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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FCMD
Full Name:
Fukutin
Alias:
FKTN; Fukuyama-type congenital muscular dystrophy; LGMD2M
Type:
Endoplasmic reticulum; Transferase; EC 2.-.-.-
Mass (Da):
53724
Number AA:
461
UniProt ID:
O75072
International Prot ID:
IPI00306835
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005615
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0007517
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
L
L
F
Q
L
Y
Y
Y
K
H
Y
L
S
T
K
Site 2
Y31
Q
L
Y
Y
Y
K
H
Y
L
S
T
K
N
G
A
Site 3
S33
Y
Y
Y
K
H
Y
L
S
T
K
N
G
A
G
L
Site 4
S41
T
K
N
G
A
G
L
S
K
S
K
G
S
R
I
Site 5
S43
N
G
A
G
L
S
K
S
K
G
S
R
I
G
F
Site 6
S52
G
S
R
I
G
F
D
S
T
Q
W
R
A
V
K
Site 7
T53
S
R
I
G
F
D
S
T
Q
W
R
A
V
K
K
Site 8
S97
V
K
N
T
S
H
G
S
T
S
Q
C
K
F
F
Site 9
S152
P
R
L
D
G
I
D
S
L
S
G
T
E
I
P
Site 10
S154
L
D
G
I
D
S
L
S
G
T
E
I
P
L
H
Site 11
Y183
F
H
E
R
S
G
N
Y
L
W
H
G
H
L
R
Site 12
Y210
R
K
L
Q
F
G
R
Y
P
G
A
F
D
R
P
Site 13
T223
R
P
E
L
Q
Q
V
T
V
D
G
L
E
V
L
Site 14
Y252
S
R
F
I
E
C
R
Y
K
E
A
R
A
F
F
Site 15
Y262
A
R
A
F
F
Q
Q
Y
L
D
D
N
T
V
E
Site 16
T267
Q
Q
Y
L
D
D
N
T
V
E
A
V
A
F
R
Site 17
S276
E
A
V
A
F
R
K
S
A
K
E
L
L
Q
L
Site 18
S352
K
F
G
K
V
E
D
S
L
E
L
S
F
Q
G
Site 19
S356
V
E
D
S
L
E
L
S
F
Q
G
K
D
D
V
Site 20
T386
N
G
G
T
Q
A
K
T
G
K
K
F
K
Y
L
Site 21
Y392
K
T
G
K
K
F
K
Y
L
F
P
K
F
T
L
Site 22
Y418
V
P
C
E
T
L
E
Y
I
E
A
N
Y
G
K
Site 23
S439
K
T
W
D
W
K
R
S
P
P
N
V
Q
P
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation