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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOS1AP
Full Name:
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Alias:
CAPON; C-terminal PDZ domain ligand of neuronal nitric oxide synthase; KIAA0464; Nitric oxide synthase 1 (neuronal) adaptor protein
Type:
Adaptor/scaffold
Mass (Da):
56150
Number AA:
506
UniProt ID:
O75052
International Prot ID:
IPI00514825
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0030165
GO:0050998
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
P
S
K
T
K
Y
N
L
V
D
D
G
H
Site 2
S47
L
D
V
P
R
P
N
S
R
V
E
I
V
A
A
Site 3
Y60
A
A
M
R
R
I
R
Y
E
F
K
A
K
N
I
Site 4
S73
N
I
K
K
K
K
V
S
I
M
V
S
V
D
G
Site 5
Y114
L
V
M
Q
D
P
I
Y
R
I
F
Y
V
S
H
Site 6
Y118
D
P
I
Y
R
I
F
Y
V
S
H
D
S
Q
D
Site 7
S123
I
F
Y
V
S
H
D
S
Q
D
L
K
I
F
S
Site 8
Y131
Q
D
L
K
I
F
S
Y
I
A
R
D
G
A
S
Site 9
S152
V
F
K
S
K
K
K
S
Q
A
M
R
I
V
R
Site 10
T176
H
K
L
S
L
Q
H
T
Q
Q
N
A
D
G
Q
Site 11
S188
D
G
Q
E
D
G
E
S
E
R
N
S
N
S
S
Site 12
S192
D
G
E
S
E
R
N
S
N
S
S
G
D
P
G
Site 13
S194
E
S
E
R
N
S
N
S
S
G
D
P
G
R
Q
Site 14
S195
S
E
R
N
S
N
S
S
G
D
P
G
R
Q
L
Site 15
T203
G
D
P
G
R
Q
L
T
G
A
E
R
A
S
T
Site 16
S209
L
T
G
A
E
R
A
S
T
A
T
A
E
E
T
Site 17
T210
T
G
A
E
R
A
S
T
A
T
A
E
E
T
D
Site 18
T238
L
E
F
S
R
G
V
T
D
L
D
A
V
G
K
Site 19
S249
A
V
G
K
E
G
G
S
H
T
G
S
K
V
S
Site 20
T251
G
K
E
G
G
S
H
T
G
S
K
V
S
H
P
Site 21
S253
E
G
G
S
H
T
G
S
K
V
S
H
P
Q
E
Site 22
S256
S
H
T
G
S
K
V
S
H
P
Q
E
P
M
L
Site 23
T264
H
P
Q
E
P
M
L
T
A
S
P
R
M
L
L
Site 24
S266
Q
E
P
M
L
T
A
S
P
R
M
L
L
P
S
Site 25
S273
S
P
R
M
L
L
P
S
S
S
S
K
P
P
G
Site 26
S274
P
R
M
L
L
P
S
S
S
S
K
P
P
G
L
Site 27
S275
R
M
L
L
P
S
S
S
S
K
P
P
G
L
G
Site 28
S276
M
L
L
P
S
S
S
S
K
P
P
G
L
G
T
Site 29
T283
S
K
P
P
G
L
G
T
E
T
P
L
S
T
H
Site 30
T285
P
P
G
L
G
T
E
T
P
L
S
T
H
H
Q
Site 31
S288
L
G
T
E
T
P
L
S
T
H
H
Q
M
Q
L
Site 32
S350
K
D
M
L
Q
H
I
S
L
L
V
K
Q
V
Q
Site 33
S364
Q
E
L
E
L
K
L
S
G
Q
N
A
M
G
S
Site 34
S371
S
G
Q
N
A
M
G
S
Q
D
S
L
L
E
I
Site 35
S374
N
A
M
G
S
Q
D
S
L
L
E
I
T
F
R
Site 36
T379
Q
D
S
L
L
E
I
T
F
R
S
G
A
L
P
Site 37
T393
P
V
L
C
D
P
T
T
P
K
P
E
D
L
H
Site 38
S401
P
K
P
E
D
L
H
S
P
P
L
G
A
G
L
Site 39
S417
D
F
A
H
P
A
G
S
P
L
G
R
R
D
C
Site 40
T439
R
F
L
P
P
E
D
T
P
P
P
A
Q
G
E
Site 41
S460
E
L
I
K
F
R
E
S
G
I
A
S
E
Y
E
Site 42
S464
F
R
E
S
G
I
A
S
E
Y
E
S
N
T
D
Site 43
Y466
E
S
G
I
A
S
E
Y
E
S
N
T
D
E
S
Site 44
S468
G
I
A
S
E
Y
E
S
N
T
D
E
S
E
E
Site 45
S473
Y
E
S
N
T
D
E
S
E
E
R
D
S
W
S
Site 46
S478
D
E
S
E
E
R
D
S
W
S
Q
E
E
L
P
Site 47
S480
S
E
E
R
D
S
W
S
Q
E
E
L
P
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation