KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KBTBD10
Full Name:
Kelch repeat and BTB domain-containing protein 10
Alias:
KBTBA; Kelch repeat and BTB (POZ) domain containing 10; Kelch-related protein 1; Kel-like protein 23; KRP1; Sarcomeric muscle protein; Sarcosin
Type:
Cytoskeletal protein
Mass (Da):
68040
Number AA:
UniProt ID:
O60662
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005925
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0006941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
L
A
E
E
L
R
L
Y
Q
S
T
L
L
Q
D
Site 2
T17
E
L
R
L
Y
Q
S
T
L
L
Q
D
G
L
K
Site 3
T36
E
K
K
F
I
D
C
T
L
K
A
G
D
K
S
Site 4
S43
T
L
K
A
G
D
K
S
L
P
C
H
R
L
I
Site 5
Y57
I
L
S
A
C
S
P
Y
F
R
E
Y
F
L
S
Site 6
Y61
C
S
P
Y
F
R
E
Y
F
L
S
E
I
D
E
Site 7
S64
Y
F
R
E
Y
F
L
S
E
I
D
E
A
K
K
Site 8
S153
D
C
P
R
L
A
I
S
A
R
E
F
V
S
D
Site 9
S175
E
E
D
F
M
Q
L
S
P
Q
E
L
I
S
V
Site 10
S184
Q
E
L
I
S
V
I
S
N
D
S
L
N
V
E
Site 11
S187
I
S
V
I
S
N
D
S
L
N
V
E
K
E
E
Site 12
S216
E
N
R
V
K
N
L
S
E
V
F
D
C
I
R
Site 13
Y231
F
R
L
M
T
E
K
Y
F
K
D
H
V
E
K
Site 14
S244
E
K
D
D
I
I
K
S
N
P
D
L
Q
K
K
Site 15
S267
A
G
K
L
P
E
P
S
K
N
A
A
K
T
G
Site 16
T273
P
S
K
N
A
A
K
T
G
A
G
E
V
N
G
Site 17
Y291
D
E
D
L
L
P
G
Y
L
N
D
I
P
R
H
Site 18
Y325
D
P
T
E
N
E
C
Y
L
T
A
L
A
E
Q
Site 19
T327
T
E
N
E
C
Y
L
T
A
L
A
E
Q
I
P
Site 20
S338
E
Q
I
P
R
N
H
S
S
I
V
T
Q
Q
N
Site 21
T342
R
N
H
S
S
I
V
T
Q
Q
N
Q
I
Y
V
Site 22
Y354
I
Y
V
V
G
G
L
Y
V
D
E
E
N
K
D
Site 23
S366
N
K
D
Q
P
L
Q
S
Y
F
F
Q
L
D
S
Site 24
Y367
K
D
Q
P
L
Q
S
Y
F
F
Q
L
D
S
I
Site 25
Y401
G
E
V
D
D
K
I
Y
V
V
A
G
K
D
L
Site 26
T410
V
A
G
K
D
L
Q
T
E
A
S
L
D
S
V
Site 27
S413
K
D
L
Q
T
E
A
S
L
D
S
V
L
C
Y
Site 28
Y438
K
K
L
P
I
K
V
Y
G
H
N
V
I
S
H
Site 29
Y450
I
S
H
K
G
M
I
Y
C
L
G
G
K
T
D
Site 30
S509
G
V
T
E
D
G
L
S
A
S
V
E
A
F
D
Site 31
S511
T
E
D
G
L
S
A
S
V
E
A
F
D
L
T
Site 32
T518
S
V
E
A
F
D
L
T
T
N
K
W
D
V
M
Site 33
T526
T
N
K
W
D
V
M
T
E
F
P
Q
E
R
S
Site 34
S534
E
F
P
Q
E
R
S
S
I
S
L
V
S
L
A
Site 35
S536
P
Q
E
R
S
S
I
S
L
V
S
L
A
G
S
Site 36
T563
E
S
K
E
F
A
P
T
E
V
N
D
I
W
K
Site 37
Y571
E
V
N
D
I
W
K
Y
E
D
D
K
K
E
W
Site 38
Y587
G
M
L
K
E
I
R
Y
A
S
G
A
S
C
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation