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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP2C2
Full Name:
Calcium-transporting ATPase type 2C member 2
Alias:
AT2C2; ATPase 2C2; ATPase, Ca++ transporting, type 2C, 2; ATPase, Ca++ transporting, type 2C, member 2; DKFZp686H22230; KIAA0703; SPCA2
Type:
EC 3.6.3.8; Transporter; Hydrolase
Mass (Da):
103190
Number AA:
UniProt ID:
O75185
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0005388
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0006816
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
V
E
G
R
V
S
E
F
L
K
K
L
G
Site 2
Y22
F
S
G
G
G
R
Q
Y
Q
A
L
E
K
D
E
Site 3
S38
E
A
L
I
D
E
Q
S
E
L
K
A
I
E
K
Site 4
T50
I
E
K
E
K
K
V
T
A
L
P
P
K
E
A
Site 5
S78
V
D
L
H
T
G
L
S
E
F
S
V
T
Q
R
Site 6
S81
H
T
G
L
S
E
F
S
V
T
Q
R
R
L
A
Site 7
T83
G
L
S
E
F
S
V
T
Q
R
R
L
A
H
G
Site 8
Y106
S
E
P
V
W
K
K
Y
L
D
Q
F
K
N
P
Site 9
T146
T
A
V
L
V
V
V
T
V
A
F
I
Q
E
Y
Site 10
Y153
T
V
A
F
I
Q
E
Y
R
S
E
K
S
L
E
Site 11
S155
A
F
I
Q
E
Y
R
S
E
K
S
L
E
E
L
Site 12
S158
Q
E
Y
R
S
E
K
S
L
E
E
L
T
K
M
Site 13
T210
D
I
R
L
T
E
V
T
D
L
L
V
D
E
S
Site 14
S217
T
D
L
L
V
D
E
S
S
F
T
G
E
A
E
Site 15
S218
D
L
L
V
D
E
S
S
F
T
G
E
A
E
P
Site 16
T220
L
V
D
E
S
S
F
T
G
E
A
E
P
C
S
Site 17
S227
T
G
E
A
E
P
C
S
K
T
D
S
P
L
T
Site 18
T229
E
A
E
P
C
S
K
T
D
S
P
L
T
G
G
Site 19
S231
E
P
C
S
K
T
D
S
P
L
T
G
G
G
D
Site 20
T234
S
K
T
D
S
P
L
T
G
G
G
D
L
T
T
Site 21
T264
G
Q
G
V
V
I
G
T
G
E
S
S
Q
F
G
Site 22
S267
V
V
I
G
T
G
E
S
S
Q
F
G
E
V
F
Site 23
S268
V
I
G
T
G
E
S
S
Q
F
G
E
V
F
K
Site 24
T282
K
M
M
Q
A
E
E
T
P
K
T
P
L
Q
K
Site 25
T285
Q
A
E
E
T
P
K
T
P
L
Q
K
S
M
D
Site 26
S290
P
K
T
P
L
Q
K
S
M
D
R
L
G
K
Q
Site 27
T381
S
V
L
C
S
D
K
T
G
T
L
T
A
N
E
Site 28
T392
T
A
N
E
M
T
V
T
Q
L
V
T
S
D
G
Site 29
S405
D
G
L
R
A
E
V
S
G
V
G
Y
D
G
Q
Site 30
T457
N
A
V
M
G
Q
P
T
E
G
A
L
M
A
L
Site 31
S471
L
A
M
K
M
D
L
S
D
I
K
N
S
Y
I
Site 32
Y477
L
S
D
I
K
N
S
Y
I
R
K
K
E
I
P
Site 33
S486
R
K
K
E
I
P
F
S
S
E
Q
K
W
M
A
Site 34
S487
K
K
E
I
P
F
S
S
E
Q
K
W
M
A
V
Site 35
Y507
T
E
D
Q
E
D
I
Y
F
M
K
G
A
L
E
Site 36
Y519
A
L
E
E
V
I
R
Y
C
T
M
Y
N
N
G
Site 37
T533
G
G
I
P
L
P
L
T
P
Q
Q
R
S
F
C
Site 38
S538
P
L
T
P
Q
Q
R
S
F
C
L
Q
E
E
K
Site 39
S549
Q
E
E
K
R
M
G
S
L
G
L
R
V
L
A
Site 40
S590
K
E
A
V
Q
V
L
S
E
S
G
V
S
V
K
Site 41
S625
N
G
K
L
Q
A
M
S
G
E
E
V
D
S
V
Site 42
S631
M
S
G
E
E
V
D
S
V
E
K
G
E
L
A
Site 43
S645
A
D
R
V
G
K
V
S
V
F
F
R
T
S
P
Site 44
S651
V
S
V
F
F
R
T
S
P
K
H
K
L
K
I
Site 45
S699
G
Q
T
G
T
D
V
S
K
E
A
A
N
M
I
Site 46
Y727
E
E
G
K
G
I
F
Y
N
I
K
N
F
V
R
Site 47
S778
M
D
G
P
P
A
Q
S
L
G
V
E
P
V
D
Site 48
S795
A
F
R
Q
P
P
R
S
V
R
D
T
I
L
S
Site 49
T799
P
P
R
S
V
R
D
T
I
L
S
R
A
L
I
Site 50
S834
E
M
P
E
D
R
A
S
T
P
R
T
T
T
M
Site 51
T835
M
P
E
D
R
A
S
T
P
R
T
T
T
M
T
Site 52
T838
D
R
A
S
T
P
R
T
T
T
M
T
F
T
C
Site 53
T839
R
A
S
T
P
R
T
T
T
M
T
F
T
C
F
Site 54
T856
F
D
L
F
N
A
L
T
C
R
S
Q
T
K
L
Site 55
Y932
L
L
K
L
C
E
K
Y
C
C
S
P
K
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation