PhosphoNET

           
Protein Info 
   
Short Name:  JMJD3
Full Name:  Lysine-specific demethylase 6B
Alias:  JmjC domain-containing 3; Jumonji domain-containing 3; Jumonji domain-containing protein 3; KIAA0346; Lysine (K)-specific demethylase 6B
Type:  Oxidoreductase; EC 1.14.11.-
Mass (Da):  180411
Number AA:  1679
UniProt ID:  O15054
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0005506  GO:0016702   PhosphoSite+ KinaseNET
Biological Process:  GO:0006954  GO:0055114   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S29LSCAGAWSSCPPHPP
Site 2S30SCAGAWSSCPPHPPP
Site 3S39PPHPPPRSAWLPGGR
Site 4S48WLPGGRCSASIGQPP
Site 5S50PGGRCSASIGQPPLP
Site 6S63LPAPLPPSHGSSSGH
Site 7S66PLPPSHGSSSGHPSK
Site 8S67LPPSHGSSSGHPSKP
Site 9S68PPSHGSSSGHPSKPY
Site 10S72GSSSGHPSKPYYAPG
Site 11Y75SGHPSKPYYAPGAPT
Site 12Y76GHPSKPYYAPGAPTP
Site 13T82YYAPGAPTPRPLHGK
Site 14S92PLHGKLESLHGCVQA
Site 15Y117WEQLGQLYESEHDSE
Site 16S119QLGQLYESEHDSEEA
Site 17S123LYESEHDSEEATRCY
Site 18T127EHDSEEATRCYHSAL
Site 19Y130SEEATRCYHSALRYG
Site 20S132EATRCYHSALRYGGS
Site 21S139SALRYGGSFAELGPR
Site 22Y188HLEHKRNYGAKRGGP
Site 23S215PVPPAALSGPSGEEG
Site 24S218PAALSGPSGEEGLSP
Site 25S224PSGEEGLSPGGKRRR
Site 26S235KRRRGCNSEQTGLPP
Site 27T238RGCNSEQTGLPPGLP
Site 28S268PLPGLATSPPFQLTK
Site 29T274TSPPFQLTKPGLWST
Site 30T281TKPGLWSTLHGDAWG
Site 31S294WGPERKGSAPPERQE
Site 32S305ERQEQRHSLPHPYPY
Site 33Y310RHSLPHPYPYPAPAY
Site 34Y312SLPHPYPYPAPAYTA
Site 35Y317YPYPAPAYTAHPPGH
Site 36T318PYPAPAYTAHPPGHR
Site 37S343PRPPGAESHGCLPAT
Site 38T350SHGCLPATRPPGSDL
Site 39S355PATRPPGSDLRESRV
Site 40S360PGSDLRESRVQRSRM
Site 41S365RESRVQRSRMDSSVS
Site 42S369VQRSRMDSSVSPAAT
Site 43S370QRSRMDSSVSPAATT
Site 44S372SRMDSSVSPAATTAC
Site 45Y382ATTACVPYAPSRPPG
Site 46S385ACVPYAPSRPPGLPG
Site 47T393RPPGLPGTTTSSSSS
Site 48T394PPGLPGTTTSSSSSS
Site 49T395PGLPGTTTSSSSSSS
Site 50S396GLPGTTTSSSSSSSS
Site 51S397LPGTTTSSSSSSSSN
Site 52S398PGTTTSSSSSSSSNT
Site 53S399GTTTSSSSSSSSNTG
Site 54S400TTTSSSSSSSSNTGL
Site 55S401TTSSSSSSSSNTGLR
Site 56S402TSSSSSSSSNTGLRG
Site 57S403SSSSSSSSNTGLRGV
Site 58T405SSSSSSNTGLRGVEP
Site 59Y422GIPGADHYQTPALEV
Site 60T424PGADHYQTPALEVSH
Site 61S438HHGRLGPSAHSSRKP
Site 62S441RLGPSAHSSRKPFLG
Site 63S442LGPSAHSSRKPFLGA
Site 64S457PAATPHLSLPPGPSS
Site 65S463LSLPPGPSSPPPPPC
Site 66S464SLPPGPSSPPPPPCP
Site 67S528GFLGPPASRFSVGTQ
Site 68S531GPPASRFSVGTQDSH
Site 69T534ASRFSVGTQDSHTPP
Site 70S537FSVGTQDSHTPPTPP
Site 71T539VGTQDSHTPPTPPTP
Site 72T542QDSHTPPTPPTPTTS
Site 73T545HTPPTPPTPTTSSSN
Site 74T547PPTPPTPTTSSSNSN
Site 75T548PTPPTPTTSSSNSNS
Site 76S549TPPTPTTSSSNSNSG
Site 77S550PPTPTTSSSNSNSGS
Site 78S551PTPTTSSSNSNSGSH
Site 79S553PTTSSSNSNSGSHSS
Site 80S555TSSSNSNSGSHSSSP
Site 81S557SSNSNSGSHSSSPAG
Site 82S559NSNSGSHSSSPAGPV
Site 83S560SNSGSHSSSPAGPVS
Site 84S561NSGSHSSSPAGPVSF
Site 85S567SSPAGPVSFPPPPYL
Site 86Y573VSFPPPPYLARSIDP
Site 87S577PPPYLARSIDPLPRP
Site 88S586DPLPRPPSPAQNPQD
Site 89S609ALPPAPPSSCHQNTS
Site 90S610LPPAPPSSCHQNTSG
Site 91S616SSCHQNTSGSFRRPE
Site 92S618CHQNTSGSFRRPESP
Site 93S624GSFRRPESPRPRVSF
Site 94S630ESPRPRVSFPKTPEV
Site 95T634PRVSFPKTPEVGPGP
Site 96S647GPPPGPLSKAPQPVP
Site 97T673RLFDFPPTPLEDQFE
Site 98S702IMKMLDESIRKEEEQ
Site 99S728PLKEPFASLQSPFPT
Site 100S731EPFASLQSPFPTDTA
Site 101T735SLQSPFPTDTAPTTT
Site 102T737QSPFPTDTAPTTTAP
Site 103S785LAKFPPPSQPQPPPP
Site 104S796PPPPPPPSPASLLKS
Site 105S799PPPPSPASLLKSLAS
Site 106S806SLLKSLASVLEGQKY
Site 107Y813SVLEGQKYCYRGTGA
Site 108T818QKYCYRGTGAAVSTR
Site 109S823RGTGAAVSTRPGPLP
Site 110T831TRPGPLPTTQYSPGP
Site 111T832RPGPLPTTQYSPGPP
Site 112Y834GPLPTTQYSPGPPSG
Site 113S835PLPTTQYSPGPPSGA
Site 114S840QYSPGPPSGATALPP
Site 115T843PGPPSGATALPPTSA
Site 116S849ATALPPTSAAPSAQG
Site 117S853PPTSAAPSAQGSPQP
Site 118S857AAPSAQGSPQPSASS
Site 119S861AQGSPQPSASSSSQF
Site 120S863GSPQPSASSSSQFST
Site 121S864SPQPSASSSSQFSTS
Site 122S865PQPSASSSSQFSTSG
Site 123S866QPSASSSSQFSTSGG
Site 124S869ASSSSQFSTSGGPWA
Site 125T870SSSSQFSTSGGPWAR
Site 126S871SSSQFSTSGGPWARE
Site 127T891EPVPGPMTPTQPPPP
Site 128T893VPGPMTPTQPPPPLS
Site 129S900TQPPPPLSLPPARSE
Site 130S906LSLPPARSESEVLEE
Site 131S908LPPARSESEVLEEIS
Site 132T930ERVGRSATDPADPVD
Site 133T938DPADPVDTAEPADSG
Site 134S944DTAEPADSGTERLLP
Site 135T946AEPADSGTERLLPPA
Site 136S966AGGVAAVSGSCKRRQ
Site 137S968GVAAVSGSCKRRQKE
Site 138S990HRRACKDSVGRRPRE
Site 139S1011AKVPKEKSRRVLGNL
Site 140S1022LGNLDLQSEEIQGRE
Site 141S1031EIQGREKSRPDLGGA
Site 142S1039RPDLGGASKAKPPTA
Site 143T1045ASKAKPPTAPAPPSA
Site 144S1051PTAPAPPSAPAPSAQ
Site 145S1056PPSAPAPSAQPTPPS
Site 146T1060PAPSAQPTPPSASVP
Site 147S1063SAQPTPPSASVPGKK
Site 148S1065QPTPPSASVPGKKAR
Site 149S1091ADMLKLRSLSEGPPK
Site 150S1093MLKLRSLSEGPPKEL
Site 151S1109IRLIKVESGDKETFI
Site 152T1114VESGDKETFIASEVE
Site 153S1118DKETFIASEVEERRL
Site 154T1131RLRMADLTISHCAAD
Site 155S1143AADVVRASRNAKVKG
Site 156S1155VKGKFRESYLSPAQS
Site 157Y1156KGKFRESYLSPAQSV
Site 158S1158KFRESYLSPAQSVKP
Site 159S1162SYLSPAQSVKPKINT
Site 160T1182REKLNPPTPSIYLES
Site 161Y1186NPPTPSIYLESKRDA
Site 162S1189TPSIYLESKRDAFSP
Site 163S1195ESKRDAFSPVLLQFC
Site 164T1203PVLLQFCTDPRNPIT
Site 165T1210TDPRNPITVIRGLAG
Site 166T1239VEASGEHTVEVRTQV
Site 167S1250RTQVQQPSDENWDLT
Site 168S1270WPCESSRSHTTIAKY
Site 169T1272CESSRSHTTIAKYAQ
Site 170Y1277SHTTIAKYAQYQASS
Site 171Y1280TIAKYAQYQASSFQE
Site 172S1283KYAQYQASSFQESLQ
Site 173S1284YAQYQASSFQESLQE
Site 174S1288QASSFQESLQEEKES
Site 175S1295SLQEEKESEDEESEE
Site 176S1300KESEDEESEEPDSTT
Site 177S1305EESEEPDSTTGTPPS
Site 178T1306ESEEPDSTTGTPPSS
Site 179T1307SEEPDSTTGTPPSSA
Site 180T1309EPDSTTGTPPSSAPD
Site 181S1312STTGTPPSSAPDPKN
Site 182S1313TTGTPPSSAPDPKNH
Site 183S1332FGTNIDLSDAKRWKP
Site 184S1355PAFMRVTSTGNMLSH
Site 185Y1376GMNTVQLYMKVPGSR
Site 186S1382LYMKVPGSRTPGHQE
Site 187T1384MKVPGSRTPGHQENN
Site 188Y1449YASNIPVYRFVQRPG
Site 189T1486AWNVGPLTAYQYQLA
Site 190Y1490GPLTAYQYQLALERY
Site 191Y1497YQLALERYEWNEVKN
Site 192T1521VSWNVARTVKISDPD
Site 193S1525VARTVKISDPDLFKM
Site 194S1550HCQVQRESLVRAGKK
Site 195Y1560RAGKKIAYQGRVKDE
Site 196Y1570RVKDEPAYYCNECDV
Site 197Y1571VKDEPAYYCNECDVE
Site 198S1591FVTSENGSRNTYLVH
Site 199T1594SENGSRNTYLVHCEG
Site 200Y1595ENGSRNTYLVHCEGC
Site 201S1607EGCARRRSAGLQGVV
Site 202T1621VVLEQYRTEELAQAY
Site 203T1632AQAYDAFTLVRARRA
Site 204S1670PEPPPAFSPQAPAST
Site 205S1676FSPQAPASTSR____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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