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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0494
Full Name:
EF-hand domain-containing protein KIAA0494
Alias:
K0494; Loc9813
Type:
Uncharacterized protein
Mass (Da):
55031
Number AA:
495
UniProt ID:
O75071
International Prot ID:
IPI00006130
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
L
I
G
L
A
G
D
S
R
R
K
K
P
K
K
Site 2
S27
K
K
P
K
K
G
P
S
S
H
R
L
L
R
T
Site 3
S28
K
P
K
K
G
P
S
S
H
R
L
L
R
T
E
Site 4
T34
S
S
H
R
L
L
R
T
E
P
P
D
S
D
S
Site 5
S39
L
R
T
E
P
P
D
S
D
S
E
S
S
S
E
Site 6
S41
T
E
P
P
D
S
D
S
E
S
S
S
E
E
E
Site 7
S43
P
P
D
S
D
S
E
S
S
S
E
E
E
E
E
Site 8
S45
D
S
D
S
E
S
S
S
E
E
E
E
E
F
G
Site 9
S58
F
G
V
V
G
N
R
S
R
F
A
K
G
D
Y
Site 10
Y65
S
R
F
A
K
G
D
Y
L
R
C
C
K
I
C
Site 11
T111
A
L
K
E
K
F
R
T
M
E
S
N
Q
K
S
Site 12
S114
E
K
F
R
T
M
E
S
N
Q
K
S
S
F
Q
Site 13
S118
T
M
E
S
N
Q
K
S
S
F
Q
E
I
P
K
Site 14
S119
M
E
S
N
Q
K
S
S
F
Q
E
I
P
K
L
Site 15
S132
K
L
N
E
E
L
L
S
K
Q
K
Q
L
E
K
Site 16
S142
K
Q
L
E
K
I
E
S
G
E
M
G
L
N
K
Site 17
S162
T
E
M
N
K
Q
I
S
L
L
T
S
A
V
N
Site 18
T187
D
L
I
S
L
P
T
T
V
E
G
L
Q
K
S
Site 19
S194
T
V
E
G
L
Q
K
S
V
A
S
I
G
N
T
Site 20
T215
A
V
E
A
L
Q
K
T
V
D
E
H
K
K
T
Site 21
T222
T
V
D
E
H
K
K
T
M
E
L
L
Q
S
D
Site 22
T238
N
Q
H
F
L
K
E
T
P
G
S
N
Q
I
I
Site 23
S241
F
L
K
E
T
P
G
S
N
Q
I
I
P
S
P
Site 24
S247
G
S
N
Q
I
I
P
S
P
S
A
T
S
E
L
Site 25
S249
N
Q
I
I
P
S
P
S
A
T
S
E
L
D
N
Site 26
T258
T
S
E
L
D
N
K
T
H
S
E
N
L
K
Q
Site 27
Y269
N
L
K
Q
D
I
L
Y
L
H
N
S
L
E
E
Site 28
S273
D
I
L
Y
L
H
N
S
L
E
E
V
N
S
A
Site 29
S279
N
S
L
E
E
V
N
S
A
L
V
G
Y
Q
R
Site 30
Y284
V
N
S
A
L
V
G
Y
Q
R
Q
N
D
L
K
Site 31
T298
K
L
E
G
M
N
E
T
V
S
N
L
T
Q
R
Site 32
T303
N
E
T
V
S
N
L
T
Q
R
V
N
L
I
E
Site 33
S326
V
E
K
K
A
N
L
S
F
S
M
M
G
D
R
Site 34
S328
K
K
A
N
L
S
F
S
M
M
G
D
R
S
A
Site 35
S334
F
S
M
M
G
D
R
S
A
T
L
K
R
Q
S
Site 36
T336
M
M
G
D
R
S
A
T
L
K
R
Q
S
L
D
Site 37
S341
S
A
T
L
K
R
Q
S
L
D
Q
V
T
N
R
Site 38
T346
R
Q
S
L
D
Q
V
T
N
R
T
D
T
V
K
Site 39
T351
Q
V
T
N
R
T
D
T
V
K
I
Q
S
I
K
Site 40
S362
Q
S
I
K
K
E
D
S
S
N
S
Q
V
S
K
Site 41
S363
S
I
K
K
E
D
S
S
N
S
Q
V
S
K
L
Site 42
S365
K
K
E
D
S
S
N
S
Q
V
S
K
L
R
E
Site 43
S368
D
S
S
N
S
Q
V
S
K
L
R
E
K
L
Q
Site 44
T381
L
Q
L
I
S
A
L
T
N
K
P
E
S
N
R
Site 45
S386
A
L
T
N
K
P
E
S
N
R
P
P
E
T
A
Site 46
S400
A
D
E
E
Q
V
E
S
F
T
S
K
P
S
A
Site 47
S403
E
Q
V
E
S
F
T
S
K
P
S
A
L
P
K
Site 48
S406
E
S
F
T
S
K
P
S
A
L
P
K
F
S
Q
Site 49
S412
P
S
A
L
P
K
F
S
Q
F
L
G
D
P
V
Site 50
S435
I
S
L
P
G
V
S
S
T
E
D
L
Q
D
L
Site 51
T446
L
Q
D
L
F
R
K
T
G
Q
D
V
D
G
K
Site 52
Y456
D
V
D
G
K
L
T
Y
Q
E
I
W
T
S
L
Site 53
S462
T
Y
Q
E
I
W
T
S
L
G
S
A
M
P
E
Site 54
S472
S
A
M
P
E
P
E
S
L
R
A
F
D
S
D
Site 55
S478
E
S
L
R
A
F
D
S
D
G
D
G
R
Y
S
Site 56
Y484
D
S
D
G
D
G
R
Y
S
F
L
E
L
R
V
Site 57
S485
S
D
G
D
G
R
Y
S
F
L
E
L
R
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation