KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF185
Full Name:
Zinc finger protein 185
Alias:
LIM domain protein ZNF185; P1-A; Zinc finger protein 185 (lim domain)
Type:
DNA binding protein
Mass (Da):
49187
Number AA:
457
UniProt ID:
O15231
International Prot ID:
IPI00005688
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
D
Y
K
K
L
A
P
Y
N
I
R
R
S
S
T
Site 2
S17
A
P
Y
N
I
R
R
S
S
T
S
G
D
T
E
Site 3
S18
P
Y
N
I
R
R
S
S
T
S
G
D
T
E
E
Site 4
T19
Y
N
I
R
R
S
S
T
S
G
D
T
E
E
E
Site 5
S20
N
I
R
R
S
S
T
S
G
D
T
E
E
E
E
Site 6
S35
E
E
E
V
V
P
F
S
S
D
E
Q
K
R
R
Site 7
S36
E
E
V
V
P
F
S
S
D
E
Q
K
R
R
S
Site 8
S43
S
D
E
Q
K
R
R
S
E
A
A
S
G
V
L
Site 9
S47
K
R
R
S
E
A
A
S
G
V
L
R
R
T
A
Site 10
T53
A
S
G
V
L
R
R
T
A
P
R
E
H
S
Y
Site 11
S59
R
T
A
P
R
E
H
S
Y
V
L
S
A
A
K
Site 12
Y60
T
A
P
R
E
H
S
Y
V
L
S
A
A
K
K
Site 13
S63
R
E
H
S
Y
V
L
S
A
A
K
K
S
T
G
Site 14
S71
A
A
K
K
S
T
G
S
P
T
Q
E
T
Q
A
Site 15
T76
T
G
S
P
T
Q
E
T
Q
A
P
F
I
A
K
Site 16
S94
V
V
E
E
D
G
P
S
E
K
S
Q
D
P
P
Site 17
S97
E
D
G
P
S
E
K
S
Q
D
P
P
A
L
A
Site 18
T107
P
P
A
L
A
R
S
T
P
G
S
N
S
S
R
Site 19
S110
L
A
R
S
T
P
G
S
N
S
S
R
G
E
E
Site 20
S112
R
S
T
P
G
S
N
S
S
R
G
E
E
I
V
Site 21
S141
A
P
D
V
E
G
M
S
S
S
A
T
S
V
S
Site 22
S142
P
D
V
E
G
M
S
S
S
A
T
S
V
S
A
Site 23
S148
S
S
S
A
T
S
V
S
A
V
P
A
D
R
K
Site 24
S156
A
V
P
A
D
R
K
S
N
S
T
A
A
Q
E
Site 25
T159
A
D
R
K
S
N
S
T
A
A
Q
E
D
A
K
Site 26
Y176
P
K
G
A
L
A
D
Y
E
G
K
D
V
A
T
Site 27
S214
A
Q
Q
P
A
D
P
S
T
P
E
R
Q
S
S
Site 28
T215
Q
Q
P
A
D
P
S
T
P
E
R
Q
S
S
P
Site 29
S220
P
S
T
P
E
R
Q
S
S
P
S
G
S
E
Q
Site 30
S221
S
T
P
E
R
Q
S
S
P
S
G
S
E
Q
L
Site 31
S223
P
E
R
Q
S
S
P
S
G
S
E
Q
L
V
R
Site 32
S225
R
Q
S
S
P
S
G
S
E
Q
L
V
R
R
E
Site 33
S233
E
Q
L
V
R
R
E
S
C
G
S
S
V
L
T
Site 34
S236
V
R
R
E
S
C
G
S
S
V
L
T
D
F
E
Site 35
S237
R
R
E
S
C
G
S
S
V
L
T
D
F
E
G
Site 36
T240
S
C
G
S
S
V
L
T
D
F
E
G
K
D
V
Site 37
T273
Q
G
D
P
A
V
P
T
Q
Q
P
A
D
P
S
Site 38
S280
T
Q
Q
P
A
D
P
S
T
P
E
Q
Q
N
S
Site 39
T281
Q
Q
P
A
D
P
S
T
P
E
Q
Q
N
S
P
Site 40
S287
S
T
P
E
Q
Q
N
S
P
S
G
S
E
Q
F
Site 41
S289
P
E
Q
Q
N
S
P
S
G
S
E
Q
F
V
R
Site 42
S291
Q
Q
N
S
P
S
G
S
E
Q
F
V
R
R
E
Site 43
S299
E
Q
F
V
R
R
E
S
C
T
S
R
V
R
S
Site 44
T301
F
V
R
R
E
S
C
T
S
R
V
R
S
P
S
Site 45
S302
V
R
R
E
S
C
T
S
R
V
R
S
P
S
S
Site 46
S306
S
C
T
S
R
V
R
S
P
S
S
C
M
V
T
Site 47
S308
T
S
R
V
R
S
P
S
S
C
M
V
T
V
T
Site 48
S332
I
Y
I
P
A
P
A
S
E
L
D
S
S
S
T
Site 49
S336
A
P
A
S
E
L
D
S
S
S
T
T
K
G
I
Site 50
S337
P
A
S
E
L
D
S
S
S
T
T
K
G
I
L
Site 51
S338
A
S
E
L
D
S
S
S
T
T
K
G
I
L
F
Site 52
T339
S
E
L
D
S
S
S
T
T
K
G
I
L
F
V
Site 53
Y349
G
I
L
F
V
K
E
Y
V
N
A
S
E
V
S
Site 54
S353
V
K
E
Y
V
N
A
S
E
V
S
S
G
K
P
Site 55
S357
V
N
A
S
E
V
S
S
G
K
P
V
S
A
R
Site 56
S362
V
S
S
G
K
P
V
S
A
R
Y
S
N
V
S
Site 57
Y365
G
K
P
V
S
A
R
Y
S
N
V
S
S
I
E
Site 58
S366
K
P
V
S
A
R
Y
S
N
V
S
S
I
E
D
Site 59
S369
S
A
R
Y
S
N
V
S
S
I
E
D
S
F
A
Site 60
S370
A
R
Y
S
N
V
S
S
I
E
D
S
F
A
M
Site 61
S374
N
V
S
S
I
E
D
S
F
A
M
E
K
K
P
Site 62
S385
E
K
K
P
P
C
G
S
T
P
Y
S
E
R
T
Site 63
T386
K
K
P
P
C
G
S
T
P
Y
S
E
R
T
T
Site 64
Y388
P
P
C
G
S
T
P
Y
S
E
R
T
T
G
G
Site 65
S389
P
C
G
S
T
P
Y
S
E
R
T
T
G
G
I
Site 66
T393
T
P
Y
S
E
R
T
T
G
G
I
C
T
Y
C
Site 67
Y399
T
T
G
G
I
C
T
Y
C
N
R
E
I
R
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation