site 2
S50
S
A
Q
G
H
L
R
S
G
P
R
I
F
A
V
Site 3
T76
F
G
Q
T
E
P
H
T
V
L
F
H
E
P
G
Site 4
S85
L
F
H
E
P
G
S
S
S
V
W
V
G
G
R
Site 5
S86
F
H
E
P
G
S
S
S
V
W
V
G
G
R
G
Site 6
Y96
V
G
G
R
G
K
V
Y
L
F
D
F
P
E
G
Site 7
S107
F
P
E
G
K
N
A
S
V
R
T
V
N
I
G
Site 8
T110
G
K
N
A
S
V
R
T
V
N
I
G
S
T
K
Site 9
S115
V
R
T
V
N
I
G
S
T
K
G
S
C
L
D
Site 10
S119
N
I
G
S
T
K
G
S
C
L
D
K
R
D
C
Site 11
Y129
D
K
R
D
C
E
N
Y
I
T
L
L
E
R
R
Site 12
T131
R
D
C
E
N
Y
I
T
L
L
E
R
R
S
E
Site 13
T145
E
G
L
L
A
C
G
T
N
A
R
H
P
S
C
Site 14
Y169
P
L
G
E
M
R
G
Y
A
P
F
S
P
D
E
Site 15
S173
M
R
G
Y
A
P
F
S
P
D
E
N
S
L
V
Site 16
S178
P
F
S
P
D
E
N
S
L
V
L
F
E
G
D
Site 17
Y188
L
F
E
G
D
E
V
Y
S
T
I
R
K
Q
E
Site 18
S189
F
E
G
D
E
V
Y
S
T
I
R
K
Q
E
Y
Site 19
T190
E
G
D
E
V
Y
S
T
I
R
K
Q
E
Y
N
Site 20
Y196
S
T
I
R
K
Q
E
Y
N
G
K
I
P
R
F
Site 21
S210
F
R
R
I
R
G
E
S
E
L
Y
T
S
D
T
Site 22
Y213
I
R
G
E
S
E
L
Y
T
S
D
T
V
M
Q
Site 23
T214
R
G
E
S
E
L
Y
T
S
D
T
V
M
Q
N
Site 24
S215
G
E
S
E
L
Y
T
S
D
T
V
M
Q
N
P
Site 25
T217
S
E
L
Y
T
S
D
T
V
M
Q
N
P
Q
F
Site 26
Y236
I
V
H
Q
D
Q
A
Y
D
D
K
I
Y
Y
F
Site 27
Y241
Q
A
Y
D
D
K
I
Y
Y
F
F
R
E
D
N
Site 28
Y242
A
Y
D
D
K
I
Y
Y
F
F
R
E
D
N
P
Site 29
S274
R
G
D
Q
G
G
E
S
S
L
S
V
S
K
W
Site 30
S275
G
D
Q
G
G
E
S
S
L
S
V
S
K
W
N
Site 31
S277
Q
G
G
E
S
S
L
S
V
S
K
W
N
T
F
Site 32
S279
G
E
S
S
L
S
V
S
K
W
N
T
F
L
K
Site 33
T296
L
V
C
S
D
A
A
T
N
K
N
F
N
R
L
Site 34
S313
V
F
L
L
P
D
P
S
G
Q
W
R
D
T
R
Site 35
T319
P
S
G
Q
W
R
D
T
R
V
Y
G
V
F
S
Site 36
Y322
Q
W
R
D
T
R
V
Y
G
V
F
S
N
P
W
Site 37
S349
I
D
K
V
F
R
T
S
S
L
K
G
Y
H
S
Site 38
S350
D
K
V
F
R
T
S
S
L
K
G
Y
H
S
S
Site 39
Y354
R
T
S
S
L
K
G
Y
H
S
S
L
P
N
P
Site 40
S356
S
S
L
K
G
Y
H
S
S
L
P
N
P
R
P
Site 41
S357
S
L
K
G
Y
H
S
S
L
P
N
P
R
P
G
Site 42
T377
Q
Q
P
I
P
T
E
T
F
Q
V
A
D
R
H
Site 43
T399
E
P
M
G
P
L
K
T
P
L
F
H
S
K
Y
Site 44
Y406
T
P
L
F
H
S
K
Y
H
Y
Q
K
V
A
V
Site 45
Y408
L
F
H
S
K
Y
H
Y
Q
K
V
A
V
H
R
Site 46
T423
M
Q
A
S
H
G
E
T
F
H
V
L
Y
L
T
Site 47
Y428
G
E
T
F
H
V
L
Y
L
T
T
D
R
G
T
Site 48
T430
T
F
H
V
L
Y
L
T
T
D
R
G
T
I
H
Site 49
T431
F
H
V
L
Y
L
T
T
D
R
G
T
I
H
K
Site 50
T435
Y
L
T
T
D
R
G
T
I
H
K
V
V
E
P
Site 51
S448
E
P
G
E
Q
E
H
S
F
A
F
N
I
M
E
Site 52
S469
A
A
A
I
Q
T
M
S
L
D
A
E
R
R
K
Site 53
Y478
D
A
E
R
R
K
L
Y
V
S
S
Q
W
E
V
Site 54
S480
E
R
R
K
L
Y
V
S
S
Q
W
E
V
S
Q
Site 55
S481
R
R
K
L
Y
V
S
S
Q
W
E
V
S
Q
V
Site 56
Y510
C
L
M
S
R
D
P
Y
C
G
W
D
Q
G
R
Site 57
S520
W
D
Q
G
R
C
I
S
I
Y
S
S
E
R
S
Site 58
Y522
Q
G
R
C
I
S
I
Y
S
S
E
R
S
V
L
Site 59
S523
G
R
C
I
S
I
Y
S
S
E
R
S
V
L
Q
Site 60
S524
R
C
I
S
I
Y
S
S
E
R
S
V
L
Q
S
Site 61
S527
S
I
Y
S
S
E
R
S
V
L
Q
S
I
N
P
Site 62
S531
S
E
R
S
V
L
Q
S
I
N
P
A
E
P
H
Site 63
S555
K
A
P
L
Q
K
V
S
L
A
P
N
S
R
Y
Site 64
S560
K
V
S
L
A
P
N
S
R
Y
Y
L
S
C
P
Site 65
Y562
S
L
A
P
N
S
R
Y
Y
L
S
C
P
M
E
Site 66
Y563
L
A
P
N
S
R
Y
Y
L
S
C
P
M
E
S
Site 67
S565
P
N
S
R
Y
Y
L
S
C
P
M
E
S
R
H
Site 68
T574
P
M
E
S
R
H
A
T
Y
S
W
R
H
K
E
Site 69
S576
E
S
R
H
A
T
Y
S
W
R
H
K
E
N
V
Site 70
S586
H
K
E
N
V
E
Q
S
C
E
P
G
H
Q
S
Site 71
Y608
E
N
L
T
A
Q
Q
Y
G
H
Y
F
C
E
A
Site 72
Y611
T
A
Q
Q
Y
G
H
Y
F
C
E
A
Q
E
G
Site 73
Y620
C
E
A
Q
E
G
S
Y
F
R
E
A
Q
H
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation