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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KPNA6
Full Name:
Importin subunit alpha-7
Alias:
IMA7; Importin alpha-7; IPOA7; Karyopherin alpha-6; Karyopherin subunit alpha-6; KPNA7
Type:
Nuclear pore, Cytoplasm, Nucleus protein
Mass (Da):
60030
Number AA:
536
UniProt ID:
O60684
International Prot ID:
IPI00747764
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005643
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005215
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006605
GO:0006606
GO:0006607
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
E
T
M
A
S
P
G
K
D
Site 2
S6
_
_
M
E
T
M
A
S
P
G
K
D
N
Y
R
Site 3
Y12
A
S
P
G
K
D
N
Y
R
M
K
S
Y
K
N
Site 4
S16
K
D
N
Y
R
M
K
S
Y
K
N
N
A
L
N
Site 5
Y17
D
N
Y
R
M
K
S
Y
K
N
N
A
L
N
P
Site 6
S65
E
E
A
A
M
F
D
S
L
L
M
D
S
Y
V
Site 7
S70
F
D
S
L
L
M
D
S
Y
V
S
S
T
T
G
Site 8
Y71
D
S
L
L
M
D
S
Y
V
S
S
T
T
G
E
Site 9
S91
E
M
V
E
M
L
F
S
D
D
S
D
L
Q
L
Site 10
S94
E
M
L
F
S
D
D
S
D
L
Q
L
A
T
T
Site 11
S109
Q
K
F
R
K
L
L
S
K
E
P
S
P
P
I
Site 12
S113
K
L
L
S
K
E
P
S
P
P
I
D
E
V
I
Site 13
T122
P
I
D
E
V
I
N
T
P
R
V
V
D
R
F
Site 14
S178
I
F
I
E
L
L
N
S
D
F
E
D
V
Q
E
Site 15
T225
L
T
K
S
T
R
L
T
M
T
R
N
A
V
W
Site 16
S277
A
D
A
C
W
A
L
S
Y
L
S
D
G
P
N
Site 17
Y278
D
A
C
W
A
L
S
Y
L
S
D
G
P
N
E
Site 18
S280
C
W
A
L
S
Y
L
S
D
G
P
N
E
K
I
Site 19
Y308
E
L
L
M
H
N
D
Y
K
V
A
S
P
A
L
Site 20
S312
H
N
D
Y
K
V
A
S
P
A
L
R
A
V
G
Site 21
S346
P
C
L
L
H
L
L
S
S
P
K
E
S
I
R
Site 22
S347
C
L
L
H
L
L
S
S
P
K
E
S
I
R
K
Site 23
S351
L
L
S
S
P
K
E
S
I
R
K
E
A
C
W
Site 24
T359
I
R
K
E
A
C
W
T
I
S
N
I
T
A
G
Site 25
T410
T
N
A
T
S
G
G
T
P
E
Q
I
R
Y
L
Site 26
S435
D
L
L
T
V
M
D
S
K
I
V
Q
V
A
L
Site 27
S459
G
E
Q
E
G
K
R
S
G
S
G
V
N
P
Y
Site 28
S461
Q
E
G
K
R
S
G
S
G
V
N
P
Y
C
G
Site 29
Y466
S
G
S
G
V
N
P
Y
C
G
L
I
E
E
A
Site 30
Y474
C
G
L
I
E
E
A
Y
G
L
D
K
I
E
F
Site 31
Y491
S
H
E
N
Q
E
I
Y
Q
K
A
F
D
L
I
Site 32
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
D
Site 33
S509
F
G
V
E
D
D
D
S
S
L
A
P
Q
V
D
Site 34
S510
G
V
E
D
D
D
S
S
L
A
P
Q
V
D
E
Site 35
T518
L
A
P
Q
V
D
E
T
Q
Q
Q
F
I
F
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation