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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EVI5
Full Name:
Ecotropic viral integration site 5 protein homolog
Alias:
ecotropic viral integration site 5; NB4S; neuroblastoma stage 4S gene protein
Type:
Mass (Da):
92935
Number AA:
810
UniProt ID:
O60447
International Prot ID:
IPI00029661
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005634
GO:0005819
Uniprot
OncoNet
Molecular Function:
GO:0005097
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0051301
GO:0008283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
T
A
A
F
R
N
P
S
G
K
Q
V
A
T
D
Site 2
S28
D
K
V
A
E
K
L
S
S
T
L
S
W
V
K
Site 3
S29
K
V
A
E
K
L
S
S
T
L
S
W
V
K
N
Site 4
S32
E
K
L
S
S
T
L
S
W
V
K
N
T
V
S
Site 5
T37
T
L
S
W
V
K
N
T
V
S
H
T
V
S
Q
Site 6
S43
N
T
V
S
H
T
V
S
Q
M
A
S
Q
V
A
Site 7
S47
H
T
V
S
Q
M
A
S
Q
V
A
S
P
S
T
Site 8
S51
Q
M
A
S
Q
V
A
S
P
S
T
S
L
H
T
Site 9
S53
A
S
Q
V
A
S
P
S
T
S
L
H
T
T
S
Site 10
S55
Q
V
A
S
P
S
T
S
L
H
T
T
S
S
S
Site 11
T58
S
P
S
T
S
L
H
T
T
S
S
S
T
T
L
Site 12
T59
P
S
T
S
L
H
T
T
S
S
S
T
T
L
S
Site 13
S60
S
T
S
L
H
T
T
S
S
S
T
T
L
S
T
Site 14
S61
T
S
L
H
T
T
S
S
S
T
T
L
S
T
P
Site 15
S62
S
L
H
T
T
S
S
S
T
T
L
S
T
P
A
Site 16
T64
H
T
T
S
S
S
T
T
L
S
T
P
A
L
S
Site 17
S66
T
S
S
S
T
T
L
S
T
P
A
L
S
P
S
Site 18
T67
S
S
S
T
T
L
S
T
P
A
L
S
P
S
S
Site 19
S71
T
L
S
T
P
A
L
S
P
S
S
P
S
Q
L
Site 20
S73
S
T
P
A
L
S
P
S
S
P
S
Q
L
S
P
Site 21
S74
T
P
A
L
S
P
S
S
P
S
Q
L
S
P
D
Site 22
S79
P
S
S
P
S
Q
L
S
P
D
D
L
E
L
L
Site 23
T98
E
Q
N
R
L
L
E
T
D
S
K
S
L
R
S
Site 24
S100
N
R
L
L
E
T
D
S
K
S
L
R
S
V
N
Site 25
S102
L
L
E
T
D
S
K
S
L
R
S
V
N
G
S
Site 26
S105
T
D
S
K
S
L
R
S
V
N
G
S
R
R
N
Site 27
S109
S
L
R
S
V
N
G
S
R
R
N
S
G
S
S
Site 28
S113
V
N
G
S
R
R
N
S
G
S
S
L
V
S
S
Site 29
S115
G
S
R
R
N
S
G
S
S
L
V
S
S
S
S
Site 30
S116
S
R
R
N
S
G
S
S
L
V
S
S
S
S
A
Site 31
S119
N
S
G
S
S
L
V
S
S
S
S
A
S
S
N
Site 32
S120
S
G
S
S
L
V
S
S
S
S
A
S
S
N
L
Site 33
S121
G
S
S
L
V
S
S
S
S
A
S
S
N
L
S
Site 34
S122
S
S
L
V
S
S
S
S
A
S
S
N
L
S
H
Site 35
S124
L
V
S
S
S
S
A
S
S
N
L
S
H
L
E
Site 36
S125
V
S
S
S
S
A
S
S
N
L
S
H
L
E
E
Site 37
S128
S
S
A
S
S
N
L
S
H
L
E
E
D
S
W
Site 38
S181
Q
L
L
C
S
A
Q
S
M
P
I
K
D
Q
Y
Site 39
Y188
S
M
P
I
K
D
Q
Y
S
E
L
L
K
M
T
Site 40
S189
M
P
I
K
D
Q
Y
S
E
L
L
K
M
T
S
Site 41
S196
S
E
L
L
K
M
T
S
P
C
E
K
L
I
R
Site 42
T209
I
R
R
D
I
A
R
T
Y
P
E
H
N
F
F
Site 43
Y210
R
R
D
I
A
R
T
Y
P
E
H
N
F
F
K
Site 44
Y274
F
V
K
L
M
Q
D
Y
R
L
R
E
L
F
K
Site 45
Y319
Q
S
F
H
T
S
M
Y
A
S
S
W
F
L
T
Site 46
Y399
D
K
L
I
Q
A
A
Y
Q
V
K
Y
N
S
K
Site 47
Y403
Q
A
A
Y
Q
V
K
Y
N
S
K
K
M
K
K
Site 48
T416
K
K
L
E
K
E
Y
T
T
I
K
T
K
E
M
Site 49
T434
V
E
I
K
R
L
R
T
E
N
R
L
L
K
Q
Site 50
T445
L
L
K
Q
R
I
E
T
L
E
K
H
K
C
S
Site 51
Y455
K
H
K
C
S
S
N
Y
N
E
D
F
V
L
Q
Site 52
S473
E
L
V
Q
A
R
L
S
E
A
E
S
Q
C
A
Site 53
S477
A
R
L
S
E
A
E
S
Q
C
A
L
K
E
M
Site 54
S497
D
I
E
K
R
N
N
S
L
P
D
E
N
N
I
Site 55
T546
W
Q
R
H
L
A
R
T
T
G
R
W
K
D
P
Site 56
T547
Q
R
H
L
A
R
T
T
G
R
W
K
D
P
P
Site 57
Y617
S
L
Q
E
K
V
Q
Y
L
S
A
Q
N
K
G
Site 58
S630
K
G
L
L
T
Q
L
S
E
A
K
R
K
Q
A
Site 59
S687
L
Q
G
Q
L
N
K
S
D
S
N
Q
Y
I
G
Site 60
S689
G
Q
L
N
K
S
D
S
N
Q
Y
I
G
E
L
Site 61
S717
L
K
G
Q
R
G
F
S
G
Q
P
P
F
D
G
Site 62
S737
H
L
I
G
D
D
E
S
F
H
S
S
D
E
D
Site 63
S740
G
D
D
E
S
F
H
S
S
D
E
D
F
I
D
Site 64
S741
D
D
E
S
F
H
S
S
D
E
D
F
I
D
N
Site 65
S749
D
E
D
F
I
D
N
S
L
Q
E
T
G
V
G
Site 66
T753
I
D
N
S
L
Q
E
T
G
V
G
F
P
L
H
Site 67
S763
G
F
P
L
H
G
K
S
G
S
M
S
L
D
P
Site 68
S765
P
L
H
G
K
S
G
S
M
S
L
D
P
A
V
Site 69
S767
H
G
K
S
G
S
M
S
L
D
P
A
V
A
D
Site 70
S776
D
P
A
V
A
D
G
S
E
S
E
T
E
D
S
Site 71
S778
A
V
A
D
G
S
E
S
E
T
E
D
S
V
L
Site 72
T780
A
D
G
S
E
S
E
T
E
D
S
V
L
E
T
Site 73
S783
S
E
S
E
T
E
D
S
V
L
E
T
R
E
S
Site 74
S790
S
V
L
E
T
R
E
S
N
Q
V
V
Q
K
E
Site 75
S805
R
P
P
R
R
R
E
S
Y
S
T
T
V
_
_
Site 76
Y806
P
P
R
R
R
E
S
Y
S
T
T
V
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation