PhosphoNET

           
Protein Info 
   
Short Name:  SH2D1A
Full Name:  SH2 domain-containing protein 1A
Alias:  DSHP; Duncan's disease SH2-protein; SH1A; SH21A; signalling lymphocyte activation molecule- associated protein; SLAM-associated protein; T cell signal transduction molecule SAP
Type:  Uncharacterized protein
Mass (Da):  14187
Number AA:  128
UniProt ID:  O60880
International Prot ID:  IPI00032401
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0005070     PhosphoSite+ KinaseNET
Biological Process:  GO:0007267  GO:0006968   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T15HGKISRETGEKLLLA
Site 2Y29ATGLDGSYLLRDSES
Site 3S34GSYLLRDSESVPGVY
Site 4Y52VLYHGYIYTYRVSQT
Site 5T53LYHGYIYTYRVSQTE
Site 6T59YTYRVSQTETGSWSA
Site 7T61YRVSQTETGSWSAET
Site 8S63VSQTETGSWSAETAP
Site 9Y76APGVHKRYFRKIKNL
Site 10S85RKIKNLISAFQKPDQ
Site 11Y100GIVIPLQYPVEKKSS
Site 12S106QYPVEKKSSARSTQG
Site 13S107YPVEKKSSARSTQGT
Site 14S110EKKSSARSTQGTTGI
Site 15T111KKSSARSTQGTTGIR
Site 16T114SARSTQGTTGIREDP
Site 17T115ARSTQGTTGIREDPD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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