PhosphoNET

           
Protein Info 
   
Short Name:  ACSL4
Full Name:  Long-chain-fatty-acid--CoA ligase 4
Alias:  ACS4, FACL4, LACS4; Long-chain acyl-CoA synthetase 4
Type:  Peroxisomal membrane, Cytoplasm, Mitochondrial outer membrane, Plasma membrane, Endoplasmic reticulum, Mitochondrion, Peroxisome, Microsome, Endoplasmic reticulum membrane, Integral membrane protein
Mass (Da):  79188
Number AA:  711
UniProt ID:  O60488
International Prot ID:  IPI00029737
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000267  GO:0005624  GO:0005626 Uniprot OncoNet
Molecular Function:  GO:0000287  GO:0003824  GO:0004467 PhosphoSite+ KinaseNET
Biological Process:  GO:0006082  GO:0006629  GO:0006631 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S23HLLITIYSALIFIPW
Site 2Y31ALIFIPWYFLTNAKK
Site 3T34FIPWYFLTNAKKKNA
Site 4S52RIKAKPTSDKPGSPY
Site 5S57PTSDKPGSPYRSVTH
Site 6Y59SDKPGSPYRSVTHFD
Site 7S61KPGSPYRSVTHFDSL
Site 8T63GSPYRSVTHFDSLAV
Site 9T78IDIPGADTLDKLFDH
Site 10S88KLFDHAVSKFGKKDS
Site 11S95SKFGKKDSLGTREIL
Site 12Y123KKLILGNYKWMNYLE
Site 13Y128GNYKWMNYLEVNRRV
Site 14S140RRVNNFGSGLTALGL
Site 15S199GLNESEASYLITSVE
Site 16Y227SCVKHIIYVDNKAIN
Site 17Y238KAINKAEYPEGFEIH
Site 18S249FEIHSMQSVEELGSN
Site 19S255QSVEELGSNPENLGI
Site 20S265ENLGIPPSRPTPSDM
Site 21T268GIPPSRPTPSDMAIV
Site 22S270PPSRPTPSDMAIVMY
Site 23Y277SDMAIVMYTSGSTGR
Site 24S281IVMYTSGSTGRPKGV
Site 25T282VMYTSGSTGRPKGVM
Site 26T314PGLGPKDTYIGYLPL
Site 27Y342TYGCRIGYSSPLTLS
Site 28S343YGCRIGYSSPLTLSD
Site 29S344GCRIGYSSPLTLSDQ
Site 30T347IGYSSPLTLSDQSSK
Site 31S349YSSPLTLSDQSSKIK
Site 32S353LTLSDQSSKIKKGSK
Site 33T364KGSKGDCTVLKPTLM
Site 34Y382PEIMDRIYKNVMSKV
Site 35Y394SKVQEMNYIQKTLFK
Site 36Y404KTLFKIGYDYKLEQI
Site 37Y406LFKIGYDYKLEQIKK
Site 38Y415LEQIKKGYDAPLCNL
Site 39S447LSGGAPLSPQTHRFM
Site 40T450GAPLSPQTHRFMNVC
Site 41T469IGQGYGLTESCGAGT
Site 42S471QGYGLTESCGAGTVT
Site 43Y483TVTEVTDYTTGRVGA
Site 44T484VTEVTDYTTGRVGAP
Site 45T485TEVTDYTTGRVGAPL
Site 46T508DWQEGGYTVHDKPNP
Site 47Y530GQNISMGYFKNEEKT
Site 48Y541EEKTAEDYSVDENGQ
Site 49S542EKTAEDYSVDENGQR
Site 50Y582VKLQAGEYVSLGKVE
Site 51S584LQAGEYVSLGKVEAA
Site 52S614SDQSYVISFVVPNQK
Site 53T624VPNQKRLTLLAQQKG
Site 54S674IPIKVRLSPEPWTPE
Site 55T679RLSPEPWTPETGLVT
Site 56T682PEPWTPETGLVTDAF
Site 57Y700RKELRNHYLKDIERM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation