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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0317
Full Name:
Protein KIAA0317
Alias:
Type:
Mass (Da):
94223
Number AA:
823
UniProt ID:
O15033
International Prot ID:
IPI00006561
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0016881
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0006464
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
E
L
A
A
R
V
V
S
F
L
Q
N
E
D
R
Site 2
T45
R
E
R
R
G
D
R
T
I
Y
D
Y
V
R
G
Site 3
Y47
R
R
G
D
R
T
I
Y
D
Y
V
R
G
N
Y
Site 4
Y49
G
D
R
T
I
Y
D
Y
V
R
G
N
Y
L
D
Site 5
Y54
Y
D
Y
V
R
G
N
Y
L
D
P
R
S
C
K
Site 6
Y70
S
W
D
W
K
D
P
Y
E
V
G
H
S
M
A
Site 7
Y84
A
F
R
V
H
L
F
Y
K
N
G
Q
P
F
P
Site 8
T131
N
V
V
K
V
A
F
T
V
R
K
A
G
R
Y
Site 9
Y138
T
V
R
K
A
G
R
Y
E
I
T
V
K
L
G
Site 10
T141
K
A
G
R
Y
E
I
T
V
K
L
G
G
L
N
Site 11
S152
G
G
L
N
V
A
Y
S
P
Y
Y
K
I
F
Q
Site 12
Y154
L
N
V
A
Y
S
P
Y
Y
K
I
F
Q
P
G
Site 13
Y155
N
V
A
Y
S
P
Y
Y
K
I
F
Q
P
G
M
Site 14
T186
L
T
C
G
Q
P
H
T
L
Q
I
V
P
R
D
Site 15
Y195
Q
I
V
P
R
D
E
Y
D
N
P
T
N
N
S
Site 16
T199
R
D
E
Y
D
N
P
T
N
N
S
M
S
L
R
Site 17
S204
N
P
T
N
N
S
M
S
L
R
D
E
H
N
Y
Site 18
Y211
S
L
R
D
E
H
N
Y
T
L
S
I
H
E
L
Site 19
T212
L
R
D
E
H
N
Y
T
L
S
I
H
E
L
G
Site 20
T226
G
P
Q
E
E
E
S
T
G
V
S
F
E
K
S
Site 21
S229
E
E
E
S
T
G
V
S
F
E
K
S
V
T
S
Site 22
S233
T
G
V
S
F
E
K
S
V
T
S
N
R
Q
T
Site 23
T235
V
S
F
E
K
S
V
T
S
N
R
Q
T
F
Q
Site 24
S236
S
F
E
K
S
V
T
S
N
R
Q
T
F
Q
V
Site 25
T240
S
V
T
S
N
R
Q
T
F
Q
V
F
L
R
L
Site 26
S289
N
I
V
E
R
N
V
S
T
S
G
V
S
I
Y
Site 27
S291
V
E
R
N
V
S
T
S
G
V
S
I
Y
F
E
Site 28
Y296
S
T
S
G
V
S
I
Y
F
E
A
Y
L
Y
N
Site 29
Y302
I
Y
F
E
A
Y
L
Y
N
A
T
N
C
S
S
Site 30
T310
N
A
T
N
C
S
S
T
P
W
H
L
P
P
M
Site 31
S321
L
P
P
M
H
M
T
S
S
Q
R
R
P
S
T
Site 32
S322
P
P
M
H
M
T
S
S
Q
R
R
P
S
T
A
Site 33
S327
T
S
S
Q
R
R
P
S
T
A
V
D
E
E
D
Site 34
T328
S
S
Q
R
R
P
S
T
A
V
D
E
E
D
E
Site 35
S337
V
D
E
E
D
E
D
S
P
S
E
C
H
T
P
Site 36
S339
E
E
D
E
D
S
P
S
E
C
H
T
P
E
K
Site 37
T343
D
S
P
S
E
C
H
T
P
E
K
V
K
K
P
Site 38
Y354
V
K
K
P
K
K
V
Y
C
Y
V
S
P
K
Q
Site 39
Y356
K
P
K
K
V
Y
C
Y
V
S
P
K
Q
F
S
Site 40
S358
K
K
V
Y
C
Y
V
S
P
K
Q
F
S
V
K
Site 41
Y368
Q
F
S
V
K
E
F
Y
L
K
I
I
P
W
R
Site 42
T385
T
F
R
V
C
P
G
T
K
F
S
Y
L
G
P
Site 43
Y389
C
P
G
T
K
F
S
Y
L
G
P
D
P
V
H
Site 44
T424
E
R
N
I
L
A
A
T
F
I
R
S
L
H
K
Site 45
T438
K
N
I
G
G
S
E
T
F
Q
D
K
V
N
F
Site 46
S460
V
H
M
K
R
P
H
S
K
V
T
L
K
V
S
Site 47
T463
K
R
P
H
S
K
V
T
L
K
V
S
R
H
A
Site 48
S467
S
K
V
T
L
K
V
S
R
H
A
L
L
E
S
Site 49
S475
R
H
A
L
L
E
S
S
L
K
A
T
R
N
F
Site 50
T479
L
E
S
S
L
K
A
T
R
N
F
S
I
S
D
Site 51
S483
L
K
A
T
R
N
F
S
I
S
D
W
S
K
N
Site 52
S485
A
T
R
N
F
S
I
S
D
W
S
K
N
F
E
Site 53
S530
N
Q
L
F
T
R
F
S
D
N
N
Q
A
L
V
Site 54
Y564
R
L
V
G
K
C
L
Y
E
S
S
L
G
G
A
Site 55
S566
V
G
K
C
L
Y
E
S
S
L
G
G
A
Y
K
Site 56
S567
G
K
C
L
Y
E
S
S
L
G
G
A
Y
K
Q
Site 57
Y572
E
S
S
L
G
G
A
Y
K
Q
L
V
R
A
R
Site 58
Y595
I
I
G
L
R
M
H
Y
K
Y
F
E
T
D
D
Site 59
Y597
G
L
R
M
H
Y
K
Y
F
E
T
D
D
P
E
Site 60
Y606
E
T
D
D
P
E
F
Y
K
S
K
V
C
F
I
Site 61
Y630
L
V
F
A
E
E
K
Y
N
K
S
G
Q
L
D
Site 62
S633
A
E
E
K
Y
N
K
S
G
Q
L
D
K
V
V
Site 63
T649
L
M
T
G
G
A
Q
T
P
V
T
N
A
N
K
Site 64
T652
G
G
A
Q
T
P
V
T
N
A
N
K
I
F
Y
Site 65
S670
L
A
Q
Y
R
L
A
S
Q
V
K
E
E
V
E
Site 66
S711
M
C
G
T
G
D
I
S
V
S
D
F
K
A
H
Site 67
S713
G
T
G
D
I
S
V
S
D
F
K
A
H
A
V
Site 68
T756
A
R
L
L
Q
F
T
T
G
S
S
Q
L
P
P
Site 69
S758
L
L
Q
F
T
T
G
S
S
Q
L
P
P
G
G
Site 70
S759
L
Q
F
T
T
G
S
S
Q
L
P
P
G
G
F
Site 71
T786
P
T
H
S
T
L
P
T
A
H
T
C
F
N
Q
Site 72
Y799
N
Q
L
C
L
P
T
Y
D
S
Y
E
E
V
H
Site 73
S801
L
C
L
P
T
Y
D
S
Y
E
E
V
H
R
M
Site 74
Y802
C
L
P
T
Y
D
S
Y
E
E
V
H
R
M
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation