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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP26A1
Full Name:
Cytochrome P450 26A1
Alias:
Cytochrome P450 retinoic acid-inactivating 1;Retinoic acid 4-hydroxylase;Retinoic acid-metabolizing cytochrome
Type:
Mass (Da):
56199
Number AA:
497
UniProt ID:
O43174
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y31
A
I
K
L
W
D
L
Y
C
V
S
G
R
D
R
Site 2
S39
C
V
S
G
R
D
R
S
C
A
L
P
L
P
P
Site 3
Y75
L
Q
M
K
R
R
K
Y
G
F
I
Y
K
T
H
Site 4
Y79
R
R
K
Y
G
F
I
Y
K
T
H
L
F
G
R
Site 5
T81
K
Y
G
F
I
Y
K
T
H
L
F
G
R
P
T
Site 6
T88
T
H
L
F
G
R
P
T
V
R
V
M
G
A
D
Site 7
S126
I
L
G
S
G
C
L
S
N
L
H
D
S
S
H
Site 8
S131
C
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
Site 9
S132
L
S
N
L
H
D
S
S
H
K
Q
R
K
K
V
Site 10
S145
K
V
I
M
R
A
F
S
R
E
A
L
E
C
Y
Site 11
Y152
S
R
E
A
L
E
C
Y
V
P
V
I
T
E
E
Site 12
S163
I
T
E
E
V
G
S
S
L
E
Q
W
L
S
C
Site 13
S169
S
S
L
E
Q
W
L
S
C
G
E
R
G
L
L
Site 14
Y178
G
E
R
G
L
L
V
Y
P
E
V
K
R
L
M
Site 15
S206
Q
L
A
G
D
G
D
S
E
Q
Q
L
V
E
A
Site 16
S261
K
I
C
G
L
R
A
S
E
A
G
Q
G
C
K
Site 17
S278
L
Q
L
L
I
E
H
S
W
E
R
G
E
R
L
Site 18
T295
Q
A
L
K
Q
S
S
T
E
L
L
F
G
G
H
Site 19
S307
G
G
H
E
T
T
A
S
A
A
T
S
L
I
T
Site 20
S332
K
V
R
E
E
L
K
S
K
G
L
L
C
K
S
Site 21
S339
S
K
G
L
L
C
K
S
N
Q
D
N
K
L
D
Site 22
T380
G
F
R
V
A
L
K
T
F
E
L
N
G
Y
Q
Site 23
Y386
K
T
F
E
L
N
G
Y
Q
I
P
K
G
W
N
Site 24
S428
L
P
H
P
E
D
A
S
R
F
S
F
I
P
F
Site 25
S431
P
E
D
A
S
R
F
S
F
I
P
F
G
G
G
Site 26
T473
Q
L
L
N
G
P
P
T
M
K
T
S
P
T
V
Site 27
T476
N
G
P
P
T
M
K
T
S
P
T
V
Y
P
V
Site 28
S477
G
P
P
T
M
K
T
S
P
T
V
Y
P
V
D
Site 29
T479
P
T
M
K
T
S
P
T
V
Y
P
V
D
N
L
Site 30
Y481
M
K
T
S
P
T
V
Y
P
V
D
N
L
P
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation