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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HBP1
Full Name:
HMG box-containing protein 1
Alias:
HMG box transcription factor 1;High mobility group box transcription factor 1
Type:
Nucleus protein
Mass (Da):
57645
Number AA:
514
UniProt ID:
O60381
International Prot ID:
IPI00099615
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0007050
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
L
V
M
D
K
R
A
S
G
M
N
D
S
L
E
Site 2
S31
R
A
S
G
M
N
D
S
L
E
L
L
Q
C
N
Site 3
S43
Q
C
N
E
N
L
P
S
S
P
G
Y
N
S
C
Site 4
S44
C
N
E
N
L
P
S
S
P
G
Y
N
S
C
D
Site 5
Y47
N
L
P
S
S
P
G
Y
N
S
C
D
E
H
M
Site 6
S49
P
S
S
P
G
Y
N
S
C
D
E
H
M
E
L
Site 7
S67
P
E
L
Q
A
V
Q
S
D
P
T
Q
S
G
M
Site 8
T70
Q
A
V
Q
S
D
P
T
Q
S
G
M
Y
Q
L
Site 9
S72
V
Q
S
D
P
T
Q
S
G
M
Y
Q
L
S
S
Site 10
S78
Q
S
G
M
Y
Q
L
S
S
D
V
S
H
Q
E
Site 11
S79
S
G
M
Y
Q
L
S
S
D
V
S
H
Q
E
Y
Site 12
S82
Y
Q
L
S
S
D
V
S
H
Q
E
Y
P
R
S
Site 13
Y86
S
D
V
S
H
Q
E
Y
P
R
S
S
W
N
Q
Site 14
S89
S
H
Q
E
Y
P
R
S
S
W
N
Q
N
T
S
Site 15
S90
H
Q
E
Y
P
R
S
S
W
N
Q
N
T
S
D
Site 16
S96
S
S
W
N
Q
N
T
S
D
I
P
E
T
T
Y
Site 17
Y103
S
D
I
P
E
T
T
Y
R
E
N
E
V
D
W
Site 18
T112
E
N
E
V
D
W
L
T
E
L
A
N
I
A
T
Site 19
T119
T
E
L
A
N
I
A
T
S
P
Q
S
P
L
M
Site 20
S120
E
L
A
N
I
A
T
S
P
Q
S
P
L
M
Q
Site 21
S123
N
I
A
T
S
P
Q
S
P
L
M
Q
C
S
F
Site 22
S129
Q
S
P
L
M
Q
C
S
F
Y
N
R
S
S
P
Site 23
Y131
P
L
M
Q
C
S
F
Y
N
R
S
S
P
V
H
Site 24
S145
H
I
I
A
T
S
K
S
L
H
S
Y
A
R
P
Site 25
S148
A
T
S
K
S
L
H
S
Y
A
R
P
P
P
V
Site 26
Y149
T
S
K
S
L
H
S
Y
A
R
P
P
P
V
S
Site 27
S156
Y
A
R
P
P
P
V
S
S
S
S
K
S
E
P
Site 28
S157
A
R
P
P
P
V
S
S
S
S
K
S
E
P
A
Site 29
S158
R
P
P
P
V
S
S
S
S
K
S
E
P
A
F
Site 30
S159
P
P
P
V
S
S
S
S
K
S
E
P
A
F
P
Site 31
S161
P
V
S
S
S
S
K
S
E
P
A
F
P
H
H
Site 32
T174
H
H
H
W
K
E
E
T
P
V
R
H
E
R
A
Site 33
S183
V
R
H
E
R
A
N
S
E
S
E
S
G
I
F
Site 34
S185
H
E
R
A
N
S
E
S
E
S
G
I
F
C
M
Site 35
S187
R
A
N
S
E
S
E
S
G
I
F
C
M
S
S
Site 36
S193
E
S
G
I
F
C
M
S
S
L
S
D
D
D
D
Site 37
S194
S
G
I
F
C
M
S
S
L
S
D
D
D
D
L
Site 38
S196
I
F
C
M
S
S
L
S
D
D
D
D
L
G
W
Site 39
Y257
Q
M
G
I
H
K
G
Y
G
S
D
G
L
K
L
Site 40
S259
G
I
H
K
G
Y
G
S
D
G
L
K
L
L
S
Site 41
S266
S
D
G
L
K
L
L
S
H
E
E
S
V
S
F
Site 42
S270
K
L
L
S
H
E
E
S
V
S
F
G
E
S
V
Site 43
S272
L
S
H
E
E
S
V
S
F
G
E
S
V
L
K
Site 44
T281
G
E
S
V
L
K
L
T
F
D
P
G
T
V
E
Site 45
T286
K
L
T
F
D
P
G
T
V
E
D
G
L
L
T
Site 46
T293
T
V
E
D
G
L
L
T
V
E
C
K
L
D
H
Site 47
Y303
C
K
L
D
H
P
F
Y
V
K
N
K
G
W
S
Site 48
S311
V
K
N
K
G
W
S
S
F
Y
P
S
L
T
V
Site 49
Y313
N
K
G
W
S
S
F
Y
P
S
L
T
V
V
Q
Site 50
S315
G
W
S
S
F
Y
P
S
L
T
V
V
Q
H
G
Site 51
S348
D
A
I
N
F
D
D
S
G
V
F
D
T
F
K
Site 52
T353
D
D
S
G
V
F
D
T
F
K
S
Y
D
F
T
Site 53
T360
T
F
K
S
Y
D
F
T
P
M
D
S
S
A
V
Site 54
S380
M
A
R
Q
R
R
A
S
L
S
C
G
G
P
G
Site 55
S382
R
Q
R
R
A
S
L
S
C
G
G
P
G
G
Q
Site 56
S394
G
G
Q
D
F
A
R
S
G
F
S
K
N
C
G
Site 57
S397
D
F
A
R
S
G
F
S
K
N
C
G
S
P
G
Site 58
S402
G
F
S
K
N
C
G
S
P
G
S
S
Q
L
S
Site 59
S405
K
N
C
G
S
P
G
S
S
Q
L
S
S
N
S
Site 60
S406
N
C
G
S
P
G
S
S
Q
L
S
S
N
S
L
Site 61
S409
S
P
G
S
S
Q
L
S
S
N
S
L
Y
A
K
Site 62
S410
P
G
S
S
Q
L
S
S
N
S
L
Y
A
K
A
Site 63
S412
S
S
Q
L
S
S
N
S
L
Y
A
K
A
V
K
Site 64
Y414
Q
L
S
S
N
S
L
Y
A
K
A
V
K
N
H
Site 65
S422
A
K
A
V
K
N
H
S
S
G
T
V
S
A
T
Site 66
S423
K
A
V
K
N
H
S
S
G
T
V
S
A
T
S
Site 67
T425
V
K
N
H
S
S
G
T
V
S
A
T
S
P
N
Site 68
S427
N
H
S
S
G
T
V
S
A
T
S
P
N
K
C
Site 69
S430
S
G
T
V
S
A
T
S
P
N
K
C
K
R
P
Site 70
Y448
F
M
L
F
A
K
K
Y
R
V
E
Y
T
Q
M
Site 71
Y452
A
K
K
Y
R
V
E
Y
T
Q
M
Y
P
G
K
Site 72
Y456
R
V
E
Y
T
Q
M
Y
P
G
K
D
N
R
A
Site 73
S465
G
K
D
N
R
A
I
S
V
I
L
G
D
R
W
Site 74
Y483
K
N
E
E
R
R
M
Y
T
L
E
A
K
A
L
Site 75
T484
N
E
E
R
R
M
Y
T
L
E
A
K
A
L
A
Site 76
T507
D
C
W
K
R
K
R
T
N
S
G
S
Q
Q
H
Site 77
S509
W
K
R
K
R
T
N
S
G
S
Q
Q
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation