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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEC14L5
Full Name:
SEC14-like protein 5
Alias:
Type:
Mass (Da):
78942
Number AA:
696
UniProt ID:
O43304
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
Y
Q
S
P
V
R
V
Y
K
Y
P
F
E
L
V
Site 2
Y23
F
E
L
V
M
A
A
Y
E
K
R
F
P
T
C
Site 3
T29
A
Y
E
K
R
F
P
T
C
P
Q
I
P
V
F
Site 4
S39
Q
I
P
V
F
L
G
S
E
V
L
R
E
S
R
Site 5
S45
G
S
E
V
L
R
E
S
R
S
P
D
G
A
V
Site 6
S47
E
V
L
R
E
S
R
S
P
D
G
A
V
H
V
Site 7
Y114
V
V
N
E
H
C
S
Y
T
V
H
P
E
N
E
Site 8
S131
T
C
F
E
Q
S
A
S
L
D
I
R
S
F
F
Site 9
S136
S
A
S
L
D
I
R
S
F
F
G
F
E
N
A
Site 10
Y166
G
K
E
V
I
E
H
Y
L
N
E
L
I
S
Q
Site 11
S172
H
Y
L
N
E
L
I
S
Q
G
T
S
H
I
P
Site 12
S176
E
L
I
S
Q
G
T
S
H
I
P
R
W
T
P
Site 13
T182
T
S
H
I
P
R
W
T
P
A
P
V
R
E
E
Site 14
S201
Q
A
G
P
R
D
P
S
S
L
E
A
H
G
P
Site 15
S202
A
G
P
R
D
P
S
S
L
E
A
H
G
P
R
Site 16
S210
L
E
A
H
G
P
R
S
T
L
G
P
A
L
E
Site 17
T211
E
A
H
G
P
R
S
T
L
G
P
A
L
E
A
Site 18
Y230
G
D
K
L
D
A
D
Y
I
E
R
C
L
G
H
Site 19
T239
E
R
C
L
G
H
L
T
P
M
Q
E
S
C
L
Site 20
S288
A
R
E
M
L
R
Q
S
L
S
W
R
K
Q
H
Site 21
S290
E
M
L
R
Q
S
L
S
W
R
K
Q
H
Q
V
Site 22
Y314
P
A
L
L
E
E
F
Y
A
G
G
W
H
Y
Q
Site 23
Y320
F
Y
A
G
G
W
H
Y
Q
D
I
D
G
R
P
Site 24
Y329
D
I
D
G
R
P
L
Y
I
L
R
L
G
Q
M
Site 25
S356
A
L
L
R
H
V
L
S
V
N
E
E
G
Q
K
Site 26
S368
G
Q
K
R
C
E
G
S
T
R
Q
L
G
R
P
Site 27
S377
R
Q
L
G
R
P
I
S
S
W
T
C
L
L
D
Site 28
Y412
I
E
V
V
E
D
N
Y
P
E
T
L
G
R
L
Site 29
T443
S
P
F
I
N
E
N
T
R
R
K
F
L
I
Y
Site 30
Y450
T
R
R
K
F
L
I
Y
S
G
S
N
Y
Q
G
Site 31
S453
K
F
L
I
Y
S
G
S
N
Y
Q
G
P
G
G
Site 32
Y455
L
I
Y
S
G
S
N
Y
Q
G
P
G
G
L
V
Site 33
Y464
G
P
G
G
L
V
D
Y
L
D
R
E
V
I
P
Site 34
S478
P
D
F
L
G
G
E
S
V
C
N
V
P
E
G
Site 35
S491
E
G
G
L
V
P
K
S
L
Y
M
T
E
E
E
Site 36
Y493
G
L
V
P
K
S
L
Y
M
T
E
E
E
Q
E
Site 37
T495
V
P
K
S
L
Y
M
T
E
E
E
Q
E
H
T
Site 38
Y512
L
W
Q
W
S
E
T
Y
H
S
A
S
V
L
R
Site 39
S514
Q
W
S
E
T
Y
H
S
A
S
V
L
R
G
A
Site 40
S516
S
E
T
Y
H
S
A
S
V
L
R
G
A
P
H
Site 41
S550
L
R
G
D
V
V
F
S
L
Y
H
T
K
Q
A
Site 42
Y552
G
D
V
V
F
S
L
Y
H
T
K
Q
A
P
R
Site 43
T554
V
V
F
S
L
Y
H
T
K
Q
A
P
R
L
G
Site 44
T567
L
G
A
R
E
P
G
T
R
A
S
G
Q
L
I
Site 45
S570
R
E
P
G
T
R
A
S
G
Q
L
I
D
K
G
Site 46
Y584
G
W
V
L
G
R
D
Y
S
R
V
E
A
P
L
Site 47
S585
W
V
L
G
R
D
Y
S
R
V
E
A
P
L
V
Site 48
S602
E
G
E
S
I
Q
G
S
H
V
T
R
W
P
G
Site 49
T605
S
I
Q
G
S
H
V
T
R
W
P
G
V
Y
L
Site 50
S619
L
L
Q
W
Q
M
H
S
P
P
S
S
V
A
C
Site 51
S622
W
Q
M
H
S
P
P
S
S
V
A
C
S
L
P
Site 52
S623
Q
M
H
S
P
P
S
S
V
A
C
S
L
P
G
Site 53
T636
P
G
V
D
D
V
L
T
A
L
H
S
P
G
P
Site 54
S640
D
V
L
T
A
L
H
S
P
G
P
K
C
K
L
Site 55
S662
A
S
E
D
F
R
G
S
M
S
S
L
E
S
C
Site 56
S664
E
D
F
R
G
S
M
S
S
L
E
S
C
T
S
Site 57
S665
D
F
R
G
S
M
S
S
L
E
S
C
T
S
G
Site 58
S668
G
S
M
S
S
L
E
S
C
T
S
G
F
S
Q
Site 59
S671
S
S
L
E
S
C
T
S
G
F
S
Q
L
S
A
Site 60
S677
T
S
G
F
S
Q
L
S
A
A
T
S
S
S
S
Site 61
T680
F
S
Q
L
S
A
A
T
S
S
S
S
S
G
Q
Site 62
S681
S
Q
L
S
A
A
T
S
S
S
S
S
G
Q
S
Site 63
S682
Q
L
S
A
A
T
S
S
S
S
S
G
Q
S
H
Site 64
S683
L
S
A
A
T
S
S
S
S
S
G
Q
S
H
S
Site 65
S684
S
A
A
T
S
S
S
S
S
G
Q
S
H
S
S
Site 66
S685
A
A
T
S
S
S
S
S
G
Q
S
H
S
S
S
Site 67
S688
S
S
S
S
S
G
Q
S
H
S
S
S
L
V
S
Site 68
S690
S
S
S
G
Q
S
H
S
S
S
L
V
S
R
_
Site 69
S691
S
S
G
Q
S
H
S
S
S
L
V
S
R
_
_
Site 70
S692
S
G
Q
S
H
S
S
S
L
V
S
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation