KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CCDC22
Full Name:
Coiled-coil domain-containing protein 22
Alias:
CCD22; coiled-coil domain containing 22; coiled-coil domain-containing 22; CXorf37; JM1
Type:
Unknown function
Mass (Da):
70760
Number AA:
UniProt ID:
O60826
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
D
R
I
L
I
H
S
L
R
Q
A
G
T
A
Site 2
T25
A
V
P
P
D
V
Q
T
L
R
A
F
T
T
E
Site 3
S70
A
R
F
R
L
A
M
S
L
A
Q
A
C
M
D
Site 4
Y80
Q
A
C
M
D
L
G
Y
P
L
E
L
G
Y
Q
Site 5
Y91
L
G
Y
Q
N
F
L
Y
P
S
E
P
D
L
R
Site 6
T110
F
L
A
E
R
L
P
T
D
A
S
E
D
A
D
Site 7
S113
E
R
L
P
T
D
A
S
E
D
A
D
Q
P
A
Site 8
T149
W
V
P
P
H
L
R
T
P
K
L
Q
H
L
Q
Site 9
S175
R
L
V
V
P
E
L
S
S
R
G
E
P
R
E
Site 10
S186
E
P
R
E
F
Q
A
S
P
L
L
L
P
V
P
Site 11
T218
A
L
Q
L
C
Q
Q
T
G
R
D
R
P
G
D
Site 12
S233
E
D
W
V
H
R
T
S
R
L
P
P
Q
E
D
Site 13
T253
Q
R
L
Q
K
Q
L
T
E
H
L
R
Q
S
W
Site 14
S259
L
T
E
H
L
R
Q
S
W
G
L
L
G
A
P
Site 15
T285
A
W
G
A
G
A
K
T
G
A
P
K
G
S
R
Site 16
T294
A
P
K
G
S
R
F
T
H
S
E
K
F
T
F
Site 17
S296
K
G
S
R
F
T
H
S
E
K
F
T
F
H
L
Site 18
T300
F
T
H
S
E
K
F
T
F
H
L
E
P
Q
A
Site 19
S313
Q
A
Q
A
T
Q
V
S
D
V
P
A
T
S
R
Site 20
T318
Q
V
S
D
V
P
A
T
S
R
R
P
E
Q
V
Site 21
S319
V
S
D
V
P
A
T
S
R
R
P
E
Q
V
T
Site 22
T326
S
R
R
P
E
Q
V
T
W
A
A
Q
E
Q
E
Site 23
S336
A
Q
E
Q
E
L
E
S
L
R
E
Q
L
E
G
Site 24
S361
D
M
K
T
L
G
V
S
F
V
Q
A
E
S
E
Site 25
S367
V
S
F
V
Q
A
E
S
E
C
R
H
S
K
L
Site 26
S372
A
E
S
E
C
R
H
S
K
L
S
T
A
E
R
Site 27
S375
E
C
R
H
S
K
L
S
T
A
E
R
E
Q
A
Site 28
T376
C
R
H
S
K
L
S
T
A
E
R
E
Q
A
L
Site 29
S387
E
Q
A
L
R
L
K
S
R
A
V
E
L
L
P
Site 30
S410
L
Q
L
V
V
E
N
S
A
Q
R
V
I
H
L
Site 31
S446
Q
D
C
R
E
L
E
S
S
R
R
L
A
E
I
Site 32
S447
D
C
R
E
L
E
S
S
R
R
L
A
E
I
Q
Site 33
S459
E
I
Q
E
L
H
Q
S
V
R
A
A
A
E
E
Site 34
Y474
A
R
R
K
E
E
V
Y
K
Q
L
M
S
E
L
Site 35
T483
Q
L
M
S
E
L
E
T
L
P
R
D
V
S
R
Site 36
S489
E
T
L
P
R
D
V
S
R
L
A
Y
T
Q
R
Site 37
Y493
R
D
V
S
R
L
A
Y
T
Q
R
I
L
E
I
Site 38
S516
E
E
I
T
K
I
L
S
D
T
K
E
L
Q
K
Site 39
S527
E
L
Q
K
E
I
N
S
L
S
G
K
L
D
R
Site 40
T535
L
S
G
K
L
D
R
T
F
A
V
T
D
E
L
Site 41
T539
L
D
R
T
F
A
V
T
D
E
L
V
F
K
D
Site 42
Y557
D
D
A
V
R
K
A
Y
K
Y
L
A
A
L
H
Site 43
Y559
A
V
R
K
A
Y
K
Y
L
A
A
L
H
E
N
Site 44
S568
A
A
L
H
E
N
C
S
Q
L
I
Q
T
I
E
Site 45
T579
Q
T
I
E
D
T
G
T
I
M
R
E
V
R
D
Site 46
T593
D
L
E
E
Q
I
E
T
E
L
G
K
K
T
L
Site 47
T599
E
T
E
L
G
K
K
T
L
S
N
L
E
K
I
Site 48
S601
E
L
G
K
K
T
L
S
N
L
E
K
I
R
E
Site 49
Y610
L
E
K
I
R
E
D
Y
R
A
L
R
Q
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation