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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXTL3
Full Name:
Exostosin-like 3
Alias:
EXT-related protein 1;Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;Hereditary multiple exostoses gene isolog;Multiple exostosis-like protein 3;Putative tumor suppressor protein EXTL3
Type:
Mass (Da):
104749
Number AA:
919
UniProt ID:
O43909
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S88
D
L
C
R
I
R
E
S
V
S
E
E
L
L
Q
Site 2
S90
C
R
I
R
E
S
V
S
E
E
L
L
Q
L
E
Site 3
S105
A
K
R
Q
E
L
N
S
E
I
A
K
L
N
L
Site 4
S120
K
I
E
A
C
K
K
S
I
E
N
A
K
Q
D
Site 5
S136
L
Q
L
K
N
V
I
S
Q
T
E
H
S
Y
K
Site 6
S154
A
Q
N
Q
P
K
L
S
L
P
I
R
L
L
P
Site 7
Y185
R
L
H
N
C
F
D
Y
S
R
C
P
L
T
S
Site 8
T191
D
Y
S
R
C
P
L
T
S
G
F
P
V
Y
V
Site 9
Y197
L
T
S
G
F
P
V
Y
V
Y
D
S
D
Q
F
Site 10
Y209
D
Q
F
V
F
G
S
Y
L
D
P
L
V
K
Q
Site 11
Y227
A
T
A
R
A
N
V
Y
V
T
E
N
A
D
I
Site 12
Y261
A
E
L
E
K
Q
L
Y
S
L
P
H
W
R
T
Site 13
S279
N
H
V
I
I
N
L
S
R
K
S
D
T
Q
N
Site 14
S282
I
I
N
L
S
R
K
S
D
T
Q
N
L
L
Y
Site 15
Y289
S
D
T
Q
N
L
L
Y
N
V
S
T
G
R
A
Site 16
T302
R
A
M
V
A
Q
S
T
F
Y
T
V
Q
Y
R
Site 17
T305
V
A
Q
S
T
F
Y
T
V
Q
Y
R
P
G
F
Site 18
Y308
S
T
F
Y
T
V
Q
Y
R
P
G
F
D
L
V
Site 19
Y341
Q
V
P
V
K
R
K
Y
L
F
T
F
Q
G
E
Site 20
T344
V
K
R
K
Y
L
F
T
F
Q
G
E
K
I
E
Site 21
S352
F
Q
G
E
K
I
E
S
L
R
S
S
L
Q
E
Site 22
S355
E
K
I
E
S
L
R
S
S
L
Q
E
A
R
S
Site 23
S356
K
I
E
S
L
R
S
S
L
Q
E
A
R
S
F
Site 24
S362
S
S
L
Q
E
A
R
S
F
E
E
E
M
E
G
Site 25
Y375
E
G
D
P
P
A
D
Y
D
D
R
I
I
A
T
Site 26
S407
C
K
N
Q
P
K
P
S
L
P
T
E
W
A
L
Site 27
S499
E
V
H
F
L
L
R
S
L
S
D
S
D
L
L
Site 28
S501
H
F
L
L
R
S
L
S
D
S
D
L
L
A
M
Site 29
S503
L
L
R
S
L
S
D
S
D
L
L
A
M
R
R
Site 30
T518
Q
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
Site 31
Y519
G
R
F
L
W
E
T
Y
F
S
T
A
D
S
I
Site 32
T580
L
D
L
G
P
V
E
T
E
P
P
Y
A
S
P
Site 33
Y584
P
V
E
T
E
P
P
Y
A
S
P
R
Y
L
R
Site 34
S586
E
T
E
P
P
Y
A
S
P
R
Y
L
R
N
F
Site 35
Y589
P
P
Y
A
S
P
R
Y
L
R
N
F
T
L
T
Site 36
T594
P
R
Y
L
R
N
F
T
L
T
V
T
D
F
Y
Site 37
T596
Y
L
R
N
F
T
L
T
V
T
D
F
Y
R
S
Site 38
Y601
T
L
T
V
T
D
F
Y
R
S
W
N
C
A
P
Site 39
S625
P
F
D
P
V
L
P
S
E
A
K
F
L
G
S
Site 40
S632
S
E
A
K
F
L
G
S
G
T
G
F
R
P
I
Site 41
S646
I
G
G
G
A
G
G
S
G
K
E
F
Q
A
A
Site 42
T664
N
V
P
R
E
Q
F
T
V
V
M
L
T
Y
E
Site 43
S679
R
E
E
V
L
M
N
S
L
E
R
L
N
G
L
Site 44
S698
K
V
V
V
V
W
N
S
P
K
L
P
S
E
D
Site 45
S703
W
N
S
P
K
L
P
S
E
D
L
L
W
P
D
Site 46
S724
V
V
R
T
E
K
N
S
L
N
N
R
F
L
P
Site 47
Y791
S
W
L
Y
N
S
N
Y
S
C
E
L
S
M
V
Site 48
Y808
G
A
A
F
F
H
K
Y
Y
A
Y
L
Y
S
Y
Site 49
Y811
F
F
H
K
Y
Y
A
Y
L
Y
S
Y
V
M
P
Site 50
Y813
H
K
Y
Y
A
Y
L
Y
S
Y
V
M
P
Q
A
Site 51
Y815
Y
Y
A
Y
L
Y
S
Y
V
M
P
Q
A
I
R
Site 52
Y828
I
R
D
M
V
D
E
Y
I
N
C
E
D
I
A
Site 53
S867
P
G
C
P
Q
A
L
S
H
D
D
S
H
F
H
Site 54
S871
Q
A
L
S
H
D
D
S
H
F
H
E
R
H
K
Site 55
Y894
Y
G
Y
M
P
L
L
Y
T
Q
F
R
V
D
S
Site 56
S901
Y
T
Q
F
R
V
D
S
V
L
F
K
T
R
L
Site 57
T906
V
D
S
V
L
F
K
T
R
L
P
H
D
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation