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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR1
Full Name:
WD repeat-containing protein 1
Alias:
WD repeat-containing protein 1
Type:
Mass (Da):
66176
Number AA:
606
UniProt ID:
O75083
International Prot ID:
IPI00873622
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0003008
GO:0007600
GO:0007605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
I
K
K
V
F
A
S
L
P
Q
V
E
R
G
Site 2
S20
P
Q
V
E
R
G
V
S
K
I
I
G
G
D
P
Site 3
Y34
P
K
G
N
N
F
L
Y
T
N
G
K
C
V
I
Site 4
Y54
N
P
A
L
A
D
I
Y
T
E
H
A
H
Q
V
Site 5
Y72
K
Y
A
P
S
G
F
Y
I
A
S
G
D
V
S
Site 6
S79
Y
I
A
S
G
D
V
S
G
K
L
R
I
W
D
Site 7
T87
G
K
L
R
I
W
D
T
T
Q
K
E
H
L
L
Site 8
T88
K
L
R
I
W
D
T
T
Q
K
E
H
L
L
K
Site 9
Y96
Q
K
E
H
L
L
K
Y
E
Y
Q
P
F
A
G
Site 10
Y98
E
H
L
L
K
Y
E
Y
Q
P
F
A
G
K
I
Site 11
S114
D
I
A
W
T
E
D
S
K
R
I
A
V
V
G
Site 12
S138
F
L
W
D
S
G
S
S
V
G
E
I
T
G
H
Site 13
Y160
D
I
K
Q
S
R
P
Y
R
L
A
T
G
S
D
Site 14
T164
S
R
P
Y
R
L
A
T
G
S
D
D
N
C
A
Site 15
S166
P
Y
R
L
A
T
G
S
D
D
N
C
A
A
F
Site 16
T184
P
P
F
K
F
K
F
T
I
G
D
H
S
R
F
Site 17
S198
F
V
N
C
V
R
F
S
P
D
G
N
R
F
A
Site 18
T206
P
D
G
N
R
F
A
T
A
S
A
D
G
Q
I
Site 19
S208
G
N
R
F
A
T
A
S
A
D
G
Q
I
Y
I
Site 20
Y214
A
S
A
D
G
Q
I
Y
I
Y
D
G
K
T
G
Site 21
Y216
A
D
G
Q
I
Y
I
Y
D
G
K
T
G
E
K
Site 22
Y238
K
A
H
D
G
G
I
Y
A
I
S
W
S
P
D
Site 23
S241
D
G
G
I
Y
A
I
S
W
S
P
D
S
T
H
Site 24
S246
A
I
S
W
S
P
D
S
T
H
L
L
S
A
S
Site 25
T247
I
S
W
S
P
D
S
T
H
L
L
S
A
S
G
Site 26
S251
P
D
S
T
H
L
L
S
A
S
G
D
K
T
S
Site 27
S253
S
T
H
L
L
S
A
S
G
D
K
T
S
K
I
Site 28
T257
L
S
A
S
G
D
K
T
S
K
I
W
D
V
S
Site 29
S258
S
A
S
G
D
K
T
S
K
I
W
D
V
S
V
Site 30
S294
W
Q
K
D
H
L
L
S
V
S
L
S
G
Y
I
Site 31
S296
K
D
H
L
L
S
V
S
L
S
G
Y
I
N
Y
Site 32
Y300
L
S
V
S
L
S
G
Y
I
N
Y
L
D
R
N
Site 33
Y303
S
L
S
G
Y
I
N
Y
L
D
R
N
N
P
S
Site 34
T327
S
K
S
I
Q
C
L
T
V
H
K
N
G
G
K
Site 35
S335
V
H
K
N
G
G
K
S
Y
I
Y
S
G
S
H
Site 36
Y336
H
K
N
G
G
K
S
Y
I
Y
S
G
S
H
D
Site 37
Y338
N
G
G
K
S
Y
I
Y
S
G
S
H
D
G
H
Site 38
S339
G
G
K
S
Y
I
Y
S
G
S
H
D
G
H
I
Site 39
Y348
S
H
D
G
H
I
N
Y
W
D
S
E
T
G
E
Site 40
T353
I
N
Y
W
D
S
E
T
G
E
N
D
S
F
A
Site 41
S358
S
E
T
G
E
N
D
S
F
A
G
K
G
H
T
Site 42
T372
T
N
Q
V
S
R
M
T
V
D
E
S
G
Q
L
Site 43
S376
S
R
M
T
V
D
E
S
G
Q
L
I
S
C
S
Site 44
S381
D
E
S
G
Q
L
I
S
C
S
M
D
D
T
V
Site 45
S383
S
G
Q
L
I
S
C
S
M
D
D
T
V
R
Y
Site 46
T387
I
S
C
S
M
D
D
T
V
R
Y
T
S
L
M
Site 47
Y390
S
M
D
D
T
V
R
Y
T
S
L
M
L
R
D
Site 48
T391
M
D
D
T
V
R
Y
T
S
L
M
L
R
D
Y
Site 49
S392
D
D
T
V
R
Y
T
S
L
M
L
R
D
Y
S
Site 50
Y398
T
S
L
M
L
R
D
Y
S
G
Q
G
V
V
K
Site 51
S399
S
L
M
L
R
D
Y
S
G
Q
G
V
V
K
L
Site 52
Y472
V
D
G
N
V
R
L
Y
S
I
L
G
T
T
L
Site 53
S473
D
G
N
V
R
L
Y
S
I
L
G
T
T
L
K
Site 54
T477
R
L
Y
S
I
L
G
T
T
L
K
D
E
G
K
Site 55
T493
L
E
A
K
G
P
V
T
D
V
A
Y
S
H
D
Site 56
Y522
V
F
S
V
A
D
G
Y
S
E
N
N
V
F
Y
Site 57
S562
M
V
Y
V
W
T
L
S
D
P
E
T
R
V
K
Site 58
T566
W
T
L
S
D
P
E
T
R
V
K
I
Q
D
A
Site 59
S580
A
H
R
L
H
H
V
S
S
L
A
W
L
D
E
Site 60
S581
H
R
L
H
H
V
S
S
L
A
W
L
D
E
H
Site 61
T589
L
A
W
L
D
E
H
T
L
V
T
T
S
H
D
Site 62
S594
E
H
T
L
V
T
T
S
H
D
A
S
V
K
E
Site 63
S598
V
T
T
S
H
D
A
S
V
K
E
W
T
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation