PhosphoNET

           
Protein Info 
   
Short Name:  FRS3
Full Name:  Fibroblast growth factor receptor substrate 3
Alias:  FRS2B; FRS2beta; MGC17167; SNT2; SNT-2
Type:  Membrane protein
Mass (Da):  54462
Number AA:  492
UniProt ID:  O43559
International Prot ID:  IPI00009089
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0031225     Uniprot OncoNet
Molecular Function:  GO:0005104  GO:0005158   PhosphoSite+ KinaseNET
Biological Process:  GO:0008543     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12CSCLNRDSVPDNHPT
Site 2Y59REAVRWPYLCLRRYG
Site 3Y65PYLCLRRYGYDSNLF
Site 4Y67LCLRRYGYDSNLFSF
Site 5S69LRRYGYDSNLFSFES
Site 6S73GYDSNLFSFESGRRC
Site 7S76SNLFSFESGRRCQTG
Site 8T82ESGRRCQTGQGIFAF
Site 9S123PVIITRNSHPAELDL
Site 10Y142QPPNALGYTVSSFSN
Site 11T143PPNALGYTVSSFSNG
Site 12S145NALGYTVSSFSNGCP
Site 13S148GYTVSSFSNGCPGEG
Site 14S159PGEGPRFSAPRRLST
Site 15S165FSAPRRLSTSSLRHP
Site 16T166SAPRRLSTSSLRHPS
Site 17S167APRRLSTSSLRHPSL
Site 18S168PRRLSTSSLRHPSLG
Site 19S173TSSLRHPSLGEESTH
Site 20S189LIAPDEQSHTYVNTP
Site 21T191APDEQSHTYVNTPAS
Site 22Y192PDEQSHTYVNTPASE
Site 23T195QSHTYVNTPASEDDH
Site 24S198TYVNTPASEDDHRRG
Site 25Y287PAQPKCTYENVTGGL
Site 26S303RGAGWRLSPEEPGWN
Site 27Y322RRAALLHYENLPPLP
Site 28S334PLPPVWESQAQQLGG
Site 29S349EAGDDGDSRDGLTPS
Site 30T354GDSRDGLTPSSNGFP
Site 31S356SRDGLTPSSNGFPDG
Site 32S357RDGLTPSSNGFPDGE
Site 33T368PDGEEDETPLQKPTS
Site 34S375TPLQKPTSTRAAIRS
Site 35S382STRAAIRSHGSFPVP
Site 36S385AAIRSHGSFPVPLTR
Site 37T391GSFPVPLTRRRGSPR
Site 38S396PLTRRRGSPRVFNFD
Site 39Y417EPPRQLNYIQVELKG
Site 40S437PKGPQNPSSPQAPMP
Site 41S438KGPQNPSSPQAPMPT
Site 42T445SPQAPMPTTHPARSS
Site 43T446PQAPMPTTHPARSSD
Site 44S452TTHPARSSDSYAVID
Site 45S454HPARSSDSYAVIDLK
Site 46Y455PARSSDSYAVIDLKK
Site 47T479ALPRDDGTARKTRHN
Site 48T483DDGTARKTRHNSTDL
Site 49S487ARKTRHNSTDLPL__
Site 50T488RKTRHNSTDLPL___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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