KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
YY2
Full Name:
Transcription factor YY2
Alias:
Similar to jc2426 (pid:g1079317); Similar to jc2426 (pid;g1079317); Transcription activator/repressor protein delta/yy1; Transcription factor yin yang 2; Tyy2; Yy2; Yy2 transcription factor; Znf631
Type:
Intracellular, Nucleus protein
Mass (Da):
41347
Number AA:
372
UniProt ID:
O15391
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
L
P
M
E
D
I
P
T
E
S
V
Q
Y
E
D
Site 2
Y42
I
P
T
E
S
V
Q
Y
E
D
V
D
G
N
W
Site 3
Y51
D
V
D
G
N
W
I
Y
G
G
H
N
H
P
P
Site 4
Y90
T
Q
E
E
V
V
G
Y
C
D
S
D
N
Q
L
Site 5
S93
E
V
V
G
Y
C
D
S
D
N
Q
L
G
N
D
Site 6
S110
D
Q
L
A
L
P
D
S
I
E
D
E
H
F
Q
Site 7
T119
E
D
E
H
F
Q
M
T
L
A
S
L
S
A
S
Site 8
S129
S
L
S
A
S
A
A
S
T
S
T
S
T
Q
S
Site 9
T130
L
S
A
S
A
A
S
T
S
T
S
T
Q
S
R
Site 10
S131
S
A
S
A
A
S
T
S
T
S
T
Q
S
R
S
Site 11
S133
S
A
A
S
T
S
T
S
T
Q
S
R
S
K
K
Site 12
T134
A
A
S
T
S
T
S
T
Q
S
R
S
K
K
P
Site 13
S136
S
T
S
T
S
T
Q
S
R
S
K
K
P
S
K
Site 14
S138
S
T
S
T
Q
S
R
S
K
K
P
S
K
K
P
Site 15
S142
Q
S
R
S
K
K
P
S
K
K
P
S
G
K
S
Site 16
S146
K
K
P
S
K
K
P
S
G
K
S
A
T
S
T
Site 17
S149
S
K
K
P
S
G
K
S
A
T
S
T
E
A
N
Site 18
S152
P
S
G
K
S
A
T
S
T
E
A
N
P
A
G
Site 19
T153
S
G
K
S
A
T
S
T
E
A
N
P
A
G
S
Site 20
S160
T
E
A
N
P
A
G
S
S
S
S
L
G
T
R
Site 21
S161
E
A
N
P
A
G
S
S
S
S
L
G
T
R
K
Site 22
S162
A
N
P
A
G
S
S
S
S
L
G
T
R
K
W
Site 23
S163
N
P
A
G
S
S
S
S
L
G
T
R
K
W
E
Site 24
T178
Q
K
Q
M
Q
V
K
T
L
E
G
E
F
S
V
Site 25
S184
K
T
L
E
G
E
F
S
V
T
M
W
S
P
N
Site 26
T186
L
E
G
E
F
S
V
T
M
W
S
P
N
D
N
Site 27
Y210
Q
A
E
N
P
P
D
Y
S
E
Y
L
K
G
K
Site 28
S211
A
E
N
P
P
D
Y
S
E
Y
L
K
G
K
K
Site 29
Y213
N
P
P
D
Y
S
E
Y
L
K
G
K
K
L
P
Site 30
S230
G
L
P
G
I
D
L
S
D
P
K
Q
L
A
E
Site 31
T253
S
K
G
E
P
P
K
T
V
P
C
S
Y
S
G
Site 32
S257
P
P
K
T
V
P
C
S
Y
S
G
C
E
K
M
Site 33
Y268
C
E
K
M
F
R
D
Y
A
A
M
R
K
H
L
Site 34
S295
C
G
K
A
F
L
E
S
S
K
L
R
R
H
Q
Site 35
S296
G
K
A
F
L
E
S
S
K
L
R
R
H
Q
L
Site 36
T306
R
R
H
Q
L
V
H
T
G
E
K
P
F
Q
C
Site 37
T314
G
E
K
P
F
Q
C
T
F
E
G
C
G
K
R
Site 38
S323
E
G
C
G
K
R
F
S
L
D
F
N
L
R
T
Site 39
T330
S
L
D
F
N
L
R
T
H
L
R
I
H
T
G
Site 40
T336
R
T
H
L
R
I
H
T
G
D
K
P
F
V
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation