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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB5
Full Name:
Zinc finger and BTB domain-containing protein 5
Alias:
KIAA0354; zinc finger and BTB domain containing 5; zinc finger and BTB domain containing protein 5
Type:
Unknown function
Mass (Da):
74278
Number AA:
677
UniProt ID:
O15062
International Prot ID:
IPI00006671
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
Q
I
F
Q
Q
L
N
Y
Q
R
L
H
G
Q
L
Site 2
T61
S
V
A
E
G
D
Q
T
M
N
M
I
Q
L
D
Site 3
S110
A
S
H
L
H
L
N
S
V
V
K
A
C
K
H
Site 4
Y118
V
V
K
A
C
K
H
Y
L
T
T
R
T
L
P
Site 5
T120
K
A
C
K
H
Y
L
T
T
R
T
L
P
M
S
Site 6
T123
K
H
Y
L
T
T
R
T
L
P
M
S
P
P
S
Site 7
S127
T
T
R
T
L
P
M
S
P
P
S
E
R
V
Q
Site 8
S130
T
L
P
M
S
P
P
S
E
R
V
Q
E
Q
S
Site 9
S137
S
E
R
V
Q
E
Q
S
A
R
M
Q
R
S
F
Site 10
S143
Q
S
A
R
M
Q
R
S
F
M
L
Q
Q
L
G
Site 11
S160
I
V
S
S
A
L
N
S
S
Q
N
G
E
E
Q
Site 12
S161
V
S
S
A
L
N
S
S
Q
N
G
E
E
Q
P
Site 13
S172
E
E
Q
P
A
P
M
S
S
S
M
R
S
N
L
Site 14
S173
E
Q
P
A
P
M
S
S
S
M
R
S
N
L
D
Site 15
S174
Q
P
A
P
M
S
S
S
M
R
S
N
L
D
Q
Site 16
S177
P
M
S
S
S
M
R
S
N
L
D
Q
R
T
P
Site 17
T183
R
S
N
L
D
Q
R
T
P
F
P
M
R
R
L
Site 18
S196
R
L
H
K
R
K
Q
S
A
E
E
R
A
R
Q
Site 19
S208
A
R
Q
R
L
R
P
S
I
D
E
S
A
I
S
Site 20
S212
L
R
P
S
I
D
E
S
A
I
S
D
V
T
P
Site 21
S215
S
I
D
E
S
A
I
S
D
V
T
P
E
N
G
Site 22
T218
E
S
A
I
S
D
V
T
P
E
N
G
P
S
G
Site 23
S224
V
T
P
E
N
G
P
S
G
V
H
S
R
E
E
Site 24
S228
N
G
P
S
G
V
H
S
R
E
E
F
F
S
P
Site 25
S234
H
S
R
E
E
F
F
S
P
D
S
L
K
I
V
Site 26
S237
E
E
F
F
S
P
D
S
L
K
I
V
D
N
P
Site 27
S263
S
A
I
M
F
D
Q
S
F
G
T
Q
E
D
A
Site 28
S274
Q
E
D
A
Q
V
P
S
Q
S
D
N
S
A
G
Site 29
S276
D
A
Q
V
P
S
Q
S
D
N
S
A
G
N
M
Site 30
S287
A
G
N
M
A
Q
L
S
M
A
S
R
A
T
Q
Site 31
T293
L
S
M
A
S
R
A
T
Q
V
E
T
S
F
D
Site 32
S298
R
A
T
Q
V
E
T
S
F
D
Q
E
A
A
P
Site 33
S309
E
A
A
P
E
K
S
S
F
Q
C
E
N
P
E
Site 34
S331
H
M
R
V
V
V
K
S
E
P
L
S
S
P
E
Site 35
S335
V
V
K
S
E
P
L
S
S
P
E
P
Q
D
E
Site 36
S336
V
K
S
E
P
L
S
S
P
E
P
Q
D
E
V
Site 37
S344
P
E
P
Q
D
E
V
S
D
V
T
S
Q
A
E
Site 38
S348
D
E
V
S
D
V
T
S
Q
A
E
G
S
E
S
Site 39
S353
V
T
S
Q
A
E
G
S
E
S
V
E
V
E
G
Site 40
S355
S
Q
A
E
G
S
E
S
V
E
V
E
G
V
V
Site 41
S371
S
A
E
K
I
D
L
S
P
E
S
S
D
R
S
Site 42
S374
K
I
D
L
S
P
E
S
S
D
R
S
F
S
D
Site 43
S375
I
D
L
S
P
E
S
S
D
R
S
F
S
D
P
Site 44
S378
S
P
E
S
S
D
R
S
F
S
D
P
Q
S
S
Site 45
S380
E
S
S
D
R
S
F
S
D
P
Q
S
S
T
D
Site 46
S384
R
S
F
S
D
P
Q
S
S
T
D
R
V
G
D
Site 47
S385
S
F
S
D
P
Q
S
S
T
D
R
V
G
D
I
Site 48
T386
F
S
D
P
Q
S
S
T
D
R
V
G
D
I
H
Site 49
S405
T
N
N
L
E
H
K
S
T
F
S
I
S
N
F
Site 50
T406
N
N
L
E
H
K
S
T
F
S
I
S
N
F
L
Site 51
S408
L
E
H
K
S
T
F
S
I
S
N
F
L
N
K
Site 52
T422
K
S
R
G
N
N
F
T
A
N
Q
N
N
D
D
Site 53
T434
N
D
D
N
I
P
N
T
T
S
D
C
R
L
E
Site 54
S436
D
N
I
P
N
T
T
S
D
C
R
L
E
S
E
Site 55
S442
T
S
D
C
R
L
E
S
E
A
P
Y
L
L
S
Site 56
Y446
R
L
E
S
E
A
P
Y
L
L
S
P
E
A
G
Site 57
S449
S
E
A
P
Y
L
L
S
P
E
A
G
P
A
G
Site 58
S459
A
G
P
A
G
G
P
S
S
A
P
G
S
H
V
Site 59
S460
G
P
A
G
G
P
S
S
A
P
G
S
H
V
E
Site 60
S464
G
P
S
S
A
P
G
S
H
V
E
N
P
F
S
Site 61
S471
S
H
V
E
N
P
F
S
E
P
A
D
S
H
F
Site 62
S476
P
F
S
E
P
A
D
S
H
F
V
R
P
M
Q
Site 63
S494
G
L
P
C
V
Q
T
S
G
Y
Q
G
G
E
Q
Site 64
Y496
P
C
V
Q
T
S
G
Y
Q
G
G
E
Q
F
G
Site 65
S507
E
Q
F
G
M
D
F
S
R
S
G
L
G
L
H
Site 66
S509
F
G
M
D
F
S
R
S
G
L
G
L
H
S
S
Site 67
S524
F
S
R
V
M
I
G
S
P
R
G
G
A
S
N
Site 68
S530
G
S
P
R
G
G
A
S
N
F
P
Y
Y
R
R
Site 69
Y534
G
G
A
S
N
F
P
Y
Y
R
R
I
A
P
K
Site 70
Y535
G
A
S
N
F
P
Y
Y
R
R
I
A
P
K
M
Site 71
T546
A
P
K
M
P
V
V
T
S
V
R
S
S
Q
I
Site 72
S547
P
K
M
P
V
V
T
S
V
R
S
S
Q
I
P
Site 73
S551
V
V
T
S
V
R
S
S
Q
I
P
E
N
S
T
Site 74
S557
S
S
Q
I
P
E
N
S
T
S
S
Q
L
M
M
Site 75
S559
Q
I
P
E
N
S
T
S
S
Q
L
M
M
N
G
Site 76
S570
M
M
N
G
A
T
S
S
F
E
N
G
H
P
S
Site 77
S577
S
F
E
N
G
H
P
S
Q
P
G
P
P
Q
L
Site 78
S588
P
P
Q
L
T
R
A
S
A
D
V
L
S
K
C
Site 79
S593
R
A
S
A
D
V
L
S
K
C
K
K
A
L
S
Site 80
S600
S
K
C
K
K
A
L
S
E
H
N
V
L
V
V
Site 81
T626
C
K
T
F
L
T
L
T
D
C
K
K
H
I
R
Site 82
T636
K
K
H
I
R
V
H
T
G
E
K
P
Y
A
C
Site 83
Y641
V
H
T
G
E
K
P
Y
A
C
L
K
C
G
K
Site 84
S651
L
K
C
G
K
R
F
S
Q
S
S
H
L
Y
K
Site 85
S653
C
G
K
R
F
S
Q
S
S
H
L
Y
K
H
S
Site 86
S654
G
K
R
F
S
Q
S
S
H
L
Y
K
H
S
K
Site 87
Y657
F
S
Q
S
S
H
L
Y
K
H
S
K
T
T
C
Site 88
S669
T
T
C
L
R
W
Q
S
S
N
L
P
S
T
L
Site 89
S670
T
C
L
R
W
Q
S
S
N
L
P
S
T
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation