PhosphoNET

           
Protein Info 
   
Short Name:  WIP
Full Name:  WAS/WASL-interacting protein family member 1
Alias:  PRPL-2; WAIP; WAS/WASL interacting protein family, member 1; WASIP; Wasp interacting protein; WASPIP; WIPF1
Type:  Actin binding protein
Mass (Da):  51275
Number AA:  503
UniProt ID:  O43516
International Prot ID:  IPI00418328
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016023  GO:0005730   Uniprot OncoNet
Molecular Function:  GO:0003779  GO:0005522   PhosphoSite+ KinaseNET
Biological Process:  GO:0008154  GO:0006461   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T14PAPPPPPTFALANTE
Site 2T20PTFALANTEKPTLNK
Site 3S38AGRNALLSDISKGKK
Site 4S41NALLSDISKGKKLKK
Site 5T49KGKKLKKTVTNDRSA
Site 6T51KKLKKTVTNDRSAPI
Site 7S91GGGGGGGSFGGGGPP
Site 8T114GMPKLRSTANRDNDS
Site 9S121TANRDNDSGGSRPPL
Site 10S135LLPPGGRSTSAKPFS
Site 11T136LPPGGRSTSAKPFSP
Site 12S137PPGGRSTSAKPFSPP
Site 13S142STSAKPFSPPSGPGR
Site 14S145AKPFSPPSGPGRFPV
Site 15S154PGRFPVPSPGHRSGP
Site 16S159VPSPGHRSGPPEPQR
Site 17S178PPRPDVGSKPDSIPP
Site 18S182DVGSKPDSIPPPVPS
Site 19S189SIPPPVPSTPRPIQS
Site 20T190IPPPVPSTPRPIQSS
Site 21S196STPRPIQSSLHNRGS
Site 22S197TPRPIQSSLHNRGSP
Site 23S203SSLHNRGSPPVPGGP
Site 24S214PGGPRQPSPGPTPPP
Site 25T218RQPSPGPTPPPFPGN
Site 26T228PFPGNRGTALGGGSI
Site 27S234GTALGGGSIRQSPLS
Site 28S238GGGSIRQSPLSSSSP
Site 29S241SIRQSPLSSSSPFSN
Site 30S242IRQSPLSSSSPFSNR
Site 31S243RQSPLSSSSPFSNRP
Site 32S244QSPLSSSSPFSNRPP
Site 33S247LSSSSPFSNRPPLPP
Site 34T255NRPPLPPTPSRALDD
Site 35S257PPLPPTPSRALDDKP
Site 36S276PPVGNRPSIHREAVP
Site 37S296NNKPPVPSTPRPSAS
Site 38T297NKPPVPSTPRPSASS
Site 39S301VPSTPRPSASSQAPP
Site 40S303STPRPSASSQAPPPP
Site 41S304TPRPSASSQAPPPPP
Site 42S314PPPPPPPSRPGPPPL
Site 43S324GPPPLPPSSSGNDET
Site 44S325PPPLPPSSSGNDETP
Site 45S326PPLPPSSSGNDETPR
Site 46T331SSSGNDETPRLPQRN
Site 47S340RLPQRNLSLSSSTPP
Site 48S342PQRNLSLSSSTPPLP
Site 49S343QRNLSLSSSTPPLPS
Site 50S344RNLSLSSSTPPLPSP
Site 51T345NLSLSSSTPPLPSPG
Site 52S350SSTPPLPSPGRSGPL
Site 53S354PLPSPGRSGPLPPPP
Site 54S362GPLPPPPSERPPPPV
Site 55S376VRDPPGRSGPLPPPP
Site 56S386LPPPPPVSRNGSTSR
Site 57S390PPVSRNGSTSRALPA
Site 58T391PVSRNGSTSRALPAT
Site 59S392VSRNGSTSRALPATP
Site 60T398TSRALPATPQLPSRS
Site 61S403PATPQLPSRSGVDSP
Site 62S405TPQLPSRSGVDSPRS
Site 63S409PSRSGVDSPRSGPRP
Site 64S412SGVDSPRSGPRPPLP
Site 65S424PLPPDRPSAGAPPPP
Site 66S434APPPPPPSTSIRNGF
Site 67T435PPPPPPSTSIRNGFQ
Site 68S436PPPPPSTSIRNGFQD
Site 69S444IRNGFQDSPCEDEWE
Site 70Y455DEWESRFYFHPISDL
Site 71S460RFYFHPISDLPPPEP
Site 72Y468DLPPPEPYVQTTKSY
Site 73S474PYVQTTKSYPSKLAR
Site 74Y475YVQTTKSYPSKLARN
Site 75S484SKLARNESRSGSNRR
Site 76S486LARNESRSGSNRRER
Site 77S488RNESRSGSNRRERGA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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