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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AKR7A2
Full Name:
Aflatoxin B1 aldehyde reductase member 2
Alias:
AFAR; AFAR1; AFB1-AR 1; AFB1-AR1; Aflatoxin aldehyde reductase; Aflatoxin beta1 aldehyde reductase; AKR7; Aldo-keto reductase family 7, member A2; Aldoketoreductase 7; ARK72; EC 1.-.-.-
Type:
Oxidoreductase; EC 1.-.-.-
Mass (Da):
39589
Number AA:
359
UniProt ID:
O43488
International Prot ID:
IPI00305978
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0004032
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0005975
GO:0006081
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
A
V
H
C
A
L
R
S
P
P
P
E
A
R
A
Site 2
S31
E
A
R
A
L
A
M
S
R
P
P
P
P
R
V
Site 3
T44
R
V
A
S
V
L
G
T
M
E
M
G
R
R
M
Site 4
S56
R
R
M
D
A
P
A
S
A
A
A
V
R
A
F
Site 5
T69
A
F
L
E
R
G
H
T
E
L
D
T
A
F
M
Site 6
T73
R
G
H
T
E
L
D
T
A
F
M
Y
S
D
G
Site 7
Y77
E
L
D
T
A
F
M
Y
S
D
G
Q
S
E
T
Site 8
S78
L
D
T
A
F
M
Y
S
D
G
Q
S
E
T
I
Site 9
S82
F
M
Y
S
D
G
Q
S
E
T
I
L
G
G
L
Site 10
T104
D
C
R
V
K
I
A
T
K
A
N
P
W
D
G
Site 11
S113
A
N
P
W
D
G
K
S
L
K
P
D
S
V
R
Site 12
S118
G
K
S
L
K
P
D
S
V
R
S
Q
L
E
T
Site 13
S121
L
K
P
D
S
V
R
S
Q
L
E
T
S
L
K
Site 14
T125
S
V
R
S
Q
L
E
T
S
L
K
R
L
Q
C
Site 15
S126
V
R
S
Q
L
E
T
S
L
K
R
L
Q
C
P
Site 16
Y139
C
P
Q
V
D
L
F
Y
L
H
A
P
D
H
G
Site 17
T147
L
H
A
P
D
H
G
T
P
V
E
E
T
L
H
Site 18
S171
K
F
V
E
L
G
L
S
N
Y
A
S
W
E
V
Site 19
Y173
V
E
L
G
L
S
N
Y
A
S
W
E
V
A
E
Site 20
Y223
R
H
F
G
L
R
F
Y
A
Y
N
P
L
A
G
Site 21
Y225
F
G
L
R
F
Y
A
Y
N
P
L
A
G
G
L
Site 22
Y237
G
G
L
L
T
G
K
Y
K
Y
E
D
K
D
G
Site 23
Y239
L
L
T
G
K
Y
K
Y
E
D
K
D
G
K
Q
Site 24
S255
V
G
R
F
F
G
N
S
W
A
E
T
Y
R
N
Site 25
Y260
G
N
S
W
A
E
T
Y
R
N
R
F
W
K
E
Site 26
Y300
S
A
A
L
R
W
M
Y
H
H
S
Q
L
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation