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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CBFA2T2
Full Name:
Protein CBFA2T2
Alias:
Core-binding factor, runt domain, alpha subunit 2; EHT; ETO homologous on chromosome 20; MT8R; MTG8-like protein; MTG8R; MTG8-related protein 1; MTGR1; Myeloid translocation related protein 1; P85; Translocated to, 2; ZMYND3
Type:
Transcription, coactivator/corepressor
Mass (Da):
67133
Number AA:
604
UniProt ID:
O43439
International Prot ID:
IPI00179452
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
R
V
P
A
M
P
G
S
P
V
E
V
K
I
Q
Site 2
S41
P
V
E
V
K
I
Q
S
R
S
S
P
P
T
M
Site 3
S43
E
V
K
I
Q
S
R
S
S
P
P
T
M
P
P
Site 4
S44
V
K
I
Q
S
R
S
S
P
P
T
M
P
P
L
Site 5
T47
Q
S
R
S
S
P
P
T
M
P
P
L
P
P
I
Site 6
S63
P
G
G
P
R
P
V
S
F
T
P
T
A
L
S
Site 7
T65
G
P
R
P
V
S
F
T
P
T
A
L
S
N
G
Site 8
T67
R
P
V
S
F
T
P
T
A
L
S
N
G
I
N
Site 9
S70
S
F
T
P
T
A
L
S
N
G
I
N
H
S
P
Site 10
S76
L
S
N
G
I
N
H
S
P
P
T
L
N
G
A
Site 11
T79
G
I
N
H
S
P
P
T
L
N
G
A
P
S
P
Site 12
S85
P
T
L
N
G
A
P
S
P
P
Q
R
F
S
N
Site 13
S91
P
S
P
P
Q
R
F
S
N
G
P
A
S
S
T
Site 14
S96
R
F
S
N
G
P
A
S
S
T
S
S
A
L
T
Site 15
S97
F
S
N
G
P
A
S
S
T
S
S
A
L
T
N
Site 16
S100
G
P
A
S
S
T
S
S
A
L
T
N
Q
Q
L
Site 17
T103
S
S
T
S
S
A
L
T
N
Q
Q
L
P
A
T
Site 18
S117
T
C
G
A
R
Q
L
S
K
L
K
R
F
L
T
Site 19
T124
S
K
L
K
R
F
L
T
T
L
Q
Q
F
G
N
Site 20
T125
K
L
K
R
F
L
T
T
L
Q
Q
F
G
N
D
Site 21
S134
Q
Q
F
G
N
D
I
S
P
E
I
G
E
K
V
Site 22
T199
C
A
R
A
A
K
Q
T
P
S
Q
Y
L
A
Q
Site 23
S201
R
A
A
K
Q
T
P
S
Q
Y
L
A
Q
H
E
Site 24
Y203
A
K
Q
T
P
S
Q
Y
L
A
Q
H
E
H
L
Site 25
S215
E
H
L
L
L
N
T
S
I
A
S
P
A
D
S
Site 26
S218
L
L
N
T
S
I
A
S
P
A
D
S
S
E
L
Site 27
S237
H
G
N
G
K
R
P
S
P
E
R
R
E
E
N
Site 28
S245
P
E
R
R
E
E
N
S
F
D
R
D
T
I
A
Site 29
T250
E
N
S
F
D
R
D
T
I
A
P
E
P
P
A
Site 30
T262
P
P
A
K
R
V
C
T
I
S
P
A
P
R
H
Site 31
S264
A
K
R
V
C
T
I
S
P
A
P
R
H
S
P
Site 32
T274
P
R
H
S
P
A
L
T
V
P
L
M
N
P
G
Site 33
T287
P
G
G
Q
F
H
P
T
P
P
P
L
Q
H
Y
Site 34
T295
P
P
P
L
Q
H
Y
T
L
E
D
I
A
T
S
Site 35
T301
Y
T
L
E
D
I
A
T
S
H
L
Y
R
E
P
Site 36
Y305
D
I
A
T
S
H
L
Y
R
E
P
N
K
M
L
Site 37
S323
E
V
R
D
R
H
H
S
L
G
L
N
G
G
Y
Site 38
T340
E
L
V
D
H
R
L
T
E
R
E
W
A
D
E
Site 39
S368
M
V
E
K
T
R
R
S
M
A
V
L
R
R
C
Site 40
S378
V
L
R
R
C
Q
E
S
D
R
E
E
L
N
Y
Site 41
Y385
S
D
R
E
E
L
N
Y
W
K
R
R
Y
N
E
Site 42
Y390
L
N
Y
W
K
R
R
Y
N
E
N
T
E
L
R
Site 43
T394
K
R
R
Y
N
E
N
T
E
L
R
K
T
G
T
Site 44
T399
E
N
T
E
L
R
K
T
G
T
E
L
V
S
R
Site 45
T401
T
E
L
R
K
T
G
T
E
L
V
S
R
Q
H
Site 46
S405
K
T
G
T
E
L
V
S
R
Q
H
S
P
G
S
Site 47
S409
E
L
V
S
R
Q
H
S
P
G
S
A
D
S
L
Site 48
S412
S
R
Q
H
S
P
G
S
A
D
S
L
S
N
D
Site 49
S415
H
S
P
G
S
A
D
S
L
S
N
D
S
Q
R
Site 50
S417
P
G
S
A
D
S
L
S
N
D
S
Q
R
E
F
Site 51
S420
A
D
S
L
S
N
D
S
Q
R
E
F
N
S
R
Site 52
S426
D
S
Q
R
E
F
N
S
R
P
G
T
G
Y
V
Site 53
T430
E
F
N
S
R
P
G
T
G
Y
V
P
V
E
F
Site 54
Y432
N
S
R
P
G
T
G
Y
V
P
V
E
F
W
K
Site 55
T473
K
A
F
E
V
I
A
T
E
R
A
R
M
E
Q
Site 56
T517
C
G
R
K
A
S
E
T
C
S
G
C
N
I
A
Site 57
S519
R
K
A
S
E
T
C
S
G
C
N
I
A
R
Y
Site 58
S551
G
Q
N
L
H
G
Q
S
P
H
G
Q
G
R
P
Site 59
S566
L
L
P
V
G
R
G
S
S
A
R
S
A
D
C
Site 60
S567
L
P
V
G
R
G
S
S
A
R
S
A
D
C
S
Site 61
S570
G
R
G
S
S
A
R
S
A
D
C
S
V
P
S
Site 62
S574
S
A
R
S
A
D
C
S
V
P
S
P
A
L
D
Site 63
S577
S
A
D
C
S
V
P
S
P
A
L
D
K
T
S
Site 64
T583
P
S
P
A
L
D
K
T
S
A
T
T
S
R
S
Site 65
S584
S
P
A
L
D
K
T
S
A
T
T
S
R
S
S
Site 66
T586
A
L
D
K
T
S
A
T
T
S
R
S
S
T
P
Site 67
T587
L
D
K
T
S
A
T
T
S
R
S
S
T
P
A
Site 68
S588
D
K
T
S
A
T
T
S
R
S
S
T
P
A
S
Site 69
S590
T
S
A
T
T
S
R
S
S
T
P
A
S
V
T
Site 70
S591
S
A
T
T
S
R
S
S
T
P
A
S
V
T
A
Site 71
T592
A
T
T
S
R
S
S
T
P
A
S
V
T
A
I
Site 72
S595
S
R
S
S
T
P
A
S
V
T
A
I
D
T
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation