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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIF1C
Full Name:
Kinesin-like protein KIF1C
Alias:
Kinesin family member 1C; LTXS1
Type:
Microtubule binding protein; Motor protein
Mass (Da):
122947
Number AA:
1103
UniProt ID:
O43896
International Prot ID:
IPI00179757
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0006890
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
R
P
F
N
A
R
E
T
S
Q
D
A
K
C
V
Site 2
S21
P
F
N
A
R
E
T
S
Q
D
A
K
C
V
V
Site 3
S29
Q
D
A
K
C
V
V
S
M
Q
G
N
T
T
S
Site 4
S36
S
M
Q
G
N
T
T
S
I
I
N
P
K
Q
S
Site 5
S43
S
I
I
N
P
K
Q
S
K
D
A
P
K
S
F
Site 6
S49
Q
S
K
D
A
P
K
S
F
T
F
D
Y
S
Y
Site 7
T51
K
D
A
P
K
S
F
T
F
D
Y
S
Y
W
S
Site 8
Y54
P
K
S
F
T
F
D
Y
S
Y
W
S
H
T
S
Site 9
Y56
S
F
T
F
D
Y
S
Y
W
S
H
T
S
T
E
Site 10
T62
S
Y
W
S
H
T
S
T
E
D
P
Q
F
A
S
Site 11
S69
T
E
D
P
Q
F
A
S
Q
Q
Q
V
Y
R
D
Site 12
S104
G
Q
T
G
A
G
K
S
Y
T
M
M
G
R
Q
Site 13
T106
T
G
A
G
K
S
Y
T
M
M
G
R
Q
E
P
Site 14
S128
Q
L
C
E
D
L
F
S
R
V
S
E
N
Q
S
Site 15
S131
E
D
L
F
S
R
V
S
E
N
Q
S
A
Q
L
Site 16
S135
S
R
V
S
E
N
Q
S
A
Q
L
S
Y
S
V
Site 17
S139
E
N
Q
S
A
Q
L
S
Y
S
V
E
V
S
Y
Site 18
S141
Q
S
A
Q
L
S
Y
S
V
E
V
S
Y
M
E
Site 19
Y146
S
Y
S
V
E
V
S
Y
M
E
I
Y
C
E
R
Site 20
Y150
E
V
S
Y
M
E
I
Y
C
E
R
V
R
D
L
Site 21
S162
R
D
L
L
N
P
K
S
R
G
S
L
R
V
R
Site 22
S165
L
N
P
K
S
R
G
S
L
R
V
R
E
H
P
Site 23
Y177
E
H
P
I
L
G
P
Y
V
Q
D
L
S
K
L
Site 24
S182
G
P
Y
V
Q
D
L
S
K
L
A
V
T
S
Y
Site 25
T204
D
C
G
N
K
A
R
T
V
A
A
T
N
M
N
Site 26
T208
K
A
R
T
V
A
A
T
N
M
N
E
T
S
S
Site 27
T213
A
A
T
N
M
N
E
T
S
S
R
S
H
A
V
Site 28
S214
A
T
N
M
N
E
T
S
S
R
S
H
A
V
F
Site 29
S217
M
N
E
T
S
S
R
S
H
A
V
F
T
I
V
Site 30
T222
S
R
S
H
A
V
F
T
I
V
F
T
Q
R
C
Site 31
T234
Q
R
C
H
D
Q
L
T
G
L
D
S
E
K
V
Site 32
S238
D
Q
L
T
G
L
D
S
E
K
V
S
K
I
S
Site 33
S252
S
L
V
D
L
A
G
S
E
R
A
D
S
S
G
Site 34
S257
A
G
S
E
R
A
D
S
S
G
A
R
G
M
R
Site 35
S258
G
S
E
R
A
D
S
S
G
A
R
G
M
R
L
Site 36
S274
E
G
A
N
I
N
K
S
L
T
T
L
G
K
V
Site 37
S290
S
A
L
A
D
M
Q
S
K
K
R
K
S
D
F
Site 38
S295
M
Q
S
K
K
R
K
S
D
F
I
P
Y
R
D
Site 39
Y300
R
K
S
D
F
I
P
Y
R
D
S
V
L
T
W
Site 40
T306
P
Y
R
D
S
V
L
T
W
L
L
K
E
N
L
Site 41
Y332
L
S
P
A
D
I
N
Y
E
E
T
L
S
T
L
Site 42
S337
I
N
Y
E
E
T
L
S
T
L
R
Y
A
D
R
Site 43
T338
N
Y
E
E
T
L
S
T
L
R
Y
A
D
R
T
Site 44
Y341
E
T
L
S
T
L
R
Y
A
D
R
T
K
Q
I
Site 45
T345
T
L
R
Y
A
D
R
T
K
Q
I
R
C
N
A
Site 46
T392
S
A
L
E
G
L
K
T
E
E
G
S
V
R
G
Site 47
S396
G
L
K
T
E
E
G
S
V
R
G
A
L
P
A
Site 48
S412
S
S
P
P
A
P
V
S
P
S
S
P
T
T
H
Site 49
S414
P
P
A
P
V
S
P
S
S
P
T
T
H
N
G
Site 50
S415
P
A
P
V
S
P
S
S
P
T
T
H
N
G
E
Site 51
T418
V
S
P
S
S
P
T
T
H
N
G
E
L
E
P
Site 52
S426
H
N
G
E
L
E
P
S
F
S
P
N
T
E
S
Site 53
S428
G
E
L
E
P
S
F
S
P
N
T
E
S
Q
I
Site 54
T431
E
P
S
F
S
P
N
T
E
S
Q
I
G
P
E
Site 55
S433
S
F
S
P
N
T
E
S
Q
I
G
P
E
E
A
Site 56
T457
I
I
A
E
L
N
E
T
W
E
E
K
L
R
K
Site 57
T465
W
E
E
K
L
R
K
T
E
A
L
R
M
E
R
Site 58
T489
A
V
R
E
D
G
G
T
V
G
V
F
S
P
K
Site 59
S494
G
G
T
V
G
V
F
S
P
K
K
T
P
H
L
Site 60
T498
G
V
F
S
P
K
K
T
P
H
L
V
N
L
N
Site 61
T568
E
P
C
E
G
A
E
T
Y
V
N
G
K
L
V
Site 62
Y569
P
C
E
G
A
E
T
Y
V
N
G
K
L
V
T
Site 63
S619
P
P
P
P
G
P
P
S
E
P
V
D
W
N
F
Site 64
Y671
L
L
E
Q
Q
R
L
Y
A
D
S
D
S
G
D
Site 65
S674
Q
Q
R
L
Y
A
D
S
D
S
G
D
D
S
D
Site 66
S676
R
L
Y
A
D
S
D
S
G
D
D
S
D
K
R
Site 67
S680
D
S
D
S
G
D
D
S
D
K
R
S
C
E
E
Site 68
S684
G
D
D
S
D
K
R
S
C
E
E
S
W
R
L
Site 69
S688
D
K
R
S
C
E
E
S
W
R
L
I
S
S
L
Site 70
S693
E
E
S
W
R
L
I
S
S
L
R
E
Q
L
P
Site 71
S694
E
S
W
R
L
I
S
S
L
R
E
Q
L
P
P
Site 72
T702
L
R
E
Q
L
P
P
T
T
V
Q
T
I
V
K
Site 73
T703
R
E
Q
L
P
P
T
T
V
Q
T
I
V
K
R
Site 74
S715
V
K
R
C
G
L
P
S
S
G
K
R
R
A
P
Site 75
S716
K
R
C
G
L
P
S
S
G
K
R
R
A
P
R
Site 76
Y726
R
R
A
P
R
R
V
Y
Q
I
P
Q
R
R
R
Site 77
T743
G
K
D
P
R
W
A
T
M
A
D
L
K
M
Q
Site 78
T785
K
M
R
E
L
C
R
T
Y
G
K
P
D
G
P
Site 79
Y786
M
R
E
L
C
R
T
Y
G
K
P
D
G
P
G
Site 80
T806
V
A
R
D
V
W
D
T
V
G
E
E
E
G
G
Site 81
S817
E
E
G
G
G
A
G
S
G
G
G
S
E
E
G
Site 82
S821
G
A
G
S
G
G
G
S
E
E
G
A
R
G
A
Site 83
T841
R
A
H
I
D
K
L
T
G
I
L
Q
E
V
K
Site 84
S853
E
V
K
L
Q
N
S
S
K
D
R
E
L
Q
A
Site 85
S905
A
A
E
E
A
A
P
S
D
R
M
P
S
A
R
Site 86
S910
A
P
S
D
R
M
P
S
A
R
P
P
S
P
P
Site 87
S915
M
P
S
A
R
P
P
S
P
P
L
S
S
W
E
Site 88
S919
R
P
P
S
P
P
L
S
S
W
E
R
V
S
R
Site 89
S920
P
P
S
P
P
L
S
S
W
E
R
V
S
R
L
Site 90
S925
L
S
S
W
E
R
V
S
R
L
M
E
E
D
P
Site 91
S955
R
L
Q
G
L
Q
G
S
G
G
R
G
G
G
L
Site 92
S983
K
L
R
F
P
F
K
S
N
P
Q
H
R
E
S
Site 93
S990
S
N
P
Q
H
R
E
S
W
P
G
M
G
S
G
Site 94
S996
E
S
W
P
G
M
G
S
G
E
A
P
T
P
L
Site 95
T1001
M
G
S
G
E
A
P
T
P
L
Q
P
P
E
E
Site 96
T1010
L
Q
P
P
E
E
V
T
P
H
P
A
T
P
A
Site 97
T1015
E
V
T
P
H
P
A
T
P
A
R
R
P
P
S
Site 98
S1022
T
P
A
R
R
P
P
S
P
R
R
S
H
H
P
Site 99
S1026
R
P
P
S
P
R
R
S
H
H
P
R
R
N
S
Site 100
S1033
S
H
H
P
R
R
N
S
L
D
G
G
G
R
S
Site 101
S1040
S
L
D
G
G
G
R
S
R
G
A
G
S
A
Q
Site 102
S1045
G
R
S
R
G
A
G
S
A
Q
P
E
P
Q
H
Site 103
S1060
F
Q
P
K
K
H
N
S
Y
P
Q
P
P
Q
P
Site 104
Y1061
Q
P
K
K
H
N
S
Y
P
Q
P
P
Q
P
Y
Site 105
Y1068
Y
P
Q
P
P
Q
P
Y
P
A
Q
R
P
P
G
Site 106
Y1078
Q
R
P
P
G
P
R
Y
P
P
Y
T
T
P
P
Site 107
Y1081
P
G
P
R
Y
P
P
Y
T
T
P
P
R
M
R
Site 108
T1082
G
P
R
Y
P
P
Y
T
T
P
P
R
M
R
R
Site 109
T1083
P
R
Y
P
P
Y
T
T
P
P
R
M
R
R
Q
Site 110
S1092
P
R
M
R
R
Q
R
S
A
P
D
L
K
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation