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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0427
Full Name:
CBP80/20-dependent translation initiation factor
Alias:
K0427; kiaa0427; Protein
Type:
Mass (Da):
67587
Number AA:
598
UniProt ID:
O43310
International Prot ID:
IPI00604690
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000184
GO:0006446
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
N
S
S
A
A
S
A
S
S
E
Site 2
S8
M
E
N
S
S
A
A
S
A
S
S
E
A
G
S
Site 3
S10
S
E
A
G
S
S
R
S
Q
E
I
E
E
L
E
Site 4
S11
S
S
A
A
S
A
S
S
E
A
G
S
S
R
S
Site 5
S15
S
A
S
S
E
A
G
S
S
R
S
Q
E
I
E
Site 6
S16
A
S
S
E
A
G
S
S
R
S
Q
E
I
E
E
Site 7
S18
S
E
A
G
S
S
R
S
Q
E
I
E
E
L
E
Site 8
Y31
L
E
R
F
I
D
S
Y
V
L
E
Y
Q
V
Q
Site 9
T45
Q
G
L
L
A
D
K
T
E
G
D
G
E
S
E
Site 10
S51
K
T
E
G
D
G
E
S
E
R
T
Q
S
H
I
Site 11
T54
G
D
G
E
S
E
R
T
Q
S
H
I
S
Q
W
Site 12
S56
G
E
S
E
R
T
Q
S
H
I
S
Q
W
T
A
Site 13
S59
E
R
T
Q
S
H
I
S
Q
W
T
A
D
C
S
Site 14
S66
S
Q
W
T
A
D
C
S
E
P
L
D
S
S
C
Site 15
S71
D
C
S
E
P
L
D
S
S
C
S
F
S
R
G
Site 16
S72
C
S
E
P
L
D
S
S
C
S
F
S
R
G
R
Site 17
S74
E
P
L
D
S
S
C
S
F
S
R
G
R
A
P
Site 18
S76
L
D
S
S
C
S
F
S
R
G
R
A
P
P
Q
Site 19
S87
A
P
P
Q
Q
N
G
S
K
D
N
S
L
D
M
Site 20
S91
Q
N
G
S
K
D
N
S
L
D
M
L
G
T
D
Site 21
T104
T
D
I
W
A
A
N
T
F
D
S
F
S
G
A
Site 22
S109
A
N
T
F
D
S
F
S
G
A
T
W
D
L
Q
Site 23
T123
Q
P
E
K
L
D
F
T
Q
F
H
R
K
V
R
Site 24
T132
F
H
R
K
V
R
H
T
P
K
Q
P
L
P
H
Site 25
T183
H
E
V
E
I
A
H
T
K
K
L
F
R
R
R
Site 26
S216
H
G
D
H
Q
P
G
S
A
K
H
N
R
D
H
Site 27
S226
H
N
R
D
H
Q
K
S
Y
Q
G
G
S
A
P
Site 28
Y227
N
R
D
H
Q
K
S
Y
Q
G
G
S
A
P
H
Site 29
S231
Q
K
S
Y
Q
G
G
S
A
P
H
P
S
G
R
Site 30
S236
G
G
S
A
P
H
P
S
G
R
P
T
H
H
G
Site 31
T240
P
H
P
S
G
R
P
T
H
H
G
Y
S
Q
N
Site 32
T274
A
H
R
N
A
K
E
T
M
T
I
E
N
P
K
Site 33
T285
E
N
P
K
L
E
D
T
A
G
D
T
G
H
S
Site 34
T289
L
E
D
T
A
G
D
T
G
H
S
S
L
E
A
Site 35
S293
A
G
D
T
G
H
S
S
L
E
A
P
R
S
P
Site 36
S299
S
S
L
E
A
P
R
S
P
D
T
L
A
P
V
Site 37
T302
E
A
P
R
S
P
D
T
L
A
P
V
A
S
E
Site 38
S308
D
T
L
A
P
V
A
S
E
R
L
P
P
Q
Q
Site 39
S316
E
R
L
P
P
Q
Q
S
G
G
P
E
V
E
T
Site 40
T323
S
G
G
P
E
V
E
T
K
R
K
D
S
I
L
Site 41
S328
V
E
T
K
R
K
D
S
I
L
P
E
R
I
G
Site 42
T341
I
G
E
R
P
K
I
T
L
L
Q
S
S
K
D
Site 43
S345
P
K
I
T
L
L
Q
S
S
K
D
R
L
R
R
Site 44
T366
E
V
A
V
E
T
T
T
P
Q
Q
N
K
M
D
Site 45
S381
K
L
I
E
I
L
N
S
M
R
N
N
S
S
D
Site 46
S386
L
N
S
M
R
N
N
S
S
D
V
D
T
K
L
Site 47
T391
N
N
S
S
D
V
D
T
K
L
T
T
F
M
E
Site 48
T395
D
V
D
T
K
L
T
T
F
M
E
E
A
Q
N
Site 49
S403
F
M
E
E
A
Q
N
S
T
N
S
E
E
M
L
Site 50
Y418
G
E
I
V
R
T
I
Y
Q
K
A
V
S
D
R
Site 51
S423
T
I
Y
Q
K
A
V
S
D
R
S
F
A
F
T
Site 52
S426
Q
K
A
V
S
D
R
S
F
A
F
T
A
A
K
Site 53
T430
S
D
R
S
F
A
F
T
A
A
K
L
C
D
K
Site 54
T461
N
M
L
Q
K
D
F
T
V
R
E
E
L
Q
Q
Site 55
S490
E
V
F
G
T
M
R
S
S
T
G
E
P
F
R
Site 56
S491
V
F
G
T
M
R
S
S
T
G
E
P
F
R
V
Site 57
T492
F
G
T
M
R
S
S
T
G
E
P
F
R
V
L
Site 58
S513
C
L
R
E
L
L
Q
S
Q
D
V
K
E
D
A
Site 59
T531
C
S
M
E
L
Q
S
T
G
R
L
L
E
E
Q
Site 60
S558
R
D
K
M
L
C
P
S
E
S
M
L
T
R
S
Site 61
T582
A
N
S
W
N
P
L
T
P
P
I
T
Q
Y
Y
Site 62
T586
N
P
L
T
P
P
I
T
Q
Y
Y
N
R
T
I
Site 63
Y588
L
T
P
P
I
T
Q
Y
Y
N
R
T
I
Q
K
Site 64
Y589
T
P
P
I
T
Q
Y
Y
N
R
T
I
Q
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation