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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CLIC2
Full Name:
Chloride intracellular channel protein 2
Alias:
chloride intracellular channel 2; CLIC2b; XAP121
Type:
Membrane protein, integral; Channel, chloride
Mass (Da):
28360
Number AA:
247
UniProt ID:
O15247
International Prot ID:
IPI00221328
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034707
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0031404
GO:0005247
GO:0015035
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007165
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
S
G
L
R
P
G
T
Q
V
D
P
E
I
E
Site 2
S22
E
L
F
V
K
A
G
S
D
G
E
S
I
G
N
Site 3
S26
K
A
G
S
D
G
E
S
I
G
N
C
P
F
C
Site 4
T55
N
V
T
T
V
D
M
T
R
K
P
E
E
L
K
Site 5
T93
I
E
E
F
L
E
Q
T
L
A
P
P
R
Y
P
Site 6
Y99
Q
T
L
A
P
P
R
Y
P
H
L
S
P
K
Y
Site 7
Y106
Y
P
H
L
S
P
K
Y
K
E
S
F
D
V
G
Site 8
S109
L
S
P
K
Y
K
E
S
F
D
V
G
C
N
L
Site 9
S138
A
N
K
N
F
E
K
S
L
L
K
E
F
K
R
Site 10
Y149
E
F
K
R
L
D
D
Y
L
N
T
P
L
L
D
Site 11
T152
R
L
D
D
Y
L
N
T
P
L
L
D
E
I
D
Site 12
S162
L
D
E
I
D
P
D
S
A
E
E
P
P
V
S
Site 13
S169
S
A
E
E
P
P
V
S
R
R
L
F
L
D
G
Site 14
Y215
E
F
S
G
V
W
R
Y
L
H
N
A
Y
A
R
Site 15
Y220
W
R
Y
L
H
N
A
Y
A
R
E
E
F
T
H
Site 16
T228
A
R
E
E
F
T
H
T
C
P
E
D
K
E
I
Site 17
T238
E
D
K
E
I
E
N
T
Y
A
N
V
A
K
Q
Site 18
Y239
D
K
E
I
E
N
T
Y
A
N
V
A
K
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation