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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF73
Full Name:
Zinc finger protein 73
Alias:
Cos12; Zinc finger 186; Zinc finger 73; ZNF186; ZNF2
Type:
Transcription protein. Krueppel C2H2-type zinc-finger protein family
Mass (Da):
38241
Number AA:
326
UniProt ID:
O43830
International Prot ID:
IPI00014491
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
K
K
V
H
I
G
Q
T
F
G
K
Y
N
E
Y
Site 2
Y17
I
G
Q
T
F
G
K
Y
N
E
Y
E
K
A
C
Site 3
Y20
T
F
G
K
Y
N
E
Y
E
K
A
C
N
N
L
Site 4
T41
I
T
Q
V
R
Q
P
T
C
C
R
K
S
D
F
Site 5
S70
C
V
E
C
E
K
P
S
I
S
K
S
D
L
M
Site 6
S72
E
C
E
K
P
S
I
S
K
S
D
L
M
I
Q
Site 7
S74
E
K
P
S
I
S
K
S
D
L
M
I
Q
H
K
Site 8
Y89
M
P
T
E
E
K
P
Y
A
C
N
C
C
E
K
Site 9
S99
N
C
C
E
K
L
F
S
Y
K
S
S
L
T
I
Site 10
Y100
C
C
E
K
L
F
S
Y
K
S
S
L
T
I
H
Site 11
S102
E
K
L
F
S
Y
K
S
S
L
T
I
H
Q
R
Site 12
S103
K
L
F
S
Y
K
S
S
L
T
I
H
Q
R
I
Site 13
T112
T
I
H
Q
R
I
H
T
G
E
K
P
Y
G
C
Site 14
Y117
I
H
T
G
E
K
P
Y
G
C
N
E
C
G
K
Site 15
S130
G
K
T
V
R
C
K
S
F
L
T
L
H
Q
R
Site 16
T133
V
R
C
K
S
F
L
T
L
H
Q
R
T
H
T
Site 17
T140
T
L
H
Q
R
T
H
T
G
D
K
P
Y
K
C
Site 18
Y145
T
H
T
G
D
K
P
Y
K
C
I
E
C
G
K
Site 19
T161
F
T
V
N
Q
L
L
T
L
H
H
R
T
H
S
Site 20
S168
T
L
H
H
R
T
H
S
G
E
K
P
Y
Q
C
Site 21
Y173
T
H
S
G
E
K
P
Y
Q
C
S
E
C
G
K
Site 22
S176
G
E
K
P
Y
Q
C
S
E
C
G
K
T
F
S
Site 23
T181
Q
C
S
E
C
G
K
T
F
S
Q
K
S
Y
L
Site 24
S183
S
E
C
G
K
T
F
S
Q
K
S
Y
L
T
I
Site 25
S186
G
K
T
F
S
Q
K
S
Y
L
T
I
H
H
R
Site 26
Y187
K
T
F
S
Q
K
S
Y
L
T
I
H
H
R
T
Site 27
T189
F
S
Q
K
S
Y
L
T
I
H
H
R
T
H
T
Site 28
T196
T
I
H
H
R
T
H
T
W
Q
K
P
Y
A
C
Site 29
S211
D
H
C
E
K
A
F
S
H
K
S
K
L
T
V
Site 30
S214
E
K
A
F
S
H
K
S
K
L
T
V
H
Q
R
Site 31
T217
F
S
H
K
S
K
L
T
V
H
Q
R
T
H
T
Site 32
T222
K
L
T
V
H
Q
R
T
H
T
G
E
K
P
Y
Site 33
T224
T
V
H
Q
R
T
H
T
G
E
K
P
Y
E
Y
Site 34
Y231
T
G
E
K
P
Y
E
Y
N
E
C
R
K
P
F
Site 35
S242
R
K
P
F
I
N
K
S
N
L
R
I
H
Q
R
Site 36
T250
N
L
R
I
H
Q
R
T
H
I
R
E
K
P
Y
Site 37
Y257
T
H
I
R
E
K
P
Y
E
C
N
E
C
G
K
Site 38
S270
G
K
T
F
H
Q
K
S
F
L
T
V
H
Q
R
Site 39
T273
F
H
Q
K
S
F
L
T
V
H
Q
R
T
H
R
Site 40
T278
F
L
T
V
H
Q
R
T
H
R
R
K
K
P
Y
Site 41
Y285
T
H
R
R
K
K
P
Y
E
C
N
E
L
G
K
Site 42
Y313
T
H
T
G
E
K
P
Y
A
C
N
K
C
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation