KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
HNRNPR
Full Name:
Heterogeneous nuclear ribonucleoprotein R
Alias:
hnRNP-R; HNRPR; HNRPR protein (Heterogeneous nuclear ribonucleoprotein R)
Type:
RNA binding protein
Mass (Da):
70943
Number AA:
633
UniProt ID:
O43390
International Prot ID:
IPI00012074
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030530
GO:0005654
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
E
E
E
E
P
M
D
T
S
S
V
T
H
T
E
Site 2
S23
E
E
P
M
D
T
S
S
V
T
H
T
E
H
Y
Site 3
T27
D
T
S
S
V
T
H
T
E
H
Y
K
T
L
I
Site 4
T32
T
H
T
E
H
Y
K
T
L
I
E
A
G
L
P
Site 5
S78
F
N
E
E
G
A
L
S
V
L
Q
Q
F
K
E
Site 6
S89
Q
F
K
E
S
D
L
S
H
V
Q
N
K
S
A
Site 7
T104
F
L
C
G
V
M
K
T
Y
R
Q
R
E
K
Q
Site 8
S113
R
Q
R
E
K
Q
G
S
K
V
Q
E
S
T
K
Site 9
T141
T
G
Y
T
L
D
V
T
T
G
Q
R
K
Y
G
Site 10
T142
G
Y
T
L
D
V
T
T
G
Q
R
K
Y
G
G
Site 11
Y147
V
T
T
G
Q
R
K
Y
G
G
P
P
P
D
S
Site 12
S154
Y
G
G
P
P
P
D
S
V
Y
S
G
V
Q
P
Site 13
Y156
G
P
P
P
D
S
V
Y
S
G
V
Q
P
G
I
Site 14
S157
P
P
P
D
S
V
Y
S
G
V
Q
P
G
I
G
Site 15
Y177
G
K
I
P
R
D
L
Y
E
D
E
L
V
P
L
Site 16
S202
R
L
M
M
D
P
L
S
G
Q
N
R
G
Y
A
Site 17
Y208
L
S
G
Q
N
R
G
Y
A
F
I
T
F
C
G
Site 18
T212
N
R
G
Y
A
F
I
T
F
C
G
K
E
A
A
Site 19
S228
E
A
V
K
L
C
D
S
Y
E
I
R
P
G
K
Site 20
Y229
A
V
K
L
C
D
S
Y
E
I
R
P
G
K
H
Site 21
S252
N
N
R
L
F
V
G
S
I
P
K
N
K
T
K
Site 22
T258
G
S
I
P
K
N
K
T
K
E
N
I
L
E
E
Site 23
Y279
G
L
V
D
V
I
L
Y
H
Q
P
D
D
K
K
Site 24
Y296
R
G
F
C
F
L
E
Y
E
D
H
K
S
A
A
Site 25
S301
L
E
Y
E
D
H
K
S
A
A
Q
A
R
R
R
Site 26
S311
Q
A
R
R
R
L
M
S
G
K
V
K
V
W
G
Site 27
S360
T
E
E
I
L
E
K
S
F
S
E
F
G
K
L
Site 28
S362
E
I
L
E
K
S
F
S
E
F
G
K
L
E
R
Site 29
Y376
R
V
K
K
L
K
D
Y
A
F
V
H
F
E
D
Site 30
S426
R
Q
A
A
R
Q
A
S
R
S
T
A
Y
E
D
Site 31
S428
A
A
R
Q
A
S
R
S
T
A
Y
E
D
Y
Y
Site 32
T429
A
R
Q
A
S
R
S
T
A
Y
E
D
Y
Y
Y
Site 33
Y431
Q
A
S
R
S
T
A
Y
E
D
Y
Y
Y
H
P
Site 34
Y434
R
S
T
A
Y
E
D
Y
Y
Y
H
P
P
P
R
Site 35
Y435
S
T
A
Y
E
D
Y
Y
Y
H
P
P
P
R
M
Site 36
Y436
T
A
Y
E
D
Y
Y
Y
H
P
P
P
R
M
P
Site 37
Y458
R
G
G
G
R
G
G
Y
G
Y
P
P
D
Y
Y
Site 38
Y460
G
G
R
G
G
Y
G
Y
P
P
D
Y
Y
G
Y
Site 39
Y464
G
Y
G
Y
P
P
D
Y
Y
G
Y
E
D
Y
Y
Site 40
Y465
Y
G
Y
P
P
D
Y
Y
G
Y
E
D
Y
Y
D
Site 41
Y470
D
Y
Y
G
Y
E
D
Y
Y
D
D
Y
Y
G
Y
Site 42
Y471
Y
Y
G
Y
E
D
Y
Y
D
D
Y
Y
G
Y
D
Site 43
Y474
Y
E
D
Y
Y
D
D
Y
Y
G
Y
D
Y
H
D
Site 44
Y475
E
D
Y
Y
D
D
Y
Y
G
Y
D
Y
H
D
Y
Site 45
Y477
Y
Y
D
D
Y
Y
G
Y
D
Y
H
D
Y
R
G
Site 46
Y479
D
D
Y
Y
G
Y
D
Y
H
D
Y
R
G
G
Y
Site 47
Y482
Y
G
Y
D
Y
H
D
Y
R
G
G
Y
E
D
P
Site 48
Y486
Y
H
D
Y
R
G
G
Y
E
D
P
Y
Y
G
Y
Site 49
Y490
R
G
G
Y
E
D
P
Y
Y
G
Y
D
D
G
Y
Site 50
Y491
G
G
Y
E
D
P
Y
Y
G
Y
D
D
G
Y
A
Site 51
Y497
Y
Y
G
Y
D
D
G
Y
A
V
R
G
R
G
G
Site 52
Y529
P
P
R
G
R
A
G
Y
S
Q
R
G
A
P
L
Site 53
S530
P
R
G
R
A
G
Y
S
Q
R
G
A
P
L
G
Site 54
S542
P
L
G
P
P
R
G
S
R
G
G
R
G
G
P
Site 55
S558
Q
Q
Q
R
G
R
G
S
R
G
S
R
G
N
R
Site 56
S561
R
G
R
G
S
R
G
S
R
G
N
R
G
G
N
Site 57
Y578
G
K
R
K
A
D
G
Y
N
Q
P
D
S
K
R
Site 58
S583
D
G
Y
N
Q
P
D
S
K
R
R
Q
T
N
N
Site 59
T588
P
D
S
K
R
R
Q
T
N
N
Q
Q
N
W
G
Site 60
Y610
P
L
Q
Q
G
G
D
Y
S
G
N
Y
G
Y
N
Site 61
Y614
G
G
D
Y
S
G
N
Y
G
Y
N
N
D
N
Q
Site 62
Y616
D
Y
S
G
N
Y
G
Y
N
N
D
N
Q
E
F
Site 63
Y624
N
N
D
N
Q
E
F
Y
Q
D
T
Y
G
Q
Q
Site 64
T627
N
Q
E
F
Y
Q
D
T
Y
G
Q
Q
W
K
_
Site 65
Y628
Q
E
F
Y
Q
D
T
Y
G
Q
Q
W
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation