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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SR140
Full Name:
U2-associated protein SR140
Alias:
KIAA0332; Splicing factor SR family KIAA0332 isoform
Type:
RNA binding protein
Mass (Da):
118292
Number AA:
1029
UniProt ID:
O15042
International Prot ID:
IPI00790699
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
A
D
K
T
P
G
G
S
Q
K
A
Site 2
S9
A
D
K
T
P
G
G
S
Q
K
A
S
S
K
T
Site 3
S13
G
G
S
Q
K
A
S
S
K
T
R
S
S
D
V
Site 4
S14
G
G
S
Q
K
A
S
S
K
T
R
S
S
D
V
Site 5
T16
S
Q
K
A
S
S
K
T
R
S
S
D
V
H
S
Site 6
S18
K
A
S
S
K
T
R
S
S
D
V
H
S
S
G
Site 7
S19
A
S
S
K
T
R
S
S
D
V
H
S
S
G
S
Site 8
S23
T
R
S
S
D
V
H
S
S
G
S
S
D
A
H
Site 9
S24
R
S
S
D
V
H
S
S
G
S
S
D
A
H
M
Site 10
S27
D
V
H
S
S
G
S
S
D
A
H
M
D
A
S
Site 11
S34
S
D
A
H
M
D
A
S
G
P
S
D
S
D
M
Site 12
S37
H
M
D
A
S
G
P
S
D
S
D
M
P
S
R
Site 13
S39
D
A
S
G
P
S
D
S
D
M
P
S
R
T
R
Site 14
S43
P
S
D
S
D
M
P
S
R
T
R
P
K
S
P
Site 15
T45
D
S
D
M
P
S
R
T
R
P
K
S
P
R
K
Site 16
S49
P
S
R
T
R
P
K
S
P
R
K
H
N
Y
R
Site 17
Y55
K
S
P
R
K
H
N
Y
R
N
E
S
A
R
E
Site 18
S59
K
H
N
Y
R
N
E
S
A
R
E
S
L
C
D
Site 19
S63
R
N
E
S
A
R
E
S
L
C
D
S
P
H
Q
Site 20
S67
A
R
E
S
L
C
D
S
P
H
Q
N
L
S
R
Site 21
S73
D
S
P
H
Q
N
L
S
R
P
L
L
E
N
K
Site 22
T91
F
S
I
G
K
M
S
T
A
K
R
T
L
S
K
Site 23
T95
K
M
S
T
A
K
R
T
L
S
K
K
E
Q
E
Site 24
S97
S
T
A
K
R
T
L
S
K
K
E
Q
E
E
L
Site 25
Y117
E
K
A
A
A
E
I
Y
E
E
F
L
A
A
F
Site 26
T134
S
D
G
N
K
V
K
T
F
V
R
G
G
V
V
Site 27
T150
A
A
K
E
E
H
E
T
D
E
K
R
G
K
I
Site 28
Y158
D
E
K
R
G
K
I
Y
K
P
S
S
R
F
A
Site 29
S161
R
G
K
I
Y
K
P
S
S
R
F
A
D
Q
K
Site 30
S162
G
K
I
Y
K
P
S
S
R
F
A
D
Q
K
N
Site 31
S175
K
N
P
P
N
Q
S
S
N
E
R
P
P
S
L
Site 32
S181
S
S
N
E
R
P
P
S
L
L
V
I
E
T
K
Site 33
T187
P
S
L
L
V
I
E
T
K
K
P
P
L
K
K
Site 34
S202
G
E
K
E
K
K
K
S
N
L
E
L
F
K
E
Site 35
T224
E
R
D
E
R
H
K
T
K
G
R
L
S
R
F
Site 36
S229
H
K
T
K
G
R
L
S
R
F
E
P
P
Q
S
Site 37
S236
S
R
F
E
P
P
Q
S
D
S
D
G
Q
R
R
Site 38
S238
F
E
P
P
Q
S
D
S
D
G
Q
R
R
S
M
Site 39
S244
D
S
D
G
Q
R
R
S
M
D
A
P
S
R
R
Site 40
S249
R
R
S
M
D
A
P
S
R
R
N
R
S
S
G
Site 41
S254
A
P
S
R
R
N
R
S
S
G
V
L
D
D
Y
Site 42
S255
P
S
R
R
N
R
S
S
G
V
L
D
D
Y
A
Site 43
Y261
S
S
G
V
L
D
D
Y
A
P
G
S
H
D
V
Site 44
S265
L
D
D
Y
A
P
G
S
H
D
V
G
D
P
S
Site 45
S272
S
H
D
V
G
D
P
S
T
T
N
L
Y
L
G
Site 46
T273
H
D
V
G
D
P
S
T
T
N
L
Y
L
G
N
Site 47
Y277
D
P
S
T
T
N
L
Y
L
G
N
I
N
P
Q
Site 48
S302
G
R
F
G
P
L
A
S
V
K
I
M
W
P
R
Site 49
Y364
P
I
P
P
H
P
I
Y
I
P
P
S
M
M
E
Site 50
T373
P
P
S
M
M
E
H
T
L
P
P
P
P
S
G
Site 51
S379
H
T
L
P
P
P
P
S
G
L
P
F
N
A
Q
Site 52
T411
N
K
E
D
F
E
K
T
L
S
Q
A
I
V
K
Site 53
T467
R
F
L
F
E
N
Q
T
P
A
H
V
Y
Y
R
Site 54
Y472
N
Q
T
P
A
H
V
Y
Y
R
W
K
L
Y
S
Site 55
Y478
V
Y
Y
R
W
K
L
Y
S
I
L
Q
G
D
S
Site 56
S479
Y
Y
R
W
K
L
Y
S
I
L
Q
G
D
S
P
Site 57
S485
Y
S
I
L
Q
G
D
S
P
T
K
W
R
T
E
Site 58
T487
I
L
Q
G
D
S
P
T
K
W
R
T
E
D
F
Site 59
S501
F
R
M
F
K
N
G
S
F
W
R
P
P
P
L
Site 60
Y511
R
P
P
P
L
N
P
Y
L
H
G
M
S
E
E
Site 61
S516
N
P
Y
L
H
G
M
S
E
E
Q
E
T
E
A
Site 62
T521
G
M
S
E
E
Q
E
T
E
A
F
V
E
E
P
Site 63
T550
E
E
I
L
R
G
L
T
P
R
K
N
D
I
G
Site 64
T586
E
S
L
S
I
L
K
T
P
L
P
K
K
I
A
Site 65
S613
S
A
K
V
A
N
A
S
Y
Y
R
K
F
F
E
Site 66
Y614
A
K
V
A
N
A
S
Y
Y
R
K
F
F
E
T
Site 67
Y615
K
V
A
N
A
S
Y
Y
R
K
F
F
E
T
K
Site 68
S628
T
K
L
C
Q
I
F
S
D
L
N
A
T
Y
R
Site 69
Y634
F
S
D
L
N
A
T
Y
R
T
I
Q
G
H
L
Site 70
S643
T
I
Q
G
H
L
Q
S
E
N
F
K
Q
R
V
Site 71
Y663
A
W
E
D
W
A
I
Y
P
E
P
F
L
I
K
Site 72
T687
N
I
I
E
E
K
E
T
E
D
V
P
D
D
L
Site 73
T719
D
G
I
P
I
D
A
T
P
I
D
D
L
D
G
Site 74
S731
L
D
G
V
P
I
K
S
L
D
D
D
L
D
G
Site 75
T744
D
G
V
P
L
D
A
T
E
D
S
K
K
N
E
Site 76
S747
P
L
D
A
T
E
D
S
K
K
N
E
P
I
F
Site 77
S759
P
I
F
K
V
A
P
S
K
W
E
A
V
D
E
Site 78
S788
L
F
D
Q
H
E
E
S
E
E
E
E
N
Q
N
Site 79
S800
N
Q
N
Q
E
E
E
S
E
D
E
E
D
T
Q
Site 80
T806
E
S
E
D
E
E
D
T
Q
S
S
K
S
E
E
Site 81
S808
E
D
E
E
D
T
Q
S
S
K
S
E
E
H
H
Site 82
S809
D
E
E
D
T
Q
S
S
K
S
E
E
H
H
L
Site 83
S811
E
D
T
Q
S
S
K
S
E
E
H
H
L
Y
S
Site 84
Y817
K
S
E
E
H
H
L
Y
S
N
P
I
K
E
E
Site 85
S818
S
E
E
H
H
L
Y
S
N
P
I
K
E
E
M
Site 86
T826
N
P
I
K
E
E
M
T
E
S
K
F
S
K
Y
Site 87
S828
I
K
E
E
M
T
E
S
K
F
S
K
Y
S
E
Site 88
S831
E
M
T
E
S
K
F
S
K
Y
S
E
M
S
E
Site 89
Y833
T
E
S
K
F
S
K
Y
S
E
M
S
E
E
K
Site 90
S834
E
S
K
F
S
K
Y
S
E
M
S
E
E
K
R
Site 91
S870
R
P
K
K
P
G
Q
S
F
Q
E
Q
V
E
H
Site 92
T919
K
K
E
K
D
E
C
T
P
T
R
K
E
R
K
Site 93
T921
E
K
D
E
C
T
P
T
R
K
E
R
K
R
R
Site 94
S930
K
E
R
K
R
R
H
S
T
S
P
S
P
S
R
Site 95
T931
E
R
K
R
R
H
S
T
S
P
S
P
S
R
S
Site 96
S932
R
K
R
R
H
S
T
S
P
S
P
S
R
S
S
Site 97
S934
R
R
H
S
T
S
P
S
P
S
R
S
S
S
G
Site 98
S936
H
S
T
S
P
S
P
S
R
S
S
S
G
R
R
Site 99
S938
T
S
P
S
P
S
R
S
S
S
G
R
R
V
K
Site 100
S939
S
P
S
P
S
R
S
S
S
G
R
R
V
K
S
Site 101
S940
P
S
P
S
R
S
S
S
G
R
R
V
K
S
P
Site 102
S946
S
S
G
R
R
V
K
S
P
S
P
K
S
E
R
Site 103
S948
G
R
R
V
K
S
P
S
P
K
S
E
R
S
E
Site 104
S951
V
K
S
P
S
P
K
S
E
R
S
E
R
S
E
Site 105
S954
P
S
P
K
S
E
R
S
E
R
S
E
R
S
H
Site 106
S957
K
S
E
R
S
E
R
S
E
R
S
H
K
E
S
Site 107
S960
R
S
E
R
S
E
R
S
H
K
E
S
S
R
S
Site 108
S964
S
E
R
S
H
K
E
S
S
R
S
R
S
S
H
Site 109
S965
E
R
S
H
K
E
S
S
R
S
R
S
S
H
K
Site 110
S967
S
H
K
E
S
S
R
S
R
S
S
H
K
D
S
Site 111
S969
K
E
S
S
R
S
R
S
S
H
K
D
S
P
R
Site 112
S970
E
S
S
R
S
R
S
S
H
K
D
S
P
R
D
Site 113
S974
S
R
S
S
H
K
D
S
P
R
D
V
S
K
K
Site 114
S979
K
D
S
P
R
D
V
S
K
K
A
K
R
S
P
Site 115
S985
V
S
K
K
A
K
R
S
P
S
G
S
R
T
P
Site 116
S987
K
K
A
K
R
S
P
S
G
S
R
T
P
K
R
Site 117
S989
A
K
R
S
P
S
G
S
R
T
P
K
R
S
R
Site 118
T991
R
S
P
S
G
S
R
T
P
K
R
S
R
R
S
Site 119
S995
G
S
R
T
P
K
R
S
R
R
S
R
S
R
S
Site 120
S998
T
P
K
R
S
R
R
S
R
S
R
S
P
K
K
Site 121
S1000
K
R
S
R
R
S
R
S
R
S
P
K
K
S
G
Site 122
S1002
S
R
R
S
R
S
R
S
P
K
K
S
G
K
K
Site 123
S1006
R
S
R
S
P
K
K
S
G
K
K
S
R
S
Q
Site 124
S1010
P
K
K
S
G
K
K
S
R
S
Q
S
R
S
P
Site 125
S1012
K
S
G
K
K
S
R
S
Q
S
R
S
P
H
R
Site 126
S1014
G
K
K
S
R
S
Q
S
R
S
P
H
R
S
H
Site 127
S1016
K
S
R
S
Q
S
R
S
P
H
R
S
H
K
K
Site 128
S1020
Q
S
R
S
P
H
R
S
H
K
K
S
K
K
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation