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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0406
Full Name:
TEL2-interacting protein 1 homolog
Alias:
K0406
Type:
Unknown function
Mass (Da):
122069
Number AA:
1089
UniProt ID:
O43156
International Prot ID:
IPI00011702
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
V
C
V
Q
L
T
K
T
Q
T
V
E
N
V
E
Site 2
T26
V
Q
L
T
K
T
Q
T
V
E
N
V
E
H
L
Site 3
T35
E
N
V
E
H
L
Q
T
R
L
Q
A
V
S
D
Site 4
S41
Q
T
R
L
Q
A
V
S
D
S
A
L
Q
E
L
Site 5
T62
P
L
R
F
T
L
K
T
P
G
P
K
R
E
R
Site 6
S73
K
R
E
R
L
I
Q
S
V
V
E
C
L
T
F
Site 7
S101
Q
E
L
F
S
E
L
S
A
C
L
Y
S
P
S
Site 8
Y105
S
E
L
S
A
C
L
Y
S
P
S
S
Q
K
P
Site 9
S106
E
L
S
A
C
L
Y
S
P
S
S
Q
K
P
A
Site 10
S108
S
A
C
L
Y
S
P
S
S
Q
K
P
A
A
V
Site 11
S109
A
C
L
Y
S
P
S
S
Q
K
P
A
A
V
S
Site 12
S167
G
L
A
E
Q
E
K
S
K
Q
I
K
I
A
A
Site 13
S193
D
C
Q
D
H
P
R
S
L
D
E
L
E
Q
K
Site 14
T222
T
A
L
T
R
L
I
T
G
D
F
K
Q
G
H
Site 15
S230
G
D
F
K
Q
G
H
S
I
V
V
S
S
L
K
Site 16
S256
D
E
Q
L
K
R
I
S
K
V
Q
A
K
P
A
Site 17
Y274
R
V
A
E
L
M
V
Y
R
E
A
D
W
V
K
Site 18
T283
E
A
D
W
V
K
K
T
G
D
K
L
T
I
L
Site 19
S344
V
G
L
V
N
D
E
S
P
E
I
Q
A
Q
C
Site 20
T383
E
S
L
H
S
L
A
T
S
L
P
R
L
M
N
Site 21
S384
S
L
H
S
L
A
T
S
L
P
R
L
M
N
S
Site 22
S391
S
L
P
R
L
M
N
S
Q
D
D
Q
G
K
F
Site 23
S399
Q
D
D
Q
G
K
F
S
T
L
S
L
L
L
G
Site 24
T400
D
D
Q
G
K
F
S
T
L
S
L
L
L
G
Y
Site 25
S453
V
E
E
R
R
W
N
S
D
D
L
N
A
S
P
Site 26
S459
N
S
D
D
L
N
A
S
P
K
T
S
A
T
Q
Site 27
T462
D
L
N
A
S
P
K
T
S
A
T
Q
P
W
N
Site 28
S463
L
N
A
S
P
K
T
S
A
T
Q
P
W
N
R
Site 29
Y475
W
N
R
I
Q
R
R
Y
F
R
F
F
T
D
E
Site 30
T480
R
R
Y
F
R
F
F
T
D
E
R
I
F
M
L
Site 31
Y512
V
D
H
F
M
E
L
Y
H
Q
S
V
V
Y
R
Site 32
T548
L
H
E
K
H
I
K
T
N
P
E
E
L
R
E
Site 33
S559
E
L
R
E
I
V
T
S
I
L
E
E
Y
T
S
Site 34
Y564
V
T
S
I
L
E
E
Y
T
S
Q
E
N
W
Y
Site 35
S566
S
I
L
E
E
Y
T
S
Q
E
N
W
Y
L
V
Site 36
Y571
Y
T
S
Q
E
N
W
Y
L
V
T
C
L
E
T
Site 37
S597
P
G
L
Q
A
I
T
S
G
E
H
T
C
Q
V
Site 38
S606
E
H
T
C
Q
V
T
S
F
L
A
F
S
K
P
Site 39
T616
A
F
S
K
P
S
P
T
I
C
S
M
N
S
N
Site 40
Y749
L
A
T
L
D
Q
F
Y
D
K
R
A
A
S
F
Site 41
T774
L
A
Q
W
F
P
D
T
G
N
L
G
H
L
Q
Site 42
S784
L
G
H
L
Q
E
Q
S
L
G
E
E
G
S
H
Site 43
S802
R
P
A
A
L
E
K
S
T
T
T
A
E
D
I
Site 44
T804
A
A
L
E
K
S
T
T
T
A
E
D
I
E
Q
Site 45
S828
D
V
A
D
G
N
V
S
D
F
D
N
E
E
E
Site 46
S838
D
N
E
E
E
E
Q
S
V
P
P
K
V
D
E
Site 47
S875
E
R
C
I
H
L
L
S
D
K
N
L
Q
I
R
Site 48
S913
L
A
H
Q
A
W
P
S
L
V
H
R
L
T
R
Site 49
T935
R
A
F
K
V
L
R
T
L
G
S
K
C
G
D
Site 50
S938
K
V
L
R
T
L
G
S
K
C
G
D
F
L
R
Site 51
S959
V
L
P
K
L
A
G
S
L
V
T
Q
A
P
I
Site 52
T962
K
L
A
G
S
L
V
T
Q
A
P
I
S
A
R
Site 53
S967
L
V
T
Q
A
P
I
S
A
R
A
G
P
V
Y
Site 54
Y974
S
A
R
A
G
P
V
Y
S
H
T
L
A
F
K
Site 55
S1029
K
L
Q
E
A
A
R
S
V
F
L
H
L
M
K
Site 56
S1041
L
M
K
V
D
P
D
S
T
W
F
L
L
N
E
Site 57
T1056
L
Y
C
P
V
Q
F
T
P
P
H
P
S
L
H
Site 58
S1061
Q
F
T
P
P
H
P
S
L
H
P
V
Q
L
H
Site 59
Y1077
A
S
G
Q
Q
N
P
Y
T
T
N
V
L
Q
L
Site 60
T1078
S
G
Q
Q
N
P
Y
T
T
N
V
L
Q
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation