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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DTNB
Full Name:
Dystrobrevin beta
Alias:
Beta-dystrobrevin; DTN-B; Dystrobrevin, beta; MGC17163; MGC57126
Type:
Mass (Da):
71360
Number AA:
UniProt ID:
O60941
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
E
S
G
N
K
R
K
T
M
A
E
K
R
Q
L
Site 2
T73
G
L
N
T
L
D
H
T
T
E
I
S
V
S
R
Site 3
T74
L
N
T
L
D
H
T
T
E
I
S
V
S
R
L
Site 4
S77
L
D
H
T
T
E
I
S
V
S
R
L
E
T
V
Site 5
S79
H
T
T
E
I
S
V
S
R
L
E
T
V
I
S
Site 6
S86
S
R
L
E
T
V
I
S
S
I
Y
Y
Q
L
N
Site 7
Y90
T
V
I
S
S
I
Y
Y
Q
L
N
K
R
L
P
Site 8
S98
Q
L
N
K
R
L
P
S
T
H
Q
I
S
V
E
Site 9
T99
L
N
K
R
L
P
S
T
H
Q
I
S
V
E
Q
Site 10
S103
L
P
S
T
H
Q
I
S
V
E
Q
S
I
S
L
Site 11
Y119
L
N
F
M
I
A
A
Y
D
S
E
G
R
G
K
Site 12
S121
F
M
I
A
A
Y
D
S
E
G
R
G
K
L
T
Site 13
T128
S
E
G
R
G
K
L
T
V
F
S
V
K
A
M
Site 14
Y150
K
M
L
D
K
L
R
Y
V
F
S
Q
M
S
D
Site 15
S153
D
K
L
R
Y
V
F
S
Q
M
S
D
S
N
G
Site 16
S156
R
Y
V
F
S
Q
M
S
D
S
N
G
L
M
I
Site 17
S186
T
A
V
F
E
G
P
S
F
G
Y
T
E
H
S
Site 18
T190
E
G
P
S
F
G
Y
T
E
H
S
V
R
T
C
Site 19
S281
G
H
A
G
G
P
H
S
N
Q
H
Q
M
K
E
Site 20
S290
Q
H
Q
M
K
E
H
S
S
W
K
S
P
A
K
Site 21
S294
K
E
H
S
S
W
K
S
P
A
K
K
L
S
H
Site 22
S300
K
S
P
A
K
K
L
S
H
A
I
S
K
S
L
Site 23
S304
K
K
L
S
H
A
I
S
K
S
L
G
C
V
P
Site 24
T312
K
S
L
G
C
V
P
T
R
E
P
P
H
P
V
Site 25
T340
I
V
P
P
R
P
L
T
N
M
N
D
T
M
V
Site 26
T345
P
L
T
N
M
N
D
T
M
V
S
H
M
S
S
Site 27
S352
T
M
V
S
H
M
S
S
G
V
P
T
P
T
K
Site 28
T356
H
M
S
S
G
V
P
T
P
T
K
R
L
Q
Y
Site 29
T358
S
S
G
V
P
T
P
T
K
R
L
Q
Y
S
Q
Site 30
Y363
T
P
T
K
R
L
Q
Y
S
Q
D
I
P
S
H
Site 31
S364
P
T
K
R
L
Q
Y
S
Q
D
I
P
S
H
L
Site 32
S394
H
C
A
R
V
L
D
S
P
S
R
L
D
E
E
Site 33
S396
A
R
V
L
D
S
P
S
R
L
D
E
E
H
R
Site 34
Y408
E
H
R
L
I
A
R
Y
A
A
R
L
A
A
E
Site 35
T420
A
A
E
A
G
N
V
T
R
P
P
T
D
L
S
Site 36
T424
G
N
V
T
R
P
P
T
D
L
S
F
N
F
D
Site 37
S427
T
R
P
P
T
D
L
S
F
N
F
D
A
N
K
Site 38
T468
H
E
Q
A
S
Q
P
T
P
E
K
A
Q
Q
N
Site 39
S497
D
E
L
E
Q
R
M
S
A
L
Q
E
S
R
R
Site 40
S502
R
M
S
A
L
Q
E
S
R
R
E
L
M
V
Q
Site 41
T529
Q
K
Q
A
A
Q
A
T
G
S
P
H
T
S
P
Site 42
S531
Q
A
A
Q
A
T
G
S
P
H
T
S
P
T
H
Site 43
T534
Q
A
T
G
S
P
H
T
S
P
T
H
G
G
G
Site 44
S535
A
T
G
S
P
H
T
S
P
T
H
G
G
G
R
Site 45
T537
G
S
P
H
T
S
P
T
H
G
G
G
R
P
M
Site 46
S550
P
M
P
M
P
V
R
S
T
S
A
G
S
T
P
Site 47
T551
M
P
M
P
V
R
S
T
S
A
G
S
T
P
T
Site 48
S552
P
M
P
V
R
S
T
S
A
G
S
T
P
T
H
Site 49
T556
R
S
T
S
A
G
S
T
P
T
H
C
P
Q
D
Site 50
T558
T
S
A
G
S
T
P
T
H
C
P
Q
D
S
L
Site 51
S564
P
T
H
C
P
Q
D
S
L
S
G
V
G
G
D
Site 52
S566
H
C
P
Q
D
S
L
S
G
V
G
G
D
V
Q
Site 53
T598
A
A
D
S
I
T
N
T
M
S
S
L
V
K
E
Site 54
S601
S
I
T
N
T
M
S
S
L
V
K
E
L
H
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation