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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0355
Full Name:
Uncharacterized protein KIAA0355
Alias:
K0355; LOC9710
Type:
Unknown function
Mass (Da):
116020
Number AA:
1070
UniProt ID:
O15063
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
A
Q
D
S
K
M
D
Y
K
R
R
F
L
L
G
Site 2
Y32
K
V
Q
Q
H
Q
Q
Y
P
M
P
E
L
G
R
Site 3
S62
G
S
L
T
A
A
G
S
C
H
H
A
M
P
H
Site 4
S102
T
F
L
T
D
L
F
S
T
V
F
R
N
S
H
Site 5
T103
F
L
T
D
L
F
S
T
V
F
R
N
S
H
Y
Site 6
S108
F
S
T
V
F
R
N
S
H
Y
S
K
A
A
T
Site 7
S111
V
F
R
N
S
H
Y
S
K
A
A
T
Q
L
K
Site 8
T115
S
H
Y
S
K
A
A
T
Q
L
K
D
V
Q
E
Site 9
T132
M
E
A
A
S
R
L
T
S
A
I
K
P
E
I
Site 10
S133
E
A
A
S
R
L
T
S
A
I
K
P
E
I
A
Site 11
S160
F
T
D
Q
K
E
F
S
L
Q
D
I
E
V
L
Site 12
S208
I
V
P
E
K
K
N
S
G
S
G
G
G
L
S
Site 13
S210
P
E
K
K
N
S
G
S
G
G
G
L
S
G
M
Site 14
S215
S
G
S
G
G
G
L
S
G
M
G
H
T
P
E
Site 15
T220
G
L
S
G
M
G
H
T
P
E
V
E
E
A
V
Site 16
S229
E
V
E
E
A
V
R
S
W
R
G
A
A
E
A
Site 17
S238
R
G
A
A
E
A
T
S
R
L
R
E
R
G
C
Site 18
S260
E
V
Q
Q
L
F
C
S
Q
S
A
A
I
P
E
Site 19
S262
Q
Q
L
F
C
S
Q
S
A
A
I
P
E
H
Q
Site 20
Y296
E
S
L
G
H
C
E
Y
A
M
K
A
G
F
H
Site 21
T325
S
E
A
E
A
Q
Q
T
G
R
R
Q
T
P
P
Site 22
T330
Q
Q
T
G
R
R
Q
T
P
P
Q
P
M
Q
C
Site 23
S355
S
H
F
L
K
G
V
S
F
N
E
S
A
A
D
Site 24
S359
K
G
V
S
F
N
E
S
A
A
D
N
L
K
L
Site 25
Y381
L
M
K
E
A
G
C
Y
N
G
I
T
S
R
D
Site 26
T393
S
R
D
D
F
P
V
T
E
V
L
N
Q
V
C
Site 27
S440
E
A
Y
A
P
Q
I
S
L
E
G
S
R
I
V
Site 28
T462
C
L
K
E
D
P
A
T
M
S
L
L
Q
R
S
Site 29
S464
K
E
D
P
A
T
M
S
L
L
Q
R
S
L
D
Site 30
S469
T
M
S
L
L
Q
R
S
L
D
P
E
K
T
L
Site 31
T475
R
S
L
D
P
E
K
T
L
G
L
V
D
V
L
Site 32
S522
G
N
Q
A
D
L
P
S
G
N
G
N
K
S
S
Site 33
S528
P
S
G
N
G
N
K
S
S
G
G
L
Q
K
T
Site 34
S529
S
G
N
G
N
K
S
S
G
G
L
Q
K
T
F
Site 35
T535
S
S
G
G
L
Q
K
T
F
S
K
L
T
S
R
Site 36
S537
G
G
L
Q
K
T
F
S
K
L
T
S
R
F
T
Site 37
S541
K
T
F
S
K
L
T
S
R
F
T
K
K
A
S
Site 38
T544
S
K
L
T
S
R
F
T
K
K
A
S
C
T
S
Site 39
S548
S
R
F
T
K
K
A
S
C
T
S
S
S
S
S
Site 40
T550
F
T
K
K
A
S
C
T
S
S
S
S
S
T
N
Site 41
S551
T
K
K
A
S
C
T
S
S
S
S
S
T
N
Y
Site 42
S552
K
K
A
S
C
T
S
S
S
S
S
T
N
Y
S
Site 43
S553
K
A
S
C
T
S
S
S
S
S
T
N
Y
S
I
Site 44
S554
A
S
C
T
S
S
S
S
S
T
N
Y
S
I
Q
Site 45
S555
S
C
T
S
S
S
S
S
T
N
Y
S
I
Q
N
Site 46
T556
C
T
S
S
S
S
S
T
N
Y
S
I
Q
N
T
Site 47
S559
S
S
S
S
T
N
Y
S
I
Q
N
T
P
S
K
Site 48
T563
T
N
Y
S
I
Q
N
T
P
S
K
N
I
F
I
Site 49
T586
K
M
P
G
N
I
D
T
R
L
Q
S
I
L
N
Site 50
S590
N
I
D
T
R
L
Q
S
I
L
N
I
G
N
F
Site 51
T600
N
I
G
N
F
P
R
T
T
D
P
S
Q
S
A
Site 52
T601
I
G
N
F
P
R
T
T
D
P
S
Q
S
A
Q
Site 53
S604
F
P
R
T
T
D
P
S
Q
S
A
Q
N
S
S
Site 54
S606
R
T
T
D
P
S
Q
S
A
Q
N
S
S
N
T
Site 55
S610
P
S
Q
S
A
Q
N
S
S
N
T
V
A
N
G
Site 56
T613
S
A
Q
N
S
S
N
T
V
A
N
G
F
L
M
Site 57
S654
Q
E
V
I
D
F
L
S
G
F
N
M
G
Q
S
Site 58
S661
S
G
F
N
M
G
Q
S
H
Q
G
S
P
L
V
Site 59
S665
M
G
Q
S
H
Q
G
S
P
L
V
T
R
H
N
Site 60
T669
H
Q
G
S
P
L
V
T
R
H
N
S
A
A
T
Site 61
S673
P
L
V
T
R
H
N
S
A
A
T
A
M
V
T
Site 62
S693
A
M
Q
P
Q
Q
P
S
L
P
V
P
P
P
P
Site 63
T709
A
P
Q
A
G
A
H
T
P
L
T
P
Q
P
G
Site 64
T712
A
G
A
H
T
P
L
T
P
Q
P
G
L
A
P
Site 65
S723
G
L
A
P
Q
Q
Q
S
P
K
Q
Q
Q
P
Q
Site 66
S761
G
K
W
V
H
G
S
S
Q
Q
P
A
Q
A
V
Site 67
S782
L
G
Q
W
P
G
I
S
D
L
S
S
D
L
Y
Site 68
S785
W
P
G
I
S
D
L
S
S
D
L
Y
S
L
G
Site 69
T817
P
Q
G
P
R
N
N
T
W
P
N
R
D
Q
S
Site 70
S824
T
W
P
N
R
D
Q
S
D
G
V
F
G
M
L
Site 71
S843
P
F
D
P
A
V
G
S
D
P
E
F
A
R
Y
Site 72
Y850
S
D
P
E
F
A
R
Y
V
A
G
V
S
Q
A
Site 73
S855
A
R
Y
V
A
G
V
S
Q
A
M
Q
Q
K
R
Site 74
S904
D
G
L
H
G
G
W
S
G
A
Q
G
D
S
A
Site 75
S910
W
S
G
A
Q
G
D
S
A
S
S
S
D
E
T
Site 76
S912
G
A
Q
G
D
S
A
S
S
S
D
E
T
S
S
Site 77
S913
A
Q
G
D
S
A
S
S
S
D
E
T
S
S
A
Site 78
S914
Q
G
D
S
A
S
S
S
D
E
T
S
S
A
N
Site 79
T917
S
A
S
S
S
D
E
T
S
S
A
N
G
D
S
Site 80
S918
A
S
S
S
D
E
T
S
S
A
N
G
D
S
L
Site 81
S919
S
S
S
D
E
T
S
S
A
N
G
D
S
L
F
Site 82
S924
T
S
S
A
N
G
D
S
L
F
S
M
F
S
G
Site 83
S945
V
K
Q
R
R
K
H
S
S
G
E
Q
D
T
S
Site 84
S946
K
Q
R
R
K
H
S
S
G
E
Q
D
T
S
T
Site 85
S952
S
S
G
E
Q
D
T
S
T
L
P
S
P
P
L
Site 86
T953
S
G
E
Q
D
T
S
T
L
P
S
P
P
L
L
Site 87
S956
Q
D
T
S
T
L
P
S
P
P
L
L
T
T
V
Site 88
T961
L
P
S
P
P
L
L
T
T
V
E
D
V
N
Q
Site 89
T962
P
S
P
P
L
L
T
T
V
E
D
V
N
Q
D
Site 90
T972
D
V
N
Q
D
N
K
T
K
T
W
P
P
K
A
Site 91
T974
N
Q
D
N
K
T
K
T
W
P
P
K
A
P
W
Site 92
S985
K
A
P
W
Q
H
P
S
P
L
P
S
T
L
P
Site 93
S989
Q
H
P
S
P
L
P
S
T
L
P
S
P
S
A
Site 94
T990
H
P
S
P
L
P
S
T
L
P
S
P
S
A
P
Site 95
S993
P
L
P
S
T
L
P
S
P
S
A
P
L
Y
A
Site 96
Y999
P
S
P
S
A
P
L
Y
A
V
T
S
P
G
S
Site 97
T1002
S
A
P
L
Y
A
V
T
S
P
G
S
Q
W
N
Site 98
Y1033
C
S
A
A
A
F
S
Y
V
Q
T
P
P
Q
P
Site 99
T1036
A
A
F
S
Y
V
Q
T
P
P
Q
P
P
P
P
Site 100
Y1066
K
G
E
R
R
P
A
Y
L
P
Q
Y
_
_
_
Site 101
Y1070
R
P
A
Y
L
P
Q
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation