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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Septin-4
Full Name:
Septin-4
Alias:
ARTS; Bradeion beta; Bradeoin; Brain protein H5; CE5B3; Cell division control-related protein 2; Cerebral protein 7; H5; MART; Peanut-li; PNUTL2; Septin 4; Septin-M
Type:
Apoptosis protein
Mass (Da):
55098
Number AA:
478
UniProt ID:
O43236
International Prot ID:
IPI00011589
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0007049
GO:0000910
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
L
G
W
Q
G
N
S
V
P
E
D
R
T
E
Site 2
T17
N
S
V
P
E
D
R
T
E
A
G
I
K
R
F
Site 3
T28
I
K
R
F
L
E
D
T
T
D
D
G
E
L
S
Site 4
T29
K
R
F
L
E
D
T
T
D
D
G
E
L
S
K
Site 5
S35
T
T
D
D
G
E
L
S
K
F
V
K
D
F
S
Site 6
S42
S
K
F
V
K
D
F
S
G
N
A
S
C
H
P
Site 7
S46
K
D
F
S
G
N
A
S
C
H
P
P
E
A
K
Site 8
T54
C
H
P
P
E
A
K
T
W
A
S
R
P
Q
V
Site 9
S57
P
E
A
K
T
W
A
S
R
P
Q
V
P
E
P
Site 10
Y72
R
P
Q
A
P
D
L
Y
D
D
D
L
E
F
R
Site 11
S82
D
L
E
F
R
P
P
S
R
P
Q
S
S
D
N
Site 12
S86
R
P
P
S
R
P
Q
S
S
D
N
Q
Q
Y
F
Site 13
S87
P
P
S
R
P
Q
S
S
D
N
Q
Q
Y
F
C
Site 14
Y92
Q
S
S
D
N
Q
Q
Y
F
C
A
P
A
P
L
Site 15
S100
F
C
A
P
A
P
L
S
P
S
A
R
P
R
S
Site 16
S102
A
P
A
P
L
S
P
S
A
R
P
R
S
P
W
Site 17
S107
S
P
S
A
R
P
R
S
P
W
G
K
L
D
P
Site 18
Y115
P
W
G
K
L
D
P
Y
D
S
S
E
D
D
K
Site 19
S117
G
K
L
D
P
Y
D
S
S
E
D
D
K
E
Y
Site 20
S118
K
L
D
P
Y
D
S
S
E
D
D
K
E
Y
V
Site 21
Y124
S
S
E
D
D
K
E
Y
V
G
F
A
T
L
P
Site 22
T129
K
E
Y
V
G
F
A
T
L
P
N
Q
V
H
R
Site 23
S138
P
N
Q
V
H
R
K
S
V
K
K
G
F
D
F
Site 24
T167
L
V
N
S
L
F
L
T
D
L
Y
R
D
R
K
Site 25
Y170
S
L
F
L
T
D
L
Y
R
D
R
K
L
L
G
Site 26
Y236
I
D
Q
Q
F
E
Q
Y
F
R
D
E
S
G
L
Site 27
S241
E
Q
Y
F
R
D
E
S
G
L
N
R
K
N
I
Site 28
T293
P
I
L
A
K
A
D
T
L
T
P
P
E
V
D
Site 29
T295
L
A
K
A
D
T
L
T
P
P
E
V
D
H
K
Site 30
Y318
E
H
F
G
I
K
I
Y
Q
F
P
D
C
D
S
Site 31
S325
Y
Q
F
P
D
C
D
S
D
E
D
E
D
F
K
Site 32
Y365
R
R
V
R
G
R
L
Y
P
W
G
I
V
E
V
Site 33
T402
L
K
D
V
T
R
E
T
H
Y
E
N
Y
R
A
Site 34
Y404
D
V
T
R
E
T
H
Y
E
N
Y
R
A
Q
C
Site 35
T429
E
R
N
R
N
K
L
T
R
E
S
G
T
D
F
Site 36
S432
R
N
K
L
T
R
E
S
G
T
D
F
P
I
P
Site 37
T434
K
L
T
R
E
S
G
T
D
F
P
I
P
A
V
Site 38
T449
P
P
G
T
D
P
E
T
E
K
L
I
R
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation