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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OGT
Full Name:
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Alias:
EC 2.4.1.-; O-GlcNAc transferase p110; O-GlcNAc transferase subunit p110; OGT1; O-linked N-acetylglucosamine transferase 110 kDa subunit; UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa
Type:
Transferase; EC 2.4.1.-; Glycan Metabolism - O-glycan biosynthesis
Mass (Da):
116925
Number AA:
1046
UniProt ID:
O15294
International Prot ID:
IPI00607723
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070688
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0008375
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006493
GO:0007584
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
S
V
G
N
V
A
D
Site 2
S4
_
_
_
_
M
A
S
S
V
G
N
V
A
D
S
Site 3
S11
S
V
G
N
V
A
D
S
T
E
P
T
K
R
M
Site 4
T12
V
G
N
V
A
D
S
T
E
P
T
K
R
M
L
Site 5
T15
V
A
D
S
T
E
P
T
K
R
M
L
S
F
Q
Site 6
S20
E
P
T
K
R
M
L
S
F
Q
G
L
A
E
L
Site 7
Y32
A
E
L
A
H
R
E
Y
Q
A
G
D
F
E
A
Site 8
T55
W
R
Q
E
P
D
N
T
G
V
L
L
L
L
S
Site 9
S74
Q
C
R
R
L
D
R
S
A
H
F
S
T
L
A
Site 10
S78
L
D
R
S
A
H
F
S
T
L
A
I
K
Q
N
Site 11
S93
P
L
L
A
E
A
Y
S
N
L
G
N
V
Y
K
Site 12
Y157
L
Q
Y
N
P
D
L
Y
C
V
R
S
D
L
G
Site 13
S161
P
D
L
Y
C
V
R
S
D
L
G
N
L
L
K
Site 14
T219
H
H
F
E
K
A
V
T
L
D
P
N
F
L
D
Site 15
Y269
H
G
N
L
A
C
V
Y
Y
E
Q
G
L
I
D
Site 16
Y282
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
Site 17
Y296
Q
P
H
F
P
D
A
Y
C
N
L
A
N
A
L
Site 18
S308
N
A
L
K
E
K
G
S
V
A
E
A
E
D
C
Site 19
T325
T
A
L
R
L
C
P
T
H
A
D
S
L
N
N
Site 20
S369
A
A
H
S
N
L
A
S
V
L
Q
Q
Q
G
K
Site 21
S391
Y
K
E
A
I
R
I
S
P
T
F
A
D
A
Y
Site 22
T393
E
A
I
R
I
S
P
T
F
A
D
A
Y
S
N
Site 23
Y398
S
P
T
F
A
D
A
Y
S
N
M
G
N
T
L
Site 24
S399
P
T
F
A
D
A
Y
S
N
M
G
N
T
L
K
Site 25
S433
P
A
F
A
D
A
H
S
N
L
A
S
I
H
K
Site 26
S437
D
A
H
S
N
L
A
S
I
H
K
D
S
G
N
Site 27
Y466
K
P
D
F
P
D
A
Y
C
N
L
A
H
C
L
Site 28
Y482
I
V
C
D
W
T
D
Y
D
E
R
M
K
K
L
Site 29
S504
L
E
K
N
R
L
P
S
V
H
P
H
H
S
M
Site 30
S510
P
S
V
H
P
H
H
S
M
L
Y
P
L
S
H
Site 31
Y513
H
P
H
H
S
M
L
Y
P
L
S
H
G
F
R
Site 32
S516
H
S
M
L
Y
P
L
S
H
G
F
R
K
A
I
Site 33
Y543
N
V
L
H
K
P
P
Y
E
H
P
K
D
L
K
Site 34
S552
H
P
K
D
L
K
L
S
D
G
R
L
R
V
G
Site 35
Y560
D
G
R
L
R
V
G
Y
V
S
S
D
F
G
N
Site 36
S562
R
L
R
V
G
Y
V
S
S
D
F
G
N
H
P
Site 37
S563
L
R
V
G
Y
V
S
S
D
F
G
N
H
P
T
Site 38
S576
P
T
S
H
L
M
Q
S
I
P
G
M
H
N
P
Site 39
Y591
D
K
F
E
V
F
C
Y
A
L
S
P
D
D
G
Site 40
S594
E
V
F
C
Y
A
L
S
P
D
D
G
T
N
F
Site 41
T599
A
L
S
P
D
D
G
T
N
F
R
V
K
V
M
Site 42
S684
I
I
T
D
Q
E
T
S
P
A
E
V
A
E
Q
Site 43
Y698
Q
Y
S
E
K
L
A
Y
M
P
H
T
F
F
I
Site 44
Y730
F
K
S
N
G
H
I
Y
D
N
R
I
V
L
N
Site 45
S767
D
G
G
D
N
A
D
S
S
N
T
A
L
N
M
Site 46
S768
G
G
D
N
A
D
S
S
N
T
A
L
N
M
P
Site 47
T798
N
R
G
Q
I
Q
I
T
I
N
G
F
S
I
S
Site 48
T826
T
G
E
E
V
P
R
T
I
I
V
T
T
R
S
Site 49
S833
T
I
I
V
T
T
R
S
Q
Y
G
L
P
E
D
Site 50
Y835
I
V
T
T
R
S
Q
Y
G
L
P
E
D
A
I
Site 51
Y844
L
P
E
D
A
I
V
Y
C
N
F
N
Q
L
Y
Site 52
Y851
Y
C
N
F
N
Q
L
Y
K
I
D
P
S
T
L
Site 53
Y889
G
E
P
N
I
Q
Q
Y
A
Q
N
M
G
L
P
Site 54
S903
P
Q
N
R
I
I
F
S
P
V
A
P
K
E
E
Site 55
Y976
I
A
K
N
R
Q
E
Y
E
D
I
A
V
K
L
Site 56
Y989
K
L
G
T
D
L
E
Y
L
K
K
V
R
G
K
Site 57
S1003
K
V
W
K
Q
R
I
S
S
P
L
F
N
T
K
Site 58
S1004
V
W
K
Q
R
I
S
S
P
L
F
N
T
K
Q
Site 59
Y1020
T
M
E
L
E
R
L
Y
L
Q
M
W
E
H
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation