PhosphoNET

           
Protein Info 
   
Short Name:  LRP5
Full Name:  Low-density lipoprotein receptor-related protein 5
Alias:  BMND1; EVR1; HBM; low density lipoprotein receptor-related pr; low density lipoprotein receptor-related protein 5; low-density lipoprotein receptor-related 5; LR3; LRP7; OPPG; OPS; VBCH2
Type:  Receptor, misc.
Mass (Da):  179145
Number AA:  1615
UniProt ID:  O75197
International Prot ID:  IPI00307298
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0004872     PhosphoSite+ KinaseNET
Biological Process:  GO:0016055  GO:0006897  GO:0006629 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y1080VVNAERGYLYFTNMQ
Site 2Y1082NAERGYLYFTNMQDR
Site 3Y1426NGPFPHEYVSGTPHV
Site 4S1428PFPHEYVSGTPHVPL
Site 5T1430PHEYVSGTPHVPLNF
Site 6S1443NFIAPGGSQHGPFTG
Site 7T1449GSQHGPFTGIACGKS
Site 8S1460CGKSMMSSVSLMGGR
Site 9S1462KSMMSSVSLMGGRGG
Site 10Y1473GRGGVPLYDRNHVTG
Site 11T1479LYDRNHVTGASSSSS
Site 12S1482RNHVTGASSSSSSST
Site 13S1483NHVTGASSSSSSSTK
Site 14S1484HVTGASSSSSSSTKA
Site 15S1485VTGASSSSSSSTKAT
Site 16S1486TGASSSSSSSTKATL
Site 17S1487GASSSSSSSTKATLY
Site 18S1488ASSSSSSSTKATLYP
Site 19T1489SSSSSSSTKATLYPP
Site 20T1492SSSSTKATLYPPILN
Site 21Y1494SSTKATLYPPILNPP
Site 22S1503PILNPPPSPATDPSL
Site 23T1506NPPPSPATDPSLYNM
Site 24S1509PSPATDPSLYNMDMF
Site 25Y1511PATDPSLYNMDMFYS
Site 26Y1517LYNMDMFYSSNIPAT
Site 27T1524YSSNIPATARPYRPY
Site 28Y1528IPATARPYRPYIIRG
Site 29Y1531TARPYRPYIIRGMAP
Site 30T1540IRGMAPPTTPCSTDV
Site 31T1541RGMAPPTTPCSTDVC
Site 32S1544APPTTPCSTDVCDSD
Site 33S1550CSTDVCDSDYSASRW
Site 34Y1552TDVCDSDYSASRWKA
Site 35S1553DVCDSDYSASRWKAS
Site 36Y1562SRWKASKYYLDLNSD
Site 37Y1563RWKASKYYLDLNSDS
Site 38S1568KYYLDLNSDSDPYPP
Site 39S1570YLDLNSDSDPYPPPP
Site 40Y1573LNSDSDPYPPPPTPH
Site 41T1578DPYPPPPTPHSQYLS
Site 42S1581PPPPTPHSQYLSAED
Site 43Y1583PPTPHSQYLSAEDSC
Site 44S1585TPHSQYLSAEDSCPP
Site 45S1589QYLSAEDSCPPSPAT
Site 46S1593AEDSCPPSPATERSY
Site 47T1596SCPPSPATERSYFHL
Site 48S1599PSPATERSYFHLFPP
Site 49Y1600SPATERSYFHLFPPP
Site 50S1609HLFPPPPSPCTDSS_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation