PhosphoNET

           
Protein Info 
   
Short Name:  CRX
Full Name:  Cone-rod homeobox protein
Alias: 
Type: 
Mass (Da):  32261
Number AA:  299
UniProt ID:  O43186
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y11YMNPGPHYSVNALAL
Site 2S12MNPGPHYSVNALALS
Site 3Y32LMHQAVPYPSAPRKQ
Site 4S34HQAVPYPSAPRKQRR
Site 5T44RKQRRERTTFTRSQL
Site 6T45KQRRERTTFTRSQLE
Site 7S49ERTTFTRSQLEELEA
Site 8Y63ALFAKTQYPDVYARE
Site 9Y67KTQYPDVYAREEVAL
Site 10S81LKINLPESRVQVWFK
Site 11S124AKRKAGTSPRPSTDV
Site 12S128AGTSPRPSTDVCPDP
Site 13T129GTSPRPSTDVCPDPL
Site 14S139CPDPLGISDSYSPPL
Site 15S141DPLGISDSYSPPLPG
Site 16Y142PLGISDSYSPPLPGP
Site 17S143LGISDSYSPPLPGPS
Site 18S150SPPLPGPSGSPTTAV
Site 19S152PLPGPSGSPTTAVAT
Site 20T154PGPSGSPTTAVATVS
Site 21S167VSIWSPASESPLPEA
Site 22S169IWSPASESPLPEAQR
Site 23S188ASGPSLTSAPYAMTY
Site 24S203APASAFCSSPSAYGS
Site 25S204PASAFCSSPSAYGSP
Site 26S206SAFCSSPSAYGSPSS
Site 27Y208FCSSPSAYGSPSSYF
Site 28S210SSPSAYGSPSSYFSG
Site 29S212PSAYGSPSSYFSGLD
Site 30S213SAYGSPSSYFSGLDP
Site 31Y214AYGSPSSYFSGLDPY
Site 32S216GSPSSYFSGLDPYLS
Site 33Y221YFSGLDPYLSPMVPQ
Site 34S223SGLDPYLSPMVPQLG
Site 35S238GPALSPLSGPSVGPS
Site 36S245SGPSVGPSLAQSPTS
Site 37S249VGPSLAQSPTSLSGQ
Site 38T251PSLAQSPTSLSGQSY
Site 39S252SLAQSPTSLSGQSYG
Site 40S254AQSPTSLSGQSYGAY
Site 41Y258TSLSGQSYGAYSPVD
Site 42Y261SGQSYGAYSPVDSLE
Site 43S262GQSYGAYSPVDSLEF
Site 44S266GAYSPVDSLEFKDPT
Site 45T273SLEFKDPTGTWKFTY
Site 46Y280TGTWKFTYNPMDPLD
Site 47Y288NPMDPLDYKDQSAWK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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