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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AKAP10
Full Name:
A-kinase anchor protein 10, mitochondrial
Alias:
A kinase (PRKA) anchor protein 10; A kinase anchor protein 10, mitochondrial; AKA10; D-AKAP2; D-AKAP-2; Dual specificity a kinase-anchoring protein 2; Dual-specificity A-kinase anchoring protein 2; MGC9414; Mitochondrial A kinase PPKA anchor protein 10; PRKA10; Protein kinase A anchoring protein 10; Protein kinase A-anchoring protein 10
Type:
Adaptor/scaffold
Mass (Da):
73820
Number AA:
UniProt ID:
O43572
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0008104
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
R
G
A
G
P
S
P
R
Q
S
P
R
T
Site 2
S11
A
G
P
S
P
R
Q
S
P
R
T
L
R
P
D
Site 3
T14
S
P
R
Q
S
P
R
T
L
R
P
D
P
G
P
Site 4
S24
P
D
P
G
P
A
M
S
F
F
R
R
K
V
K
Site 5
T38
K
G
K
E
Q
E
K
T
S
D
V
K
S
I
K
Site 6
S39
G
K
E
Q
E
K
T
S
D
V
K
S
I
K
A
Site 7
S43
E
K
T
S
D
V
K
S
I
K
A
S
I
S
V
Site 8
S47
D
V
K
S
I
K
A
S
I
S
V
H
S
P
Q
Site 9
S49
K
S
I
K
A
S
I
S
V
H
S
P
Q
K
S
Site 10
S52
K
A
S
I
S
V
H
S
P
Q
K
S
T
K
N
Site 11
S56
S
V
H
S
P
Q
K
S
T
K
N
H
A
L
L
Site 12
S82
A
I
S
A
N
M
D
S
F
S
S
S
R
T
A
Site 13
S84
S
A
N
M
D
S
F
S
S
S
R
T
A
T
L
Site 14
S85
A
N
M
D
S
F
S
S
S
R
T
A
T
L
K
Site 15
S86
N
M
D
S
F
S
S
S
R
T
A
T
L
K
K
Site 16
T88
D
S
F
S
S
S
R
T
A
T
L
K
K
Q
P
Site 17
T90
F
S
S
S
R
T
A
T
L
K
K
Q
P
S
H
Site 18
S96
A
T
L
K
K
Q
P
S
H
M
E
A
A
H
F
Site 19
Y113
L
G
R
S
C
L
D
Y
Q
T
Q
E
T
K
S
Site 20
T115
R
S
C
L
D
Y
Q
T
Q
E
T
K
S
S
L
Site 21
S121
Q
T
Q
E
T
K
S
S
L
S
K
T
L
E
Q
Site 22
T125
T
K
S
S
L
S
K
T
L
E
Q
V
L
H
D
Site 23
S163
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Site 24
T164
E
A
E
S
F
H
S
T
T
W
S
R
I
R
A
Site 25
S167
S
F
H
S
T
T
W
S
R
I
R
A
H
S
L
Site 26
S173
W
S
R
I
R
A
H
S
L
N
T
V
K
Q
S
Site 27
T176
I
R
A
H
S
L
N
T
V
K
Q
S
S
L
A
Site 28
S181
L
N
T
V
K
Q
S
S
L
A
E
P
V
S
P
Site 29
S187
S
S
L
A
E
P
V
S
P
S
K
K
H
E
T
Site 30
T194
S
P
S
K
K
H
E
T
T
A
S
F
L
T
D
Site 31
S197
K
K
H
E
T
T
A
S
F
L
T
D
S
L
D
Site 32
S202
T
A
S
F
L
T
D
S
L
D
K
R
L
E
D
Site 33
S210
L
D
K
R
L
E
D
S
G
S
A
Q
L
F
M
Site 34
S212
K
R
L
E
D
S
G
S
A
Q
L
F
M
T
H
Site 35
S220
A
Q
L
F
M
T
H
S
E
G
I
D
L
N
N
Site 36
T229
G
I
D
L
N
N
R
T
N
S
T
Q
N
H
L
Site 37
S231
D
L
N
N
R
T
N
S
T
Q
N
H
L
L
L
Site 38
S239
T
Q
N
H
L
L
L
S
Q
E
C
D
S
A
H
Site 39
S247
Q
E
C
D
S
A
H
S
L
R
L
E
M
A
R
Site 40
T257
L
E
M
A
R
A
G
T
H
Q
V
S
M
E
T
Site 41
S261
R
A
G
T
H
Q
V
S
M
E
T
Q
E
S
S
Site 42
T264
T
H
Q
V
S
M
E
T
Q
E
S
S
S
T
L
Site 43
S267
V
S
M
E
T
Q
E
S
S
S
T
L
T
V
A
Site 44
S269
M
E
T
Q
E
S
S
S
T
L
T
V
A
S
R
Site 45
T270
E
T
Q
E
S
S
S
T
L
T
V
A
S
R
N
Site 46
T272
Q
E
S
S
S
T
L
T
V
A
S
R
N
S
P
Site 47
S275
S
S
T
L
T
V
A
S
R
N
S
P
A
S
P
Site 48
S278
L
T
V
A
S
R
N
S
P
A
S
P
L
K
E
Site 49
S281
A
S
R
N
S
P
A
S
P
L
K
E
L
S
G
Site 50
S287
A
S
P
L
K
E
L
S
G
K
L
M
K
S
I
Site 51
S293
L
S
G
K
L
M
K
S
I
E
Q
D
A
V
N
Site 52
T303
Q
D
A
V
N
T
F
T
K
Y
I
S
P
D
A
Site 53
Y305
A
V
N
T
F
T
K
Y
I
S
P
D
A
A
K
Site 54
S307
N
T
F
T
K
Y
I
S
P
D
A
A
K
P
I
Site 55
Y368
R
S
H
H
F
C
K
Y
Q
I
E
V
L
T
S
Site 56
Y392
F
C
E
S
A
L
F
Y
F
S
E
Y
M
E
K
Site 57
Y439
Q
N
D
A
M
I
L
Y
D
K
Y
F
S
L
Q
Site 58
S444
I
L
Y
D
K
Y
F
S
L
Q
A
T
H
P
L
Site 59
T448
K
Y
F
S
L
Q
A
T
H
P
L
G
F
D
D
Site 60
S463
V
V
R
L
E
I
E
S
N
I
C
R
E
G
G
Site 61
T478
P
L
P
N
C
F
T
T
P
L
R
Q
A
W
T
Site 62
T486
P
L
R
Q
A
W
T
T
M
E
K
V
F
L
P
Site 63
Y501
G
F
L
S
S
N
L
Y
Y
K
Y
L
N
D
L
Site 64
Y504
S
S
N
L
Y
Y
K
Y
L
N
D
L
I
H
S
Site 65
S511
Y
L
N
D
L
I
H
S
V
R
G
D
E
F
L
Site 66
S529
V
S
L
T
A
P
G
S
V
G
P
P
D
E
S
Site 67
S536
S
V
G
P
P
D
E
S
H
P
G
S
S
D
S
Site 68
S540
P
D
E
S
H
P
G
S
S
D
S
S
A
S
Q
Site 69
S541
D
E
S
H
P
G
S
S
D
S
S
A
S
Q
S
Site 70
S543
S
H
P
G
S
S
D
S
S
A
S
Q
S
S
V
Site 71
S544
H
P
G
S
S
D
S
S
A
S
Q
S
S
V
K
Site 72
S546
G
S
S
D
S
S
A
S
Q
S
S
V
K
K
A
Site 73
S548
S
D
S
S
A
S
Q
S
S
V
K
K
A
S
I
Site 74
S549
D
S
S
A
S
Q
S
S
V
K
K
A
S
I
K
Site 75
S576
A
A
S
L
D
P
E
S
L
Y
Q
R
T
Y
A
Site 76
Y578
S
L
D
P
E
S
L
Y
Q
R
T
Y
A
G
K
Site 77
Y582
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Site 78
T587
R
T
Y
A
G
K
M
T
F
G
R
V
S
D
L
Site 79
S592
K
M
T
F
G
R
V
S
D
L
G
Q
F
I
R
Site 80
S601
L
G
Q
F
I
R
E
S
E
P
E
P
D
V
R
Site 81
S610
P
E
P
D
V
R
K
S
K
G
S
M
F
S
Q
Site 82
S613
D
V
R
K
S
K
G
S
M
F
S
Q
A
M
K
Site 83
S616
K
S
K
G
S
M
F
S
Q
A
M
K
K
W
V
Site 84
Y652
D
I
M
Q
Q
A
Q
Y
D
Q
P
L
E
K
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation